Dopamine D1 receptor antibody

Principal name

Dopamine D1 receptor antibody

Alternative names for Dopamine D1 receptor antibody

DRD1, D(1A) dopamine receptor

SwissProt ID

O02664 (Rabit), P18901 (Rat), P21728 (Human), P42289 (Xenla), P50130 (Pig), Q61616 (Mouse), Q95136 (Bovin)

Gene ID

24316 (Drd1a), 1812 (DRD1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bt (Bat), Bov (Bovine), Hst (Hamster), Mky (Monkey), Op (Opossum), Por (Porcine), Prim (Primate), Rb (Rabbit), Sh (Sheep), Bear

Available hosts

Rabbit, Mouse, Goat

Available applications

Frozen Sections (C), Dot blot (Dot), Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of Dopamine D1 receptor antibody

The D1 Dopamine Receptor (D1 Receptor) is one of five receptors that mediate the effects of the catecholamine neurotransmitter dopamine. Dopamine regulates a variety of functions including locomotor activity, emotion, positive reinforcement, food intake, and hormone secretion. The dopaminergic system has been extensively studied in the last thirty years mainly because its dysregulation has been linked to several neurological and neuropsychiatric diseases including Parkinson’s disease and schizophrenia. All five dopamine receptors belong to the 7-transmembrane domain, G-Protein Coupled Receptor (GPCR) superfamily. Historically, the five receptors have been divided into two subfamilies based on pharmacological and structural considerations: the D1-like subfamily (that includes the D1 and D5 subtypes) and the D2-like subfamily (that includes the D2-, D3- and D4 subtypes). The D1-like Receptors are coupled to Gs-type G proteins and enhance adenylate cyclase activity while the D2-like Receptors are coupled to Gi-type G proteins and inhibit adenylate cyclase activity. The D1 Receptor is widely distributed throughout the brain with the highest expression in the cerebral cortex and striatum. In the periphery the D1 Receptor has been detected in the adrel cortex, kidney and heart. Functiolly, the D1 Receptor has been implicated in the regulation of both locomotor and cognitive functions including the maintaining of spontaneous motor behaviors, the control of working memory and cognition as well as the regulation of craving and reward pathways. In addition, D1 Receptor plays an important role in the pathogenesis of hypertension by regulating epithelial + transport and by interacting with vasoactive hormones/humoral factors, such as aldosterone and angiotensin.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Dopamine D1 receptor antibody

  Rabbit polyclonal anti-DRD1 antibody  
Western blot analysis of extracts from HepG2 cells, using DRD1 Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Dopamine D1 receptor (Cytopl. Dom.) antibody

  Dopamine Receptor D1 / DRD1 Rabbit Polyclonal (Cytoplasmic Domain) Antibody  
Anti-Dopamine Receptor D1 / DRD1 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 8 ug/ml. Rabbit Aff - Purified Hu, Ms, Rt P
50 µg / €400.00
  OriGene Technologies, Inc.

Dopamine D1 receptor (C-term) antibody

  Dopamine Receptor D1 / DRD1 Rabbit Polyclonal (C-Terminus) Antibody  
Anti-Dopamine Receptor D1 / DRD1 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 7 ug/ml. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P
50 µg / €400.00
  OriGene Technologies, Inc.

Dopamine D1 receptor (C-term, Cytopl. Dom.) antibody

  Dopamine Receptor D1 / DRD1 Rabbit Polyclonal (C-Terminus) Antibody  
Anti-DRD1 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Elephant, Hst, Hu, Mky, Ms, Op, Por, Prim, Rb, Rt, Sh E, P
50 µg / €400.00
  OriGene Technologies, Inc.

Dopamine D1 receptor antibody

  Dopamine Receptor D1 / DRD1 Rabbit Polyclonal (Extracellular Domain) Antibody  
Anti-DRD1 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Hu, Mky
50 µg / €400.00
  OriGene Technologies, Inc.

Dopamine D1 receptor antibody

  Anti-DRD1 Rabbit Polyclonal Antibody  
Gel: 10%SDS-PAGE, Lysate: 30 µg, Lane: Hela cells, Primary antibody:DRD1 Antibody at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Dopamine D1 receptor antibody

  Anti-DRD1 Rabbit Polyclonal Antibody  
Gel: 10%SDS-PAGE, Lysate: 30 µg, Lane: Hela cells, Primary antibody: DRD1 Antibody at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Dopamine D1 receptor antibody

  Rabbit anti-DRD1 Polyclonal Antibody  
Western blot analysis of extracts of HeLa cell line, using DRD1 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Dopamine D1 receptor antibody

  Rabbit Polyclonal Anti-D1 Dopamine Receptor  
Western blot analysis of mouse (lanes 1 and 3) and rat (lanes 2 and 4) brain lysates: 1, 2. Anti-D1 Dopamine Receptor antibody, (1:200). 3, 4. Anti-D1 Dopamine Receptor antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Dopamine D1 receptor (C-term) antibody

DRD1 Polyclonal Antibody Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Dopamine D1 receptor antibody

Dopamine D1 receptor Rabbit Serum Hu, Rt C, E, ICC/IF, WB
0.1 ml / €560.00
  Acris Antibodies GmbH

Dopamine D1 receptor antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using DRD1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P
50 µg / €230.00
  Assay Biotech

Dopamine D1 receptor antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using DRD1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

DRD1 - human gene knockout kit via CRISPR

DRD1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

DRD1 - human gene knockout kit via CRISPR

DRD1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

DRD1 - human gene knockout kit via CRISPR

DRD1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

DRD1 - human gene knockout kit via CRISPR

DRD1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

DRD1 overexpression lysate

DRD1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, DRD1 (mGFP-tagged) - Human dopamine receptor D1 (DRD1), 200 uL, >10^7 TU/mL

Lenti ORF particles, DRD1 (mGFP-tagged) - Human dopamine receptor D1 (DRD1), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, DRD1 (Myc-DDK tagged) - Human dopamine receptor D1 (DRD1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, DRD1 (Myc-DDK tagged) - Human dopamine receptor D1 (DRD1) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

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