DUSP12 antibody

Principal name

DUSP12 antibody

Alternative names for DUSP12 antibody

YVH1, Dual specificity protein phosphatase 12, Dual specificity tyrosine phosphatase YVH1

SwissProt ID

Q9D0T2 (Mouse), Q9JIM4 (Rat), Q9UNI6 (Human)

Gene ID

11266 (DUSP12), 1126603 (Q9PEG5)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Dot blot (Dot), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of DUSP12 antibody

DUSP12 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP12 is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.

General readings

Hasstedt,S.J., Ann. Hum. Genet. 72 (PT 2), 163-169 (2008)

19 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DUSP12 antibody

Gel: 10%SDS-PAGE, Lysate: 40 µg, Lane: Jurkat cells, Primary antibody: DUSP12 Antibody at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DUSP12 antibody

Predicted cell location: Cytoplasm. Positive control: Human thyroid cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DUSP12 antibody at dilution 1/77, on the right is treated with the fusion protein. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

DUSP12 antibody

WB Suggested Anti-DUSP12 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Human heart Rabbit IgG Purified Bov, Can, Eq, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

DUSP12 antibody

DUSP12 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

DUSP12 antibody

Western Blot analysis of DUSP12 expression in transfected 293T cell line (H00011266-T01) by DUSP12 MaxPab polyclonal antibody.

Lane 1: DUSP12 transfected lysate(37.4 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

DUSP12 antibody

Immunoprecipitation of DUSP12 transfected lysate using anti-DUSP12 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with DUSP12 MaxPab mouse polyclonal antibody (B01) (H00011266-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

DUSP12 antibody

Western Blot analysis of DUSP12 expression in transfected 293T cell line (H00011266-T01) by DUSP12 MaxPab polyclonal antibody.

Lane 1: DUSP12 transfected lysate(37.70 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

DUSP12 antibody

Immunoblot analysis of cell lysates.
Lane 1 : Bosc23 cell lysate.
Lane 2 : Bosc23 cell lysate transfected with Myc/His/Tau ( 1-441 a. a. ).
Lane 3 : Bosc23 cell lysate transfected with Myc/His/DUSP12 ( 21-340 a. a. ).
Lane 4 : Bosc23 cell lysate transfected with GFP-Ubiquitin+1. Mouse AF28B2 Hu E, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

DUSP12 antibody

Human Heart; WB Suggested Anti-DUSP12 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human heart; DUSP12 antibody - N-terminal region (ARP32856_P050) in Human Heart cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

DUSP12 antibody

Western Blot: DUSP12 Antibody [NBP1-31197] - Western blot analysis of DUSP12 Antibody on: A: H1299 10% SDS PAGE diluted at 1:500 Rabbit IgG Hu Dot, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

DUSP12 antibody

Immunohistochemistry-Paraffin: DUSP12 Antibody [NBP1-84961] - Immunohistochemical staining of human colon shows strong luminal membranous and cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DUSP12

DUSP12 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

DUSP12

DUSP12 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

DUSP12

DUSP12 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

DUSP12

DUSP12 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

DUSP12

DUSP12 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

DUSP12 (Human) Matched Antibody Pair

DUSP12 (Human) Matched Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

DUSP12 293T Cell Transient Overexpression Lysate(Denatured)

DUSP12 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

DUSP12 overexpression lysate

DUSP12 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

19 Item(s)

per page
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