dnaK / Hsp70 antibody

Principal name

dnaK / Hsp70 antibody

Alternative names for dnaK / Hsp70 antibody

Heat shock protein 70, Heat shock 70 kDa protein, Rv0350, MT0365, MTCY13E10.10, Chaperone protein dnaK

SwissProt ID

P0A5B9 (Myctu), P0A6Y8 (Ecoli)

Gene ID

944750 (dnaK), 885946

Available reactivities

Mycobacteria

Available hosts

Mouse

Available applications

Enzyme Immunoassay (E), ELISA (capture) (E(capture)), Western blot / Immunoblot (WB), ELISA (detection) (E(detection))

Background of dnaK / Hsp70 antibody

Heat shock proteins (HSPs) or stress response proteins (SRPs) are synthesized in variety of environmental and pathophysiological stressful conditions. Many HSPs are involved in processes such as protein denaturation-renaturation, folding-unfolding, transport-translocation, activation-inactivation, and secretion. HSP70 is found to be associated with steroid receptors, actin, p53, polyoma T antigen, nucleotides, and other unknown proteins. Also, HSP70 has been shown to be involved in protective roles against thermal stress, cytotoxic drugs, and other damaging conditions.

Heat shock proteins are produced by prokaryotic and eukaryotic cells, and are among the most conserved molecules in phylogeny. Eukaryotic cells contain an HSP70 multigene that differ in their intracellular location and regulation. Members of the HSP70 family play a major role in the folding, unfolding and translocation of polypeptides as well as in the assembly and disassembly of oligomeric protein complexes, as well as in the immune response. HSP72 was found to increase dramatically in the brains of Alzheimer’s disease patients, and was localized exclusively in neuritic plaques and neurofibrillary tangles. HSP70 concentrates in nuclei during heat shock and returns to the cytoplasm when the shock is removed.

General readings

Bardwell & Craig (1984) Proc. Natl. Acad. Sci. 81, 848-852.
Zhu et al., (1996) Science 272, 1606-1614.

20 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

dnaK / Hsp70 (161-370) antibody

dnaK / Hsp70 Mouse IgG1 TS29 Purified Mycobacteria E, E(capture), WB
1 mg / €630.00
  HyTest Ltd.

dnaK / Hsp70 (N-term) antibody

dnaK / Hsp70 Mouse IgG2a TS31 Purified Mycobacteria E, E(capture), WB
1 mg / €630.00
  HyTest Ltd.

dnaK / Hsp70 (C-term) antibody

dnaK / Hsp70 Mouse IgG2b TS489 Purified Mycobacteria E, E(detection), WB
1 mg / €630.00
  HyTest Ltd.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

dnaK / Hsp70

dnaK / Hsp70 Bacterial ~95% by SDS-PAGE
0.1 mg / €570.00
  Acris Antibodies GmbH

dnaK / Hsp70 (Substrate binding domain)

dnaK / Hsp70 E. coli Purified > 95 % by SDS-PAGE E. coli
0.1 mg / €230.00
  Acris Antibodies GmbH

dnaK / Hsp70 (Substrate binding domain)

dnaK / Hsp70 E. coli Purified > 95 % by SDS-PAGE E. coli
0.5 mg / €540.00
  Acris Antibodies GmbH

dnaK / Hsp70 (full length)

dnaK / Hsp70 E. coli Purified > 95 % by SDS-PAGE E. coli
0.1 mg / €230.00
  Acris Antibodies GmbH

dnaK / Hsp70 (full length)

dnaK / Hsp70 E. coli Purified > 95 % by SDS-PAGE E. coli
0.5 mg / €540.00
  Acris Antibodies GmbH

dnaK / Hsp70 (1-384)

dnaK / Hsp70 E. coli Purified > 95 % by SDS-PAGE E. coli
0.1 mg / €230.00
  Acris Antibodies GmbH

dnaK / Hsp70 (1-384)

dnaK / Hsp70 E. coli Purified > 95 % by SDS-PAGE E. coli
0.5 mg / €540.00
  Acris Antibodies GmbH

dnaK / Hsp70 (385-638)

dnaK / Hsp70 E. coli Purified > 95 % by SDS-PAGE E. coli
0.1 mg / €230.00
  Acris Antibodies GmbH

dnaK / Hsp70 (385-638)

dnaK / Hsp70 E. coli Purified > 95 % by SDS-PAGE E. coli
0.5 mg / €540.00
  Acris Antibodies GmbH

dnaK / Hsp70 (508-638)

Recombinant Dna K (amino acids 508-638): 14% SDS-PAGE E. coli Purified > 95 % by SDS-PAGE E. coli
0.1 mg / €230.00
  Acris Antibodies GmbH

dnaK / Hsp70 (508-638)

Recombinant Dna K (amino acids 508-638): 14% SDS-PAGE E. coli Purified > 95 % by SDS-PAGE E. coli
0.5 mg / €540.00
  Acris Antibodies GmbH

dnaK / Hsp70

dnaK / Hsp70
0.1 mg / €330.00
  Abnova Taiwan Corp.

dnaK / Hsp70

dnaK / Hsp70
0.1 mg / €330.00
  Abnova Taiwan Corp.

dnaK / Hsp70

dnaK / Hsp70
0.1 mg / €330.00
  Abnova Taiwan Corp.

dnaK / Hsp70

dnaK / Hsp70
0.1 mg / €330.00
  Abnova Taiwan Corp.

dnaK / Hsp70

dnaK / Hsp70
0.1 mg / €330.00
  Abnova Taiwan Corp.

dnaK / Hsp70

dnaK / Hsp70 Mycobacteria Purified > 95 % E. coli
0.1 mg / €1,680.00
  HyTest Ltd.

20 Item(s)

per page
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