DOK5 antibody

Principal name

DOK5 antibody

Alternative names for DOK5 antibody

Docking protein 5, IRS6, C20orf180, Downstream of tyrosine kinase 5, Insulin receptor substrate 6

SwissProt ID

Q91ZM9 (Mouse), Q9P104 (Human)

Gene ID

55816 (DOK5)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken), Por (Porcine), Can (Canine), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C)

Background of DOK5 antibody

The downstream of kinase family (Dok-1-7) are members of a class of “docking” proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4 and Dok-5 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK). Dok-5 transcript is abundant in muscle and increases during T cell activation. Dok-5 protein undergoes tyrosine phosphorylation in response to Insulin and Insulin-like growth factor-1. The gene encoding human Dok-5 maps to chromosomal location 20q13.2.

General readings

Liu, X., et al. J Am Acad Child Adolesc Psychiatry 49(1):33-41 (2010).
Tabassum, R., et al. BMC Med. Genet. 11, 35 (2010).
Shi, L., et al. Cell. Signal. 18(11):1995-2003 (2006).
Cai, D., et al. J. Biol. Chem. 278(28):25323-25330 (2003).
Favre, C., et al. Genes Immun. 4(1):40-45 (2003).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DOK5 (C-term) antibody

TA302468 (0.1µg/ml) staining of human kidney lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DOK5 antibody

Predicted cell location: Nucleus. Positive control: Human colon cancer tissue. Recommended dilution: 1/10-50  The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using DOK5 antibody at dilution 1/20, on the right is treated with the fusion protein. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

DOK5 antibody

Western blot analysis of extracts from K562 cells, using DOK5 antibody. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DOK5 antibody

WB Suggested Anti-DOK5 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human Placenta Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

DOK5 (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DOK5 (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DOK5 (PTB Dom.) antibody

Western blot analysis of Dok5 (arrow) using DOK5 Antibody (PTB domain) Cat.-No AP51308PU-N. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Dok5 gene. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DOK5 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with DOK5 polyclonal antibody ( Cat # PAB3409 ) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu, Ms E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

DOK5 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with DOK5 polyclonal antibody ( Cat # PAB3410 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu, Ms E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

DOK5 antibody

DOK5 polyclonal antibody ( Cat # PAB6689 ) ( 1 µg/ml ) staining of paraffin embedded human Tonsil. Microwaved antigen retrieval with citrate buffer pH6, HRP-staining. Goat Hu E, P, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

DOK5 antibody

Human Placenta; WB Suggested Anti-DOK5 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Placenta; DOK5 antibody - N-terminal region (ARP42518_P050) in Human Placenta cells using Western Blot Rabbit Aff - Purified Bov, Chk, Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

DOK5 antibody

Western blot analysis of DOK5 expression in HEK293T (A) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Mky, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

DOK5 antibody

Western blot analysis of DOK5 expression in HEK293T (A) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Mky, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

DOK5 antibody

Western blot analysis of DOK5 expression in HEK293T (A) whole cell lysates. Rabbit Aff - Purified Bov, Hu, Mky, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

DOK5 antibody

Immunohistochemistry: DOK5 Antibody [NB100-1463] - NB100-1463 (1ug/ml) staining of paraffin embedded Human Tonsil. Microwaved antigen retrieval with citrate buffer pH6, HRP-staining. Goat IgG Aff - Purified Hu E, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

DOK5 antibody

DOK5 Rabbit IgG Hu WB
0.1 ml / €340.00
  Novus Biologicals Inc.

DOK5 antibody

Western Blot: DOK5 Antibody [NBP1-56411] - This Anti-DOK5 antibody was used in Western Blot of Placenta tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Bov, Chk, Hu, Ms, Por, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DOK5

DOK5 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

DOK5

DOK5 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

DOK5

DOK5 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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