Dopamine D3 Receptor antibody

Principal name

Dopamine D3 Receptor antibody

Alternative names for Dopamine D3 Receptor antibody

DRD3, D3DR, ETM1, FET1, D(3) Dopamine receptor, Dopamin receptor D3

SwissProt ID

P19020 (Rat), P30728 (Mouse), P35462 (Human), Q5IS72 (Pantr)

Gene ID

29238 (Drd3), 1814 (DRD3), 13490

Available reactivities

Rt (Rat), Bt (Bat), Bov (Bovine), Can (Canine), Eq (Equine), Hst (Hamster), Hu (Human), Ms (Mouse), Op (Opossum), Por (Porcine), Rb (Rabbit), Bear, Mky (Monkey), Gorilla, Chimp (Chimpanzee)

Available hosts

Rabbit, Mouse

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Dot blot (Dot), Immunoprecipitation (IP), Flow Cytometry (F)

Background of Dopamine D3 Receptor antibody

The D3 Dopamine Receptor (D3 receptor) is one of five receptors that mediate the effects of the catecholamine neurotransmitter dopamine. Dopamine regulates a variety of functions including locomotor activity, emotion, positive reinforcement, food intake, and endocrine regulation. The dopaminergic system has been extensively studied in the last thirty years mainly because its dysregulation has been linked to several neurological and neuropsychiatric diseases including Parkinsonâ??s disease and schizophrenia. All five dopamine receptors belong to the 7-transmembrane domain, G protein-coupled receptor (GPCR) superfamily. Historically, the five receptors have been divided into two subfamilies based on pharmacological and structural considerations: the D1-like subfamily (that includes the D1 and D5 subtypes) and the D2-like subfamily (that includes the D2-, D3- and D4 subtypes). The D1-like receptors are coupled to Gs-type G proteins and enhance adenylate cyclase activity while the D2-like receptors are coupled to Gi-type G proteins and inhibit adenylate cyclase activity. The D3 receptor distribution in the brain is relatively restricted to limbic areas such as striatum, islands of Calleja and olfactory tubercle. In the periphery, it is expressed in the kidney particularly in proximal tubules. The exact physiological function of the D3 receptor remains to be fully elucidated. In studies using D3 receptor knockout mice, the most prominent dysfunction was the development of rennin-dependent hypertension. Potential roles in reinforcement and reward behaviors have also been suggested as well as roles in neuropsychiatric disorders such as drug abuse and schizophrenia.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Dopamine D3 Receptor (3rd Cytopl. Dom.) antibody

Anti-DRD3 / Dopamine Receptor D3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Hst, Hu, Ms, Op, Por, Rb, Rt E, P
50 µg / €345.00
  OriGene Technologies, Inc.

Dopamine D3 Receptor antibody

Anti-DRD3 / Dopamine Receptor D3 antibody IHC of human brain, globus pallidus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Can, Chimp, Eq, Hst, Hu, Mky, Ms, Por, Rb
50 µg / €345.00
  OriGene Technologies, Inc.

Dopamine D3 Receptor antibody

Western blot analysis of rat whole brain (lanes 1 and 3) and striatum (lanes 2 and 4) membranes: 1, 2. Anti-D3 Dopamine Receptor (extracellular) antibody , (1:200). 3, 4. Anti-D3 Dopamine Receptor (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Dopamine D3 Receptor antibody

Transfected cell immunofluorescence: COS cells expressing untagged human Dopamine D3 receptor with GFP. Red = N331/10, Green = GFP, Blue = Hoechst nuclear stain. Mouse IgG2a N331/19 Supernatant Hu ICC/IF
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

Dopamine D3 Receptor Control Peptide

Dopamine D3 Receptor
0.25 mg / €250.00
  Acris Antibodies GmbH

Dopamine D3 Receptor (N-term) antibody

Western blot using AP09967PU-N (1:750). Rabbit Aff - Purified Hu, Ms, Rt Dot, E, IP, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Dopamine D3 Receptor antibody

Dopamine D3 Receptor Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

Dopamine D3 Receptor antibody

Dopamine D3 Receptor Rabbit Aff - Purified Hu P
50 µg / €440.00
  Novus Biologicals Inc.

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