DTX3L / BBAP antibody

Principal name

DTX3L / BBAP antibody

Alternative names for DTX3L / BBAP antibody

Protein deltex-3-like, Rhysin-2, B-lymphoma- and BAL-associated protein

SwissProt ID

Q8TDB6 (Human)

Gene ID

151636 (DTX3L)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP)

Background of DTX3L / BBAP antibody

Ubiquitin ligase that mediates monoubiquitination of 'Lys-91' of histone H4 (H4K91ub1), in response to DNA damage. Protects cells exposed to DNA-damaging agents. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 'Lys-20' methylation (H4K20me). Involved in the recruitment of 53BP1/TP53BP1 to sites of DNA damage by mediating H4K91ub1 formation. In concert with PARP9, plays a role in PARP1-dependent DNA damage repair. PARP1-dependent PARP9-DTX3L-mediated ubiquitination promotes the rapid and specific recruitment of 53BP1/TP53BP1, UIMC1/RAP80, and BRCA1 to DNA damage sites.

General readings

Yan, Q., et al. Mol. Cell 36(1):110-120(2009).
Wilting, S.M., et al. Genes Chromosomes Cancer 47(10):890-905 (2008).
Juszczynski, P., et al. Mol. Cell. Biol. 26(14):5348-5359 (2006).
Takeyama, K., et al. J. Biol. Chem. 278(24):21930-21937 (2003).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DTX3L / BBAP (Center) antibody

Western blot analysis of DTX3L / BBAP Antibody Cat.-No AP51334PU-N in SK-BR-3 cell line lysates (35ug/lane). This demonstrates the DTX3L antibody detected the DTX3L protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DTX3L / BBAP antibody

DTX3L polyclonal antibody (A01), Lot # ABNOVA060707QCS1 Western Blot analysis of DTX3L expression in A-431 ( Cat # L015V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

DTX3L / BBAP antibody

Immunoperoxidase of monoclonal antibody to DTX3L on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 6 ug/ml] Mouse IgG2a 1D10 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

DTX3L / BBAP antibody

Western Blot: DTX3L Antibody [NB100-2872] - Detection of Human DTX3L/BBAP by Western Blot of  Immunoprecipitates. Samples:  Whole cell lysate (1 mg for IP,  20% of IP loaded) from HeLa cells. Antibodies: Affinity purified  rabbit anti-DTX3L/BBAP antibody NB100-2872 used for IP at 3 mcg/mg lysate. DTX3L/BBAP was  also immunoprecipitated by another rabbit anti-DTX3L/BBAP antibody  and NB100-2873, which recognize  downstream epitopes.  Detection:  Chemiluminescence with an exposure  time of 3 minutes. Rabbit Aff - Purified Hu IP
0.1 mg / €440.00
  Novus Biologicals Inc.

DTX3L / BBAP antibody

WB and Immunoprecipitation: DTX3L Antibody [NB100-2873] - Detection of Human and Mouse DTX3L/BBAP on HeLa whole cell lystate using NB100-2873. DTX3L/BBAP was also immunoprecipitated by another rabbit anti-DTX3L/BBAP antibody and NB100-2872. Rabbit Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

DTX3L / BBAP antibody

Immunohistochemistry-Paraffin: DTX3L Antibody [NBP1-88699] - Immunohistochemical staining of human lung shows strong cytoplasmic and membranous positivity in alveolar cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DTX3L / BBAP

DTX3L / BBAP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

DTX3L / BBAP

DTX3L / BBAP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

DTX3L / BBAP

DTX3L / BBAP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

9 Item(s)

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