DOK3 antibody

Principal name

DOK3 antibody

Alternative names for DOK3 antibody

Docking protein 3, Downstream of tyrosine kinase 3

SwissProt ID

A3R064 (Chick), B2RYG7 (Rat), Q7L591 (Human), Q9QZK7 (Mouse)

Gene ID

79930 (DOK3)

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat), Hst (Hamster), Mky (Monkey), Rb (Rabbit)

Available hosts

Goat, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of DOK3 antibody

DOK3 gene maps to chromosome 5q35.3. Dok3 was tyrosine phosphorylated by Src family members Lck; Fyn; and Lyn. Immunoprecipitation studies showed that Dok3 bound inhibitors SHIP and Csk but did not bind RasGAP. Dok3 binding to SHIP occurred via the SH2 domain. Dok3 also bound Csk via the Csk SH2 domain with possible involvement of the Csk SH3 domain as well.DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular sigling complexes. DOK3 is a negative regulator of JNK sigling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function

General readings

Berger, A.H., et al. Nat. Genet. 42(3):216-223 (2010).
Senis, Y.A., et al. J. Thromb. Haemost. 7(10):1718-1726 (2009).
Honma, M., et al. Genes Cells 11(2):143-151 (2006).
Robson, J.D., et al. Mol. Cell. Biol. 24(6):2332-2343 (2004).
Favre, C., et al. Genes Immun. 4(1):40-45 (2003).

20 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DOK3 (C-term) antibody

TA302734 staining (1µg/ml) of Human PBMC lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DOK3 antibody

Sample (30 ug of whole cell lysate). A: A431 . 10% SDS PAGE. TA308614 diluted at 1:1000. Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DOK3 (C-term) antibody

Anti-DOK3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 6.125 ug/ml. Goat IgG Aff - Purified Bov, Hu, Ms, Rt E, P, WB
50 µg / €345.00
  OriGene Technologies, Inc.

DOK3 antibody

Predicted band size: 53 kDa . Positive control: Human notum skin cancer tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DOK3 antibody

Predicted band size: 53 kDa . Positive control: Human notum skin cancer tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/250 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DOK3 antibody

Western blot analysis of extracts from HepG2 cells, using DOK3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DOK3 antibody

Western blot analysis on HepG2 cell lysate using DOK3 Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DOK3 (C-term) antibody

Formalin fixed and paraffin embedded human lung tissue reacted with DOK3 Antibody (C-term) Cat.-No AP51307PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DOK3 antibody

DOK3 MaxPab polyclonal antibody. Western Blot analysis of DOK3 expression in human liver. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

DOK3 antibody

DOK3 MaxPab polyclonal antibody. Western Blot analysis of DOK3 expression in human liver. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

DOK3 antibody

DOK3 polyclonal antibody ( Cat # PAB6065 ) staining ( 1 µg/ml ) of human PBMCs lysate ( RIPA buffer, 35 µg total protein per lane ) . Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

DOK3 antibody

Western blot analysis of extracts from HepG2 cells, using DOK3 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €205.00
  Assay Biotech

DOK3 antibody

Western blot analysis of extracts from HepG2 cells, using DOK3 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €310.00
  Assay Biotech

DOK3 antibody

NB 100-838 staining (0.5µg/ml) of Mouse Kidney extracts (RIPA buffer, 35µg total protein per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

DOK3 antibody

DOK3 Rabbit IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

DOK3 antibody

DOK3 Rabbit IgG Aff - Purified Hu, Ms E, WB
50 µg / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DOK3 (transcript variant 1)

DOK3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

DOK3

DOK3 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

DOK3 293T Cell Transient Overexpression Lysate(Denatured)

DOK3 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

DOK3 overexpression lysate

DOK3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

20 Item(s)

per page
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