Dopamine D5 receptor antibody

Principal name

Dopamine D5 receptor antibody

Alternative names for Dopamine D5 receptor antibody

DRD5, D5DR, DRD1B, DRD1L2, D1B, D(1B) Dopamine receptor, D1beta Dopamine receptor, D(5) Dopamine receptor, Dopamine receptor D5

SwissProt ID

P21918 (Human), P25115 (Rat), Q8BLD9 (Mouse), Q95137 (Bovin)

Gene ID

1816 (DRD5), 25195 (Drd5), 13492

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Can (Canine), Eq (Equine), Mky (Monkey), Gorilla

Available hosts

Goat, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Dot blot (Dot)

Background of Dopamine D5 receptor antibody

The D5 Dopamine Receptor (D5 receptor) is one of five receptors that mediate the effects of the catecholamine neurotransmitter dopamine. Dopamine regulates a variety of functions including locomotor activity, emotion, positive reinforcement, food intake, and hormone secretion. The dopaminergic system has been extensively studied in the last thirty years mainly because its dysregulation has been linked to several neurological and neuropsychiatric diseases including Parkinson’s disease and schizophrenia. All five dopamine receptors belong to the 7-transmembrane domain, G protein-coupled receptor (GPCR) superfamily. Historically, the five receptors have been divided into two subfamilies based on pharmacological and structural considerations: the D1-like subfamily (that includes the D1 and D5 subtypes) and the D2-like subfamily (that includes the D2-, D3- and D4 subtypes). The D1-like receptors are coupled to Gs-type G proteins and enhance adenylate cyclase activity while the D2-like receptors are coupled to Gi-type G proteins and inhibit adenylate cyclase activity. The D5 receptor is widely distributed throughout the brain with the highest expression in the cerebral cortex, hippocampus and striatum. In the periphery the D5 receptor has been localized in the adrel cortex, kidney and intestil tract. The exact physiological function of the D5 receptor subtype remains poorly understood. Studies with D5 receptor knock out mice have shown no overt alterations in locomotor or cognitive functions. However, knock out mice do develop severe hypertension suggesting a role of D5 receptor in the modulation of neurol pathways regulating blood pressure responses.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Dopamine D5 receptor antibody

  DRD5 / Dopamine Receptor D5 Rabbit Polyclonal (Cytoplasmic Domain) Antibody  
Anti-DRD5 / Dopamine Receptor D5 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Can, Eq, Gorilla, Hu, Mky
50 µg / €400.00
  OriGene Technologies, Inc.

Dopamine D5 receptor (3rd extrac. dom.) antibody

  DRD5 / Dopamine Receptor D5 Rabbit Polyclonal (Extracellular Domain) Antibody  
Anti-DRD5 / Dopamine Receptor D5 antibody IHC of rat brain, Purkinje neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Aff - Purified Hu, Mky P
50 µg / €400.00
  OriGene Technologies, Inc.

Dopamine D5 receptor antibody

  Anti-DRD5 rabbit polyclonal antibody  
Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane: Human ovarian cancer tissue, Primary antibody:DRD5 Antibody at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Dopamine D5 receptor antibody

  Rabbit anti-DRD5 Polyclonal Antibody  
Western blot analysis of extracts of mouse brain tissue cell , using DRD5 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Dopamine D5 receptor antibody

  Rabbit Polyclonal Anti-D5 Dopamine Receptor (extracellular)  
Western blot analysis of mouse brain membranes: 1. Anti-D5 Dopamine Receptor (extracellular) antibody, (1:200). 2. Anti-D5 Dopamine Receptor (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Dopamine D5 receptor antibody

  Rabbit Polyclonal anti-D5DR Antibody  
Human Brain stained with anti-D5DR antibody. Rabbit IgG Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

DRD5 - human gene knockout kit via CRISPR

DRD5 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

DRD5 - human gene knockout kit via CRISPR

DRD5 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

DRD5 - human gene knockout kit via CRISPR

DRD5 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

DRD5 - human gene knockout kit via CRISPR

DRD5 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Drd5 - mouse gene knockout kit via CRISPR

Drd5 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Drd5 - mouse gene knockout kit via CRISPR

Drd5 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Drd5 - mouse gene knockout kit via CRISPR

Drd5 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Drd5 - mouse gene knockout kit via CRISPR

Drd5 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

DRD5 overexpression lysate

DRD5 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, DRD5 (Myc-DDK tagged) - Human dopamine receptor D5 (DRD5) , 200 uL, >10^7 TU/mL

Lenti ORF particles, DRD5 (Myc-DDK tagged) - Human dopamine receptor D5 (DRD5) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Drd5 (GFP-tagged) - Mouse dopamine receptor D5 (Drd5), 200 uL, >10^7 TU/mL

Lenti ORF particles, Drd5 (GFP-tagged) - Mouse dopamine receptor D5 (Drd5), 200 uL, >10^7 TU/mL  
200 µl / €1,080.00
  OriGene Technologies, Inc.

Lenti ORF particles, Drd5 (Myc-DDK-tagged) - Mouse dopamine receptor D5 (Drd5), 200 uL, >10^7 TU/mL

Lenti ORF particles, Drd5 (Myc-DDK-tagged) - Mouse dopamine receptor D5 (Drd5), 200 uL, >10^7 TU/mL  
200 µl / €970.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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