DUSP9 / MKP4 antibody
Principal name
DUSP9 / MKP4 antibody
Alternative names for DUSP9 / MKP4 antibody
MAP kinase phosphatase 4, Dual specificity protein phosphatase 9, Mitogen-activated protein kinase phosphatase 4
SwissProt ID
Q99956 (Human)
Gene ID
1852 (DUSP9)
Ncbi ID
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)
Background of DUSP9 / MKP4 antibody
Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X and MKP-4. Human MKP-1 maps to chromosome 5q34 and encodes a 367 amino acid, 39 kDa protein that dephosphorylates MAP kinase ERK2 on both Thr-183 and Tyr-185.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AP20456PU-N | DUSP9 / MKP4 antibody |
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 |
Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, P, WB |
0.1 mg /
€370.00
|
||
| OriGene Technologies GmbH | |||||||
 +1 additional image |
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| AP32268PU-N | DUSP9 / MKP4 antibody |
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 |
Rabbit | IgG | Aff - Purified | Hu, Ms, Rt | E, ICC/IF, P, WB |
50 µl /
€425.00
|
|
| OriGene Technologies GmbH | |||||||
| +2 additional images |
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Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP309271 | DUSP9 / MKP4 |
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| Recombinant protein of human dual specificity phosphatase 9 (DUSP9) | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC209271L2V | Lenti ORF particles, DUSP9 (mGFP-tagged) - Human dual specificity phosphatase 9 (DUSP9), 200 uL, >10^7 TU/mL |
|
 |
200 µl /
€1,110.00
|
|
| OriGene Technologies, Inc. | ||
| RC209271L1V | Lenti ORF particles, DUSP9 (Myc-DDK tagged) - Human dual specificity phosphatase 9 (DUSP9) , 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,000.00
|
|
| OriGene Technologies, Inc. | ||
