DUSP3 antibody

Principal name

DUSP3 antibody

Alternative names for DUSP3 antibody

VHR, Dual specificity protein phosphatase 3, Dual specificity protein phosphatase VHR, Vaccinia H1-related phosphatase

SwissProt ID

P51452 (Human), Q9D7X3 (Mouse)

Gene ID

1845 (DUSP3), 72349 (Dusp3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP)

Background of DUSP3 antibody

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases ictivate their target kises by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kise superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kises, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1. [provided by RefSeq]

General readings

Alonso, A., Rahmouni, S., Williams, S., van Stipdonk, M., Jaroszewski, L., Godzik, A., Abraham, R.
T., Schoenberger, S. P., Mustelin, T. Tyrosine phosphorylation of VHR phosphatase by
ZAP-70. Nature Immun. 4: 44-48, 2003.
2. Ishibashi, T., Bottaro, D. P., Chan, A., Miki, T., Aaronson, S. A. Expression cloning of a human
dual-specificity phosphatase. Proc. Nat. Acad. Sci. 89: 12170-12174, 1992.
3. Patterson, K. I., Brummer, T., O'Brien, P. M., Daly, R. J. Dual-specificity phosphatases: critical
regulators with diverse cellular targets.Biochem. J. 418: 475-489, 2009.

16 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DUSP3 antibody

  Rabbit Polyclonal antibody to DUSP3 (dual specificity phosphatase 3)  
Sample (50 ug of whole cell lysate). A: mouse stomach. 12% SDS PAGE. TA308662 diluted at 1:1000. Rabbit IgG Aff - Purified Hu, Ms P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DUSP3 antibody

The Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human DUSP3 antibody (1:3000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Lane 1.: HeLa cell lysate 
Lane 2.: HepG2 cell lysate 
Lane 3.: Jurkat cell lysate 
Lane 4.: MCF7 cell lysate
Lane 5.: 293T cell lysate
Lane 6.: U87MG cell lysate
Lane 7.: K562 cell lysate Mouse IgG2b AT9E6 Purified Hu E, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

DUSP3 antibody

The Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human DUSP3 antibody (1:3000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Lane 1.: HeLa cell lysate 
Lane 2.: HepG2 cell lysate 
Lane 3.: Jurkat cell lysate 
Lane 4.: MCF7 cell lysate
Lane 5.: 293T cell lysate
Lane 6.: U87MG cell lysate
Lane 7.: K562 cell lysate Mouse IgG2b AT9E6 Purified Hu E, WB
50 µl / €220.00
  Acris Antibodies GmbH

DUSP3 (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

DUSP3 - human gene knockout kit via CRISPR

DUSP3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Dusp3 - mouse gene knockout kit via CRISPR

Dusp3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Dusp3 - mouse gene knockout kit via CRISPR

Dusp3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dusp3 - mouse gene knockout kit via CRISPR

Dusp3 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dusp3 - mouse gene knockout kit via CRISPR

Dusp3 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

DUSP3

  Recombinant protein of human dual specificity phosphatase 3 (DUSP3)  
DUSP3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

DUSP3 (1-185, His-tag)

DUSP3 Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

DUSP3 (1-185, His-tag)

DUSP3 Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, DUSP3 (mGFP-tagged) - Human dual specificity phosphatase 3 (DUSP3), 200 uL, >10^7 TU/mL

Lenti ORF particles, DUSP3 (mGFP-tagged) - Human dual specificity phosphatase 3 (DUSP3), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, DUSP3 (Myc-DDK tagged) - Human dual specificity phosphatase 3 (DUSP3) , 200 uL, >10^7 TU/mL

Lenti ORF particles, DUSP3 (Myc-DDK tagged) - Human dual specificity phosphatase 3 (DUSP3) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Dusp3 (GFP-tagged) - Mouse dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) (Dusp3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Dusp3 (GFP-tagged) - Mouse dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) (Dusp3), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Dusp3 (Myc-DDK-tagged) - Mouse dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) (Dusp3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Dusp3 (Myc-DDK-tagged) - Mouse dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) (Dusp3), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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