DOC2B antibody

Principal name

DOC2B antibody

Alternative names for DOC2B antibody

Doc2-beta, DOC2BL, Double C2-like domain-containing protein beta

SwissProt ID

P70169 (Mouse), P70610 (Rat), Q14184 (Human)

Gene ID

8447 (DOC2B), 81820 (Doc2b)

Available reactivities

Ms (Mouse), Rt (Rat), Hu (Human)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of DOC2B antibody

Doc2b (double C2 domain) serves as an effector of insulin secretion and skeletal muscle insulin sensitivity. It plays a role in insulin-dependent GLUT4 transport to the plasma membrane in adipocytes and in glucose-stimulated insulin secretion in pancreatic cells. Doc2b is involved in the exocytosis of intracellular vesicles, such as insulin granules, by regulating the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) and Sec1/Munc18 (SM) proteins. As a Ca(2+) sensor, Doc2b also regulates asynchronous neurotransmitter release in the absence of action potentials in neuronal cells.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DOC2B antibody

Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and COS cells transiently transfected with GFP-tagged Doc2b or untagged Kv2.1 plasmids and probed with N150/21 (left), N86/8 (middle) and K89/41 (right). Mouse IgG1 N150/21 Supernatant Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

DOC2B antibody

Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and COS cells transiently transfected with GFP-tagged Doc2b or untagged Kv2.1 plasmids and probed with N150/21 (left), N86/8 (middle) and K89/41 (right). Mouse IgG1 N150/21 Purified Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

DOC2B antibody

DOC2B MaxPab polyclonal antibody. Western Blot analysis of DOC2B expression in human kidney. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

DOC2B antibody

DOC2B Rabbit IgG Purified Ms, Rt P
0.5 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DOC2B

DOC2B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

DOC2B

DOC2B Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

DOC2B

DOC2B Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

DOC2B 293T Cell Transient Overexpression Lysate(Denatured)

DOC2B 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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