Doublecortin-like kinase 1 antibody

Principal name

Doublecortin-like kinase 1 antibody

Alternative names for Doublecortin-like kinase 1 antibody

DCLK, DCKL1, DCAMKL1, DCDC3A, CLICK1, KIAA0369, Serine/threonine-protein kinase DCLK1

SwissProt ID

O08875 (Rat), O15075 (Human), Q9JLM8 (Mouse)

Gene ID

9201 (DCLK1), 13175 (Dclk1), 83825

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Paraffin Sections (P)

Background of Doublecortin-like kinase 1 antibody

This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Doublecortin-like kinase 1 antibody

  Rabbit Polyclonal DCLK1 Antibody  
Western blot analysis of DCLK1 in human brain tissue lysate with DCLK1 antibody at (A) 0.5 and (B) 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Doublecortin-like kinase 1 antibody

  Rabbit Polyclonal Anti-DCLK1 Antibody  
Host: Rabbit; Target Name: DCLK1; Sample Tissue: 721_B Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Doublecortin-like kinase 1 antibody

  Rabbit Polyclonal Anti-DCLK1 Antibody  
Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane: Mouse brain tissue, Primary antibody: (DCLK1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Doublecortin-like kinase 1 antibody

  Rabbit Polyclonal Anti-DCLK1 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using (DCLK1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Doublecortin-like kinase 1 (N-term) antibody

Western blot analysis of DCAMKL1 Antibody (N-term)(AP13897PU-N) in mouse brain tissue lysate. DCAMKL1 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Doublecortin-like kinase 1 (C-term) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with DCAMKL1 Antibody (C-term) (AP13898PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Dclk1 - mouse gene knockout kit via CRISPR

Dclk1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Dclk1 - mouse gene knockout kit via CRISPR

Dclk1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dclk1 - mouse gene knockout kit via CRISPR

Dclk1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dclk1 - mouse gene knockout kit via CRISPR

Dclk1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Doublecortin-like kinase 1

  Recombinant protein of human doublecortin-like kinase 1 (DCLK1)  
Doublecortin-like kinase 1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Doublecortin-like kinase 1 (transcript variant 3)

  Purified recombinant protein of Homo sapiens doublecortin-like kinase 1 (DCLK1), transcript variant 3.  
Doublecortin-like kinase 1 Human > 80 %
Preparation: or Add: Recombint proteins was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, DCLK1 (mGFP-tagged)-Human doublecortin-like kinase 1 (DCLK1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, DCLK1 (mGFP-tagged)-Human doublecortin-like kinase 1 (DCLK1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,010.00
  OriGene Technologies, Inc.

Lenti ORF particles, DCLK1 (mGFP-tagged) - Human doublecortin-like kinase 1 (DCLK1), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, DCLK1 (mGFP-tagged) - Human doublecortin-like kinase 1 (DCLK1), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,030.00
  OriGene Technologies, Inc.

Lenti ORF particles, DCLK1 (mGFP-tagged)-Human doublecortin-like kinase 1 (DCLK1), transcript variant 4, 200 uL, >10^7 TU/mL

Lenti ORF particles, DCLK1 (mGFP-tagged)-Human doublecortin-like kinase 1 (DCLK1), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, DCLK1 (Myc-DDK-tagged)-Human doublecortin-like kinase 1 (DCLK1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, DCLK1 (Myc-DDK-tagged)-Human doublecortin-like kinase 1 (DCLK1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €900.00
  OriGene Technologies, Inc.

Lenti ORF particles, DCLK1 (Myc-DDK tagged) - Human doublecortin-like kinase 1 (DCLK1), transcript variant 3 , 200 uL, >10^7 TU/mL

Lenti ORF particles, DCLK1 (Myc-DDK tagged) - Human doublecortin-like kinase 1 (DCLK1), transcript variant 3 , 200 uL, >10^7 TU/mL  
200 µl / €920.00
  OriGene Technologies, Inc.

Lenti ORF particles, DCLK1 (Myc-DDK-tagged)-Human doublecortin-like kinase 1 (DCLK1), transcript variant 4, 200 uL, >10^7 TU/mL

Lenti ORF particles, DCLK1 (Myc-DDK-tagged)-Human doublecortin-like kinase 1 (DCLK1), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Dclk1 (GFP-tagged) - Mouse doublecortin-like kinase 1 (Dclk1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Dclk1 (GFP-tagged) - Mouse doublecortin-like kinase 1 (Dclk1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,460.00
  OriGene Technologies, Inc.

Lenti ORF particles, Dclk1 (GFP-tagged) - Mouse doublecortin-like kinase 1 (Dclk1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Dclk1 (GFP-tagged) - Mouse doublecortin-like kinase 1 (Dclk1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,030.00
  OriGene Technologies, Inc.

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