Drebrin-like protein (DBNL) antibody

Principal name

Drebrin-like protein (DBNL) antibody

Alternative names for Drebrin-like protein (DBNL) antibody

Drebrin-F, CMAP, SH3P7, HIP-55, Cervical mucin-associated protein, SH3 domain-containing protein 7, HPK1-interacting protein of 55 kDa

SwissProt ID

A6H7G2 (Bovin), Q62418 (Mouse), Q9JHL4 (Rat), Q9UJU6 (Human)

Gene ID

28988 (DBNL), 13169 (Dbnl), 83527

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Rt (Rat), GP (Guinea Pig), Por (Porcine)

Available hosts

Goat, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Drebrin-like protein (DBNL) antibody

Cellular morphology, adhesion, and motility occur through dynamic reorganization of actin-based superstructures. Actin-binding proteins are critical for regulating actin polymerization and superstructure formation. The Arp2/3 complex is an actin polymerization-inducing complex that includes Arp2, Arp3, p41-Arc, p34-Arc, p21-Arc, p20 Arc, and p16-Arc. Several actin binding proteins, WASP, cortactin, and Abp1, regulate the activity of the Arp2/3 complex. HIP55 is the mammalian homologue of the yeast HIP55, which has been shown to bind actin and to have roles in endocytosis. HIP55 contains a C-terminal Src homology 3 domain and an N-terminal actin depolymerization factor (ADF-H/C) domain that is homologous to a similar domain found in the actin severing protein, cofilin. HIP55 can bind Src kinases, hematopoietic progenitor kinase 1 (HPK-1), myosin I heavy chain kinase, and dynamin. Thus, HIP55 may be important for regulation of the actin cytoskeleton through its ability to interact with F-actin and various other cytoskeletal and cell signaling proteins. There are three different isoforms.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Drebrin-like protein (DBNL) (N-term) antibody

  Goat Polyclonal Antibody against DBNL  
TA302793 staining (1µg/ml) of Jurkat lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Drebrin-like protein (DBNL) antibody

  Rabbit Polyclonal Anti-DBNL Antibody  
WB Suggested Anti-DBNL Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Muscle Rabbit IgG Purified Can, GP, Hu, Ms, Por WB
50 µg / €325.00
  OriGene Technologies, Inc.

Drebrin-like protein (DBNL) antibody

  DBNL mouse monoclonal antibody, clone OTI6C9 (formerly 6C9)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-DBNL mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805075) Mouse IgG1 OTI6C9 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Drebrin-like protein (DBNL) antibody

  DBNL mouse monoclonal antibody, clone OTI7B7 (formerly 7B7)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DBNL (RC203435, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DBNL. Mouse IgG1 OTI7B7 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CRISPR

Catalog No. Species Donor Vector  

DBNL - human gene knockout kit via CRISPR

DBNL - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

DBNL - human gene knockout kit via CRISPR

DBNL - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

DBNL - human gene knockout kit via CRISPR

DBNL - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

DBNL - human gene knockout kit via CRISPR

DBNL - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dbnl - mouse gene knockout kit via CRISPR

Dbnl - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Dbnl - mouse gene knockout kit via CRISPR

Dbnl - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dbnl - mouse gene knockout kit via CRISPR

Dbnl - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dbnl - mouse gene knockout kit via CRISPR

Dbnl - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Drebrin-like protein (DBNL) (transcript variant 1)

  Recombinant protein of human drebrin-like (DBNL), transcript variant 1  
Drebrin-like protein (DBNL) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Drebrin-like protein (DBNL) (transcript variant 2)

  Recombinant protein of human drebrin-like (DBNL), transcript variant 2  
Drebrin-like protein (DBNL) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Drebrin-like protein (DBNL) (full length, C-term DDK tag, transcript variant 1)

  Recombinant protein of human drebrin-like (DBNL), transcript variant 1, full length, with C-terminal DDK tag, expressed in sf9, 20ug  
Drebrin-like protein (DBNL) Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

DBNL overexpression lysate

DBNL overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

DBNL overexpression lysate

DBNL overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, DBNL (mGFP-tagged) - Human drebrin-like (DBNL), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, DBNL (mGFP-tagged) - Human drebrin-like (DBNL), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, DBNL (mGFP-tagged) - Human drebrin-like (DBNL), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, DBNL (mGFP-tagged) - Human drebrin-like (DBNL), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, DBNL (Myc-DDK tagged) - Human drebrin-like (DBNL), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, DBNL (Myc-DDK tagged) - Human drebrin-like (DBNL), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

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