DRG1 / NEDD3 antibody

Principal name

DRG1 / NEDD3 antibody

Alternative names for DRG1 / NEDD3 antibody

DRG-1, NEDD-3, Developmentally-regulated GTP-binding protein 1, Neural precursor cell expressed developmentally down-regulated protein 3

SwissProt ID

P32233 (Mouse), P43690 (Xenla), Q3MHP5 (Bovin), Q9Y295 (Human)

Gene ID

4733 (DRG1), 13494 (Drg1)

Available reactivities

Bov (Bovine), Chk (Chicken), Hu (Human), Ms (Mouse), Rb (Rabbit), Rt (Rat), Ze (Zebrafish), African clawed frog, Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Ye (Yeast)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of DRG1 / NEDD3 antibody

DRG1 (developmentally regulated GTP binding protein 1), also known as NEDD3 (neural precursor cell expressed developmentally down-regulated protein 3), is a 367 amino acid protein that localizes to the cytoplasm and belongs to the GTP1/OBG family. Expressed at high levels in heart, kidney and skeletal muscle and at lower levels in brain, liver, placenta, lung, colon and spleen, DRG1 binds to TAL1 and TAL2 and is thought to play a role in cell proliferation and differentiation, as well as in apoptosis, suggesting a role in tumor formation and metastasis. DRG1 is subject to polyubiquitination and sumoylation, the former of which induces proteolytic degradation. The gene encoding DRG1 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.

General readings

de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)
Bandyopadhyay, S., et al. Cancer Res. 66(24):11983-11990(2006)
Bandyopadhyay, S., et al. Oncogene 23(33):5675-5681(2004)
Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004)
Bandyopadhyay, S., et al. Cancer Res. 63(8):1731-1736(2003)

19 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DRG1 / NEDD3 antibody

  Rabbit Polyclonal Anti-DRG1 Antibody  
WB Suggested Anti-DRG1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human Spleen Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ye, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

DRG1 / NEDD3 antibody

  Rabbit Polyclonal Anti-DRG1 Antibody  
WB Suggested Anti-DRG1 Antibody Titration: 0.2-1 ug/ml; Positive Control: 721_B cell lysate.DRG1 is supported by BioGPS gene expression data to be expressed in 721_B Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

DRG1 / NEDD3 antibody

  Rabbit Polyclonal Anti-DRG1 Antibody  
Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-4: Human fetal liver tissue, Human brain tissue, 293T cells, Hela cells, Primary antibody: (DRG1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DRG1 / NEDD3 (C-term) antibody

Formalin fixed and paraffin embedded human cerebellum tissue reacted with DRG1 / NEDD3 Antibody (C-term) Cat.-No AP51320PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DRG1 / NEDD3 antibody

Human Spleen; WB Suggested Anti-DRG1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human Spleen; DRG1 antibody - N-terminal region (ARP48239_P050) in Human Spleen cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Hu, Ms, Rb, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

DRG1 / NEDD3 antibody

Human 721_B; WB Suggested Anti-DRG1 Antibody Titration: 0.2-1 ug/ml. Positive Control: 721_B cell lysate. DRG1 is supported by BioGPS gene expression data to be expressed in 721_B.; DRG1 antibody - middle region (ARP48240_P050) in Human 721_B cells using Western Blot Rabbit Aff - Purified Bov, Chk, Hu, Ms, Rb, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

CRISPR

Catalog No. Species Donor Vector  

Drg1 - mouse gene knockout kit via CRISPR

Drg1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Drg1 - mouse gene knockout kit via CRISPR

Drg1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Drg1 - mouse gene knockout kit via CRISPR

Drg1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Drg1 - mouse gene knockout kit via CRISPR

Drg1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DRG1 / NEDD3

  Recombinant protein of human developmentally regulated GTP binding protein 1 (DRG1)  
DRG1 / NEDD3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

DRG1 / NEDD3 (1-367, His-tag)

DRG1 / NEDD3 Human Purified > 85 % E. coli
0.25 mg / €1,000.00
  Acris Antibodies GmbH

DRG1 / NEDD3 (1-367, His-tag)

DRG1 / NEDD3 Human Purified > 85 % E. coli
50 µg / €370.00
  Acris Antibodies GmbH

DRG1 / NEDD3

DRG1 / NEDD3 Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

DRG1 overexpression lysate

DRG1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, DRG1 (mGFP-tagged) - Human developmentally regulated GTP binding protein 1 (DRG1), 200 uL, >10^7 TU/mL

Lenti ORF particles, DRG1 (mGFP-tagged) - Human developmentally regulated GTP binding protein 1 (DRG1), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, DRG1 (Myc-DDK tagged) - Human developmentally regulated GTP binding protein 1 (DRG1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, DRG1 (Myc-DDK tagged) - Human developmentally regulated GTP binding protein 1 (DRG1) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Drg1 (GFP-tagged) - Mouse developmentally regulated GTP binding protein 1 (Drg1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Drg1 (GFP-tagged) - Mouse developmentally regulated GTP binding protein 1 (Drg1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Drg1 (Myc-DDK-tagged) - Mouse developmentally regulated GTP binding protein 1 (Drg1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Drg1 (Myc-DDK-tagged) - Mouse developmentally regulated GTP binding protein 1 (Drg1), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

19 Item(s)

per page
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