DOCK1 / DOCK180 antibody

Principal name

DOCK1 / DOCK180 antibody

Alternative names for DOCK1 / DOCK180 antibody

Dedicator of cytokinesis protein 1, 180 kDa protein downstream of CRK

SwissProt ID

Q14185 (Human), Q8BUR4 (Mouse)

Gene ID

1793 (DOCK1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Por (Porcine), Rt (Rat)

Available hosts

Goat, Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Dot blot (Dot)

Background of DOCK1 / DOCK180 antibody

The v-Crk oncogene product shares homologous amino acid sequences, designated Src homology region 2 (SH2) and SH3, with many molecules involved in signal transduction. The v-Crk cellular homolog, c-Crk, is a member of a newly emerging class of genes including Nck and GRB2/ASH which encode proteins that consist primarily of SH2 and SH3 domains. Two distinct human c-Crk cDNAs, designated Crk I and Crk II, have been identified and shown to represent alternative splice products of c-Crk. The major translational product of c-Crk I has been identified as a 28 kDa variably expressed protein, while c-Crk II encodes a widely expressed 40 kDa protein and a more variably expressed 42 kDa protein.
The major c-Crk transforming activity appears associated with c-Crk I p28 expression. DOCK 180, a 180 kDa protein downstream of Crk, has been identified as a major Crk-associated protein. When DOCK 180 is recruited to the plasma membrane from a cytoplasmic reservoir, presumably by Crk, changes in cellular morphology and spindle formation occur, suggesting DOCK 180 to be a Crk effector molecule.

General readings

Hasegawa H, Kiyokawa E, Tanaka S, Nagashima K, Gotoh N, Shibuya M, Kurata T, Matsuda M.
DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane.
Mol Cell Biol 1996 Apr;16(4):1770-6
PMID: 8657152

16 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DOCK1 / DOCK180 (C-term) antibody

TA302729 staining (4µg/ml) of A431 lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 12 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DOCK1 / DOCK180 antibody

Sample(30 ug of whole cell lysate). A:293T. 7.5% SDS PAGE. TA308798 diluted at 1:1000 Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DOCK1 / DOCK180 antibody

Western blot analysis of extracts from HeLa cells, using DOCK1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DOCK1 / DOCK180 antibody

Western blot (WB) analysis of DOCK 180 antibody (Cat.-No.: AP21159PU-N) in extracts from HUVEC cells. Rabbit Aff - Purified Hu, Ms WB
0.1 mg / €350.00
  Acris Antibodies GmbH

DOCK1 / DOCK180 antibody

DOCK1 / DOCK180 Mouse IgG2b 3D10 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

DOCK1 / DOCK180 antibody

DOCK1 polyclonal antibody ( Cat # PAB6058 ) staining ( 4 µg/ml ) of A-431 lysate ( RIPA buffer, 35 µg total protein per lane ) . Primary incubated for 12 hour. Detected by western blot using chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

DOCK1 / DOCK180 antibody

Western blot analysis of extracts from HeLa cells, using DOCK1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €205.00
  Assay Biotech

DOCK1 / DOCK180 antibody

Western blot analysis of extracts from HeLa cells, using DOCK1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €310.00
  Assay Biotech

DOCK1 / DOCK180 antibody

NB 100-828 staining (4µg/ml) of A431 lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence. Goat IgG Aff - Purified Hu WB
0.1 mg / €400.00
  Novus Biologicals Inc.

DOCK1 / DOCK180 antibody

Immunohistochemistry: DOCK1 Antibody [NBP1-30945] - Immunohistochemical analysis of paraffin-embedded Lung CA, using DOCK 1 antibody at 1:100 dilution. Rabbit IgG Hu Dot, ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

DOCK1 / DOCK180 antibody

DOCK1 / DOCK180 Rabbit IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

DOCK1 / DOCK180 antibody

DOCK1 / DOCK180 Rabbit IgG Aff - Purified Hu, Ms E, WB
50 µg / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DOCK1 / DOCK180

DOCK1 / DOCK180 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

DOCK1 / DOCK180

DOCK1 / DOCK180 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

DOCK1 / DOCK180

DOCK1 / DOCK180 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

DOCK1 / DOCK180

DOCK1 / DOCK180 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

16 Item(s)

per page
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