Dopamine D1 receptor antibody

Principal name

Dopamine D1 receptor antibody

Alternative names for Dopamine D1 receptor antibody

DRD1, D(1A) dopamine receptor

SwissProt ID

O02664 (Rabit), P18901 (Rat), P21728 (Human), P42289 (Xenla), P50130 (Pig), Q61616 (Mouse), Q95136 (Bovin)

Gene ID

1812 (DRD1), 24316 (Drd1a), 13488

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Can (Canine), Bt (Bat), Bov (Bovine), Hst (Hamster), Mky (Monkey), Por (Porcine), Gorilla, Rb (Rabbit), Sh (Sheep)

Available hosts

Rabbit, Mouse, Goat

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F), Dot blot (Dot), Immunoprecipitation (IP)

Background of Dopamine D1 receptor antibody

The D1 Dopamine Receptor (D1 Receptor) is one of five receptors that mediate the effects of the catecholamine neurotransmitter dopamine. Dopamine regulates a variety of functions including locomotor activity, emotion, positive reinforcement, food intake, and hormone secretion. The dopaminergic system has been extensively studied in the last thirty years mainly because its dysregulation has been linked to several neurological and neuropsychiatric diseases including Parkinson’s disease and schizophrenia. All five dopamine receptors belong to the 7-transmembrane domain, G-Protein Coupled Receptor (GPCR) superfamily. Historically, the five receptors have been divided into two subfamilies based on pharmacological and structural considerations: the D1-like subfamily (that includes the D1 and D5 subtypes) and the D2-like subfamily (that includes the D2-, D3- and D4 subtypes). The D1-like Receptors are coupled to Gs-type G proteins and enhance adenylate cyclase activity while the D2-like Receptors are coupled to Gi-type G proteins and inhibit adenylate cyclase activity. The D1 Receptor is widely distributed throughout the brain with the highest expression in the cerebral cortex and striatum. In the periphery the D1 Receptor has been detected in the adrel cortex, kidney and heart. Functiolly, the D1 Receptor has been implicated in the regulation of both locomotor and cognitive functions including the maintaining of spontaneous motor behaviors, the control of working memory and cognition as well as the regulation of craving and reward pathways. In addition, D1 Receptor plays an important role in the pathogenesis of hypertension by regulating epithelial + transport and by interacting with vasoactive hormones/humoral factors, such as aldosterone and angiotensin.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Dopamine D1 receptor (Cytopl. Dom.) antibody

Anti-Dopamine Receptor D1 / DRD1 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 8 ug/ml. Rabbit Aff - Purified Hu, Ms, Rt P
50 µg / €345.00
  OriGene Technologies, Inc.

Dopamine D1 receptor (C-term) antibody

Anti-Dopamine Receptor D1 / DRD1 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 7 ug/ml. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P
50 µg / €345.00
  OriGene Technologies, Inc.

Dopamine D1 receptor (C-term, Cytopl. Dom.) antibody

Anti-DRD1 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Elephant, Hst, Hu, Mky, Ms, Op, Por, Prim, Rb, Rt, Sh E, P
50 µg / €345.00
  OriGene Technologies, Inc.

Dopamine D1 receptor antibody

Anti-DRD1 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Hu, Mky
50 µg / €345.00
  OriGene Technologies, Inc.

Dopamine D1 receptor antibody

Gel: 10%SDS-PAGE, Lysate: 30 µg, Lane: Hela cells, Primary antibody:DRD1 Antibody at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Dopamine D1 receptor antibody

Gel: 10%SDS-PAGE, Lysate: 30 µg, Lane: Hela cells, Primary antibody: DRD1 Antibody at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Dopamine D1 receptor antibody

Western blot analysis of extracts of HeLa cell line, using DRD1 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Dopamine D1 receptor antibody

Western blot analysis of mouse (lanes 1 and 3) and rat (lanes 2 and 4) brain lysates: 1, 2. Anti-D1 Dopamine Receptor antibody, (1:200). 3, 4. Anti-D1 Dopamine Receptor antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Dopamine D1 receptor Control Peptide

Dopamine D1 receptor
0.25 mg / €250.00
  Acris Antibodies GmbH

Dopamine D1 receptor (N-term) antibody

Dopamine D1 receptor Rabbit Aff - Purified Rt Dot, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Dopamine D1 receptor Control Peptide

Dopamine D1 receptor
0.25 mg / €250.00
  Acris Antibodies GmbH

Dopamine D1 receptor (internal) antibody

Dopamine D1 receptor Rabbit Aff - Purified Rt Dot, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Dopamine D1 receptor Control Peptide

Dopamine D1 receptor
0.25 mg / €250.00
  Acris Antibodies GmbH

Dopamine D1 receptor (C-term) antibody

Dopamine D1 receptor Rabbit Aff - Purified Ms, Rt Dot, WB
0.25 mg / €420.00
  Acris Antibodies GmbH

Dopamine D1 receptor (C-term) antibody

DRD1 Polyclonal Antibody Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Dopamine D1 receptor antibody

Dopamine D1 receptor Rabbit Serum Hu, Rt C, E, ICC/IF, WB
0.1 ml / €520.00
  Acris Antibodies GmbH

Dopamine D1 receptor antibody

Detection of Drd1a of Sf9 cells transfected with rat Drd1a using Drd1a monoclonal antibody, clone SG2-D1a ( Cat # MAB2314 ).
Lane 1 : Sf9-Drd5 lysate.
Lane 2 : Sf9-Drd1a lyate.
Please note that these results are similiar to those shown in J. Neuroimmunol. 101 : 170-187 publication. Mouse IgG2b SG2-D1a Ms, Rt ICC/IF, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

Dopamine D1 receptor antibody

Dopamine D1 receptor Goat Hu, Ms, Rt E
0.1 mg / €390.00
  Abnova Taiwan Corp.

Dopamine D1 receptor antibody

Western blot of Drd1a polyclonal antibody ( Cat # PAB8946 ) with protein-coupled Drd1a samples. Rabbit Hu, Ms, Rt C, Dot, E, IP, WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

Dopamine D1 receptor (C-term) antibody

Western Blot analysis of DRD1 expression from cell extracts with DRD1 polyclonal antibody ( Cat # PAB12318 ).
Lane 1 : rat brain tissue lysate.
Lane 2 : rat brain tissue lysate. Rabbit Hu, Ms, Rt WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

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