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DTX3L / BBAP antibody

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Principal name

DTX3L / BBAP antibody

Alternative names for DTX3L / BBAP antibody

Protein deltex-3-like, Rhysin-2, B-lymphoma- and BAL-associated protein

SwissProt ID

Q8TDB6 (Human)

Gene ID

151636 (DTX3L)

Ncbi ID

9606, NP_612144.1, NP_612144

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP)

Background of DTX3L / BBAP antibody

Ubiquitin ligase that mediates monoubiquitination of 'Lys-91' of histone H4 (H4K91ub1), in response to DNA damage. Protects cells exposed to DNA-damaging agents. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 'Lys-20' methylation (H4K20me). Involved in the recruitment of 53BP1/TP53BP1 to sites of DNA damage by mediating H4K91ub1 formation. In concert with PARP9, plays a role in PARP1-dependent DNA damage repair. PARP1-dependent PARP9-DTX3L-mediated ubiquitination promotes the rapid and specific recruitment of 53BP1/TP53BP1, UIMC1/RAP80, and BRCA1 to DNA damage sites.

General readings

Yan, Q., et al. Mol. Cell 36(1):110-120(2009).
Wilting, S.M., et al. Genes Chromosomes Cancer 47(10):890-905 (2008).
Juszczynski, P., et al. Mol. Cell. Biol. 26(14):5348-5359 (2006).
Takeyama, K., et al. J. Biol. Chem. 278(24):21930-21937 (2003).

H00151636-M01 - DTX3L / BBAP
Immunoperoxidase of monoclonal antibody to DTX3L on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 6 ug/ml]
H00151636-M01 - DTX3L / BBAP
DTX3L monoclonal antibody (M01), clone 1D10 Western Blot analysis of DTX3L expression in A-431 ( Cat # L015V1 ).
H00151636-M01 - DTX3L / BBAP
Detection limit for recombinant GST tagged DTX3L is approximately 0.3ng/ml as a capture antibody.
H00151636-A01 - DTX3L / BBAP
DTX3L polyclonal antibody (A01), Lot # ABNOVA060707QCS1 Western Blot analysis of DTX3L expression in A-431 ( Cat # L015V1 ).
11963-1-AP - DTX3L / BBAP
Human lung tissue were subjected to SDS PAGE followed by western blot with 11963-1-AP(DTX3L antibody) at dilution of 1:500
NB100-2872 - DTX3L / BBAP
Western Blot: DTX3L Antibody [NB100-2872] - Detection of Human DTX3L/BBAP by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-DTX3L/BBAP antibody NB100-2872 used for IP at 3 mcg/mg lysate. DTX3L/BBAP was also immunoprecipitated by another rabbit anti-DTX3L/BBAP antibody and NB100-2873, which recognize downstream epitopes. Detection: Chemiluminescence with an exposure time of 3 minutes.
NB100-2873 - DTX3L / BBAP
WB and Immunoprecipitation: DTX3L Antibody [NB100-2873] - Detection of Human and Mouse DTX3L/BBAP on HeLa whole cell lystate using NB100-2873. DTX3L/BBAP was also immunoprecipitated by another rabbit anti-DTX3L/BBAP antibody and NB100-2872.
NBL1-10038 - DTX3L Lysate
Western Blot: DTX3L Lysate [NBL1-10038] - Western Blot experiments. Left-Control; Right -Over-expression Lysate for DTX3L
GTX116369 - DTX3L / BBAP
Sample (30 ug of whole cell lysate) A: A431 7.5% SDS PAGE GTX116369 diluted at 1:1000
AP51334PU-N - DTX3L / BBAP
Western blot analysis of DTX3L / BBAP Antibody Cat.-No AP51334PU-N in SK-BR-3 cell line lysates (35ug/lane). This demonstrates the DTX3L antibody detected the DTX3L protein (arrow).
NBP1-88699 - DTX3L / BBAP
Immunohistochemistry-Paraffin: DTX3L Antibody [NBP1-88699] - Immunohistochemical staining of human lung shows strong cytoplasmic and membranous positivity in alveolar cells.
NBP1-88699 - DTX3L / BBAP
Western Blot: DTX3L Antibody [NBP1-88699] Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10 | Lane 2: Negative control (vector only transfected HEK293T lysate) | Lane 3: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells.

9 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DTX3L / BBAP (Center) antibody
Western blot analysis of DTX3L / BBAP Antibody Cat.-No AP51334PU-N in SK-BR-3 cell line lysates (35ug/lane). This demonstrates the DTX3L antibody detected the DTX3L protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DTX3L / BBAP antibody
DTX3L polyclonal antibody (A01), Lot # ABNOVA060707QCS1 Western Blot analysis of DTX3L expression in A-431 ( Cat # L015V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

DTX3L / BBAP antibody
Immunoperoxidase of monoclonal antibody to DTX3L on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 6 ug/ml] Mouse IgG2a 1D10 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.
+2 additional images

DTX3L / BBAP antibody
Western Blot: DTX3L Antibody [NB100-2872] - Detection of Human DTX3L/BBAP by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-DTX3L/BBAP antibody NB100-2872 used for IP at 3 mcg/mg lysate. DTX3L/BBAP was also immunoprecipitated by another rabbit anti-DTX3L/BBAP antibody and NB100-2873, which recognize downstream epitopes. Detection: Chemiluminescence with an exposure time of 3 minutes. Rabbit Aff - Purified Hu IP
0.1 mg / €440.00
  Novus Biologicals Inc.

DTX3L / BBAP antibody
WB and Immunoprecipitation: DTX3L Antibody [NB100-2873] - Detection of Human and Mouse DTX3L/BBAP on HeLa whole cell lystate using NB100-2873. DTX3L/BBAP was also immunoprecipitated by another rabbit anti-DTX3L/BBAP antibody and NB100-2872. Rabbit Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

DTX3L / BBAP antibody
Immunohistochemistry-Paraffin: DTX3L Antibody [NBP1-88699] - Immunohistochemical staining of human lung shows strong cytoplasmic and membranous positivity in alveolar cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.
+1 additional image

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DTX3L / BBAP
DTX3L / BBAP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

DTX3L / BBAP
DTX3L / BBAP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

DTX3L / BBAP
DTX3L / BBAP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

9 Item(s)

per page

Available Filters

Product Type
  1. Primary Antibody (6)
  2. Protein | Growth Factor (3)
Clonality
  1. Polyclonal (5)
  2. Monoclonal (1)
Target
  1. DTX3L / BBAP (9)
Property
  1. Center (1)
Reactivity
  1. Human (Hu) (6)
Applications
  1. Western blot / Immunoblot (WB) (5)
  2. Enzyme Immunoassay (E) (2)
  3. Immunoprecipitation (IP) (2)
  4. Paraffin Sections (P) (2)
Presentation
  1. Aff - Purified (4)
  2. Purified (1)
  3. Serum (1)
Host
  1. Rabbit (4)
  2. Mouse (2)
Images
  1. 1 image (7)
  2. 3+ images (1)
Images: Applications
  1. Western blot / Immunoblot (WB) (6)
  2. Paraffin Sections (P) (2)
  3. ELISA (capture) (E(capture)) (1)
Species (Protein)
  1. Human (3)
Source
  1. in vitro transl. (2)
  2. HEK293 cells (1)
Manufacturer
  1. Abnova Taiwan Corp. (4)
  2. Novus Biologicals Inc. (3)
  3. Acris - OriGene (2)
Service
  • OriGene EU
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