Dopamine D2 receptor antibody

Principal name

Dopamine D2 receptor antibody

Alternative names for Dopamine D2 receptor antibody

DRD2, D(2) dopamine receptor

SwissProt ID

P14416 (Human), P20288 (Bovin), P61168 (Mouse), P61169 (Rat), Q9GJU1 (Canfa)

Gene ID

1813 (DRD2), 24318 (Drd2)

Available reactivities

Hu (Human), Rt (Rat), Bt (Bat), Bov (Bovine), Can (Canine), Eq (Equine), Ft (Ferret), Hst (Hamster), Mky (Monkey), Ms (Mouse), Por (Porcine), Rb (Rabbit), Bear, All Species, Gorilla, Chimp (Chimpanzee)

Available hosts

Rabbit, Mouse

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Dot blot (Dot), Immunoprecipitation (IP)

Background of Dopamine D2 receptor antibody

The D2 Dopamine Receptor (D2 receptor) is one of five receptors that mediate the effects of the catecholamine neurotransmitter dopamine. Dopamine regulates a variety of functions including locomotor activity, emotion, positive reinforcement, food intake, and endocrine regulation. The dopaminergic system has been extensively studied in the last thirty years mainly because its dysregulation has been linked to several neurological and neuropsychiatric diseases including Parkinsonâ??s disease and schizophrenia.All five dopamine receptors belong to the 7-transmembrane domain, G protein-coupled receptor (GPCR) superfamily.Historically, the five receptors have been divided into two subfamilies based on pharmacological and structural considerations: the D1-like subfamily (that includes the D1 and D5 subtypes) and the D2-like subfamily (that includes the D2-, D3- and D4 subtypes).The D1-like receptors are coupled to Gs-type G proteins and enhance adenylate cyclase activity while the D2-like receptors are coupled to Gi-type G proteins and inhibit adenylate cyclase activity.D2 receptor expression in the brain is largely confined to the striatum, prefrontal cortex and hypothalamus.Dysregulation of the D2 receptor function has been implicated in several disorders including schizophrenia, bipolar disorder, Parkinson's disease, and restless legs syndrome. Consistent with this, treatments that either block or activate D2 receptor have been developed to treat these diseases.

General readings

Verma, V., et al. J. Biol. Chem. 285(45):35092-35103(2010)
Borroto-Escuela, D.O., et al. Biochem. Biophys. Res. Commun. 401(4):605-610(2010)
Stelzel, C., et al. J. Neurosci. 30(42):14205-14212(2010)
Huang, H.Y., et al. J. Formos. Med. Assoc. 109(10):736-739(2010)
Itokawa, M., et al. J. Pharmacol. Sci. 114(1):1-5(2010)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Dopamine D2 receptor (Short Isoform, 239-246) antibody

Dopamine D2 receptor Rabbit Serum Rt C, E, ICC/IF, WB
0.1 ml / €520.00
  Acris Antibodies GmbH

Dopamine D2 receptor (3rd Cytopl. Dom.) antibody

Anti-DRD2 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Ft, Hst, Hu, Mky, Ms, Por, Rb, Rt P
50 µg / €345.00
  OriGene Technologies, Inc.

Dopamine D2 receptor (3rd cytopl. dom.) antibody

Anti-DRD2 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Ft, Hu, Mky, Por, Rb P
50 µg / €345.00
  OriGene Technologies, Inc.

Dopamine D2 receptor antibody

Western blot analysis of rat striatum (lanes 1 and 5) and hippocampus (lanes 2 and 6) membranes and of rat (lanes 3 and 7) and mouse (lanes 4 and 8) whole brain lysates: 1-4. Anti-D2 Dopamine Receptor (extracellular) antibody, (1:200). 5-8. Anti-D2 Dopamine Receptor (extracellular), preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Dopamine D2 receptor antibody

Dopamine D2 receptor Mouse IgG1 N186/29 Supernatant Ms, Rt WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

Dopamine D2 receptor antibody

Dopamine D2 receptor Mouse IgG1 N186/29 Purified Ms, Rt WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

Dopamine D2 receptor Control Peptide

Dopamine D2 receptor Ms
0.25 mg / €250.00
  Acris Antibodies GmbH

Dopamine D2 receptor (N-term) antibody

Western blot under reducing conditions using D2R Antibody Cat.-No AP09965PU-N: Lane 1, 65 µg Rat striatal membrane Protein, 
Lane 2: 65 µg cerebellar membrane proteins. Apparent MW of D2R is 110kDa upper band and 45kDa lower band. Rabbit Aff - Purified Hu, Ms, Rt C, Dot, E, IP, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Dopamine D2 receptor Control Peptide

Dopamine D2 receptor Ms
0.25 mg / €250.00
  Acris Antibodies GmbH

Dopamine D2 receptor (C-term) antibody

Dopamine D2 receptor Rabbit Aff - Purified Hu, Ms, Rt C, E, ICC/IF, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Dopamine D2 receptor (C-term) antibody

Western blot analysis of Dopamine D2 receptor Antibody (C-term) Cat.-No AP51318PU-N in mouse NIH-3T3 cell line lysates (35ug/lane). This demonstrates the DRD2 antibody detected the DRD2 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Dopamine D2 receptor (long isoform, 243-254) antibody

Dopamine D2 receptor Rabbit Serum Hu, Rt C, E, ICC/IF, WB
0.1 ml / €520.00
  Acris Antibodies GmbH

Dopamine D2 receptor antibody

Dopamine D2 receptor Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

Dopamine D2 receptor antibody

Dopamine D2 receptor Rabbit IgG Serum All Species E, ICC/IF, WB
50 µl / €440.00
  Novus Biologicals Inc.

Dopamine D2 receptor antibody

Brain, Neurons and Glia Rabbit Aff - Purified Hu P
50 µl / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Dopamine D2 receptor

Dopamine D2 receptor Human
10 µg / €540.00
  Abnova Taiwan Corp.

Dopamine D2 receptor

Dopamine D2 receptor Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Dopamine D2 receptor

Dopamine D2 receptor Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

18 Item(s)

per page
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