DPYSL2 / CRMP2 antibody

Principal name

DPYSL2 / CRMP2 antibody

Alternative names for DPYSL2 / CRMP2 antibody

Dihydropyrimidinase-related protein 2, DRP-2, N2A3, Collapsin response mediator protein 2

SwissProt ID

O02675 (Bovin), O08553 (Mouse), P47942 (Rat), Q16555 (Human), Q90635 (Chick)

Gene ID

25416 (Dpysl2), 1808 (DPYSL2), 12934

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse), Chk (Chicken), Bov (Bovine), Can (Canine), Ze (Zebrafish), African clawed frog

Available hosts

Rabbit, Sheep, Mouse

Available applications

Frozen Sections (C), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of DPYSL2 / CRMP2 antibody

Collapsin response mediator proteins (CRMPs) are cytosolic phosphoproteins involved in neuronal differentiation and axonal guidance. CRMP2 was previously shown to mediate the repulsive effect of Sema3A on axons and to participate in axonal specification. The CRMPs appear to play a complex role in axon growth as well as microtubule dynamics and axon induction. CRMPs localize to the lamellipodia and filopodia of axonal growth cones, suggesting a role in axon guidance. Moreover, CRMP2 is upregulated after axotomy, and appears to increase the formation of axon-type processes from hippocampal neurons. CRMP2 has been reported to bind tubulin dimers directly and modulate microtubule assembly. CRMPs have also been implicated in the pathogenesis of a paraneoplastic neurologic syndrome. Interaction studies have implicated phospholipase D2 (PLD2), the cytosolic tyrosine kinase Fes, and intersectin in CRMP function. Hyperphosphorylation of CRMP2 is an early event in the progression of Alzheimer's disease.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DPYSL2 / CRMP2 (C-term) antibody

Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

DPYSL2 / CRMP2 antibody

Western blot analysis of extracts from HT-29 cells, treated with heat shock, using CRMP-2 (Ab-509) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DPYSL2 / CRMP2 antibody

Western blot analysis of extracts from HepG2 cells, Jurkatcells and 293 cells, using CRMP-2 (Ab-522)antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DPYSL2 / CRMP2 antibody

Western blot analysis of extracts from A549 cells, treated with EGF (200ng/ml, 30mins), using DRP-2 (Ab-514) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DPYSL2 / CRMP2 antibody

Predicted band size: 62kDa. Positive control: NIH/3T3 cell lysate . Recommended dilution: 1/200-1000 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DPYSL2 / CRMP2 antibody

Predicted cell location: Cytoplasm . Positive control: Human liver cancer tissue. Recommended dilution: 1/50-300  The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using DPYSL2 antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

DPYSL2 / CRMP2 antibody

Western blot analysis of DRP-2 expression in EGF treated A549 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DPYSL2 / CRMP2 antibody

Immunohistochemistry: AM11031SU-N DPYSL2 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Testis followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. Mouse IgG2b 33CT11.40.3 Ascites Hu P, WB
0.1 ml / €370.00
  Acris Antibodies GmbH

DPYSL2 / CRMP2 pSer465 antibody

DPYSL2 / CRMP2 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

DPYSL2 / CRMP2 antibody

Distribution patternof CRMP2 in olfactory receptor neurons within the olfactory mucosa Rabbit Serum Ms C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

DPYSL2 / CRMP2 pThr509 antibody

Immunohistochemical analysis of paraffin-embedded human brain tissue using CRMP-2 (Phospho-Thr509) antibody AP55813PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €340.00
  Acris Antibodies GmbH

DPYSL2 / CRMP2 pThr509 antibody

Immunohistochemical analysis of paraffin-embedded human brain tissue using CRMP-2 (Phospho-Thr509) antibody AP55813PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µl / €270.00
  Acris Antibodies GmbH

DPYSL2 / CRMP2 pSer522 antibody

Western blot analysis of extracts from HuvEc cells (Lane 2), using CRMP-2 (Phospho-Ser522) Antibody AP55854PU-N. The lane on the left is treated with antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €340.00
  Acris Antibodies GmbH

DPYSL2 / CRMP2 pSer522 antibody

Western blot analysis of extracts from HuvEc cells (Lane 2), using CRMP-2 (Phospho-Ser522) Antibody AP55854PU-N. The lane on the left is treated with antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µl / €270.00
  Acris Antibodies GmbH

DPYSL2 / CRMP2 antibody

DPYSL2 / CRMP2 Mouse IgG2a 1F11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

DPYSL2 / CRMP2 antibody

DPYSL2 / CRMP2 Rabbit Hu, Ms, Rt E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

DPYSL2 / CRMP2 pThr514 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using DRP-2 (Phospho-Thr514) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

DPYSL2 / CRMP2 pThr514 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using DRP-2 (Phospho-Thr514) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

DPYSL2 / CRMP2 pThr509 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using CRMP-2 (Phospho-Thr509) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €205.00
  Assay Biotech

DPYSL2 / CRMP2 pThr509 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using CRMP-2 (Phospho-Thr509) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €310.00
  Assay Biotech

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