DUSP2 / PAC1 antibody

Principal name

DUSP2 / PAC1 antibody

Alternative names for DUSP2 / PAC1 antibody

PAC-1, Dual specificity protein phosphatase 2, Dual specificity protein phosphatase PAC-1

SwissProt ID

O74731 (Schpo), P53720 (Yeast), Q05922 (Mouse), Q05923 (Human)

Gene ID

1844 (DUSP2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of DUSP2 / PAC1 antibody

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus. [provided by RefSeq]

General readings

Caunt,C.J., et.al., J. Biol. Chem. 283 (10), 6241-6252 (2008).
Baranyai,R., et.al., Neuropsychobiology 57 (3), 146-150 (2008).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DUSP2 / PAC1 (C-term) antibody

Western blot analysis of DUSP2 / PAC1 Antibody (C-term) Cat.-No AP51339PU-N in mouse liver tissue lysates (35ug/lane). DUSP2 (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu, Ms F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DUSP2 / PAC1 antibody

DUSP2 / PAC1 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

DUSP2 / PAC1 antibody

Immunohistochemistry: PAC1 Antibody [NB100-74485] - Immunohistochemical staining of PAC1 in human myenteric ganglia cells of the small intestine using NB100-74485 Rabbit Serum Hu ICC/IF, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Lysates (Overexpressed)

Catalog No.    

DUSP2 overexpression lysate

DUSP2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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