DNMT3B antibody
Principal name
DNMT3B antibody
Alternative names for DNMT3B antibody
DNA MTase HsaIIIB, M.HsaIIIB, DNA (cytosine-5)-methyltransferase 3B, DNA methyltransferase HsaIIIB
Ncbi ID
9606, 10090, NP_008823.1, NP_008823, NP_787045, AAI18503.1, NM_175849, NM_006892, NP_001193984.1, NP_001003960.2, NM_001003961, NM_001003960, NM_010068, NM_001003963, NM_001122997, NM_175850
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ChIP assay (ChIP), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Frozen Sections (C), Flow Cytometry (F)
Background of DNMT3B antibody
DNMT3B is required for genome wide de novo methylation and is essential for the establishment of D methylation patterns during development. D methylation is coordited with methylation of histones. DNMT3B may preferentially methylate nucleosomal D within the nucleosome core region. DNMT3B may function as transcriptiol co-repressor by associating with CBX4 and independently of D methylation. DNMT3B seems to be involved in gene silencing. In association with DNMT1 and via the recruitment of CTCFL/BORIS, DNMT3B is involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome ictivation. Studies in mice have demonstrated that D methylation is required for mammalian development. This gene encodes a D methyltransferase which is thought to function in de novo methylation, rather than maintence methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Six altertively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.



































- Quick-Filters:
- Highly Validated (1)
Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
---|---|---|---|---|---|---|---|
TA313761 | DNMT3B antibody |
||||||
Rabbit polyclonal anti-DNMT3B antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu | E, ICC/IF, P, WB |
0.1 ml /
€335.00
|
|
OriGene Technologies, Inc. | |||||||
![]() |
Highly validated antibody! |
||||||
TA327439 | DNMT3B antibody |
||||||
DNMT3B Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 mg /
€335.00
|
|
OriGene Technologies, Inc. | |||||||
TA331002 | DNMT3B antibody |
||||||
Rabbit polyclonal Anti-DNMT3B Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze | WB |
50 µg /
€360.00
|
|
OriGene Technologies, Inc. | |||||||
![]() |
|||||||
TA336294 | DNMT3B antibody |
||||||
Rabbit Polyclonal DNMT3B Antibody | |||||||
![]() |
Rabbit | Purified | Hu, Ms | C, ICC/IF, IP, P, WB |
0.1 ml /
€416.00
|
||
OriGene Technologies, Inc. | |||||||
![]() |
|||||||
TA347116 | DNMT3B antibody |
||||||
Rabbit Polyclonal DNMT3B Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu | E |
50 µg /
€392.00
|
|
OriGene Technologies, Inc. | |||||||
![]() |
|||||||
TA347117 | DNMT3B antibody |
||||||
Rabbit Polyclonal DNMT3B Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms | E |
0.1 ml /
€335.00
|
|
OriGene Technologies, Inc. | |||||||
![]() |
|||||||
AP01182PU-N | DNMT3B antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu | P, WB |
0.1 mg /
€350.00
|
||
Acris Antibodies GmbH | |||||||
![]() |
|||||||
AP11052PU-N | DNMT3B antibody |
||||||
![]() |
Rabbit | Ig | Purified | Hu | P, WB |
0.4 ml /
€370.00
|
|
Acris Antibodies GmbH | |||||||
![]() |
|||||||
AP31351PU-N | DNMT3B (1-50) antibody |
||||||
![]() |
Rabbit | IgG | Purified | Hu | E, ICC/IF, P, WB |
50 µl /
€380.00
|
|
Acris Antibodies GmbH | |||||||
![]() |
|||||||
C11809-1 | DNMT3B antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu | E, ICC/IF, P, WB |
50 µg /
€230.00
|
||
Assay Biotech | |||||||
![]() |
|||||||
C11809-2 | DNMT3B antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu | E, ICC/IF, P, WB |
0.1 mg /
€330.00
|
||
Assay Biotech | |||||||
![]() |
CRISPR
Catalog No. | Species | Donor Vector | |
---|---|---|---|
KN221966 | DNMT3B - human gene knockout kit via CRISPR |
||
![]() |
Human | GFP-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN221966BN | DNMT3B - human gene knockout kit via CRISPR |
||
![]() |
Human | mBFP-Neo |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN221966LP | DNMT3B - human gene knockout kit via CRISPR |
||
![]() |
Human | Luciferase-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN221966RB | DNMT3B - human gene knockout kit via CRISPR |
||
![]() |
Human | RFP-BSD |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN304724 | Dnmt3b - mouse gene knockout kit via CRISPR |
||
![]() |
Mouse | GFP-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN304724BN | Dnmt3b - mouse gene knockout kit via CRISPR |
||
![]() |
Mouse | mBFP-Neo |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN304724LP | Dnmt3b - mouse gene knockout kit via CRISPR |
||
![]() |
Mouse | Luciferase-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN304724RB | Dnmt3b - mouse gene knockout kit via CRISPR |
||
![]() |
Mouse | RFP-BSD |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. |
Proteins & Growth Factors
Catalog No. | Species | Pres. | Purity | Source | |
---|---|---|---|---|---|
TP323206 | DNMT3B (transcript variant 1) |
||||
Recombinant protein of human DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B), transcript variant 1 | |||||
![]() |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€680.00
|
|
OriGene Technologies, Inc. |