DUX4 / DUX10 antibody

Principal name

DUX4 / DUX10 antibody

Alternative names for DUX4 / DUX10 antibody

Double homeobox protein 4, Double homeobox protein 10, Double homeobox protein 4/10

SwissProt ID

Q9UBX2 (Human)

Gene ID

22947 (DUX4), 100288687 (DUX4L)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine)

Available hosts

Mouse, Rabbit

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of DUX4 / DUX10 antibody

DUX4 (also known as Double homeobox 4) is the leading candidate causative gene for facioscapulohumeral dystrophy (FSHD), a degenerative skeletal muscle disease and one of the most common muscular dystrophies. FSHD is caused by the deletion of a subset of D4Z4 macrosatellite repeats on chromosome 4. Each repeat contains a retrogene encoding the double-homeobox factor DUX4. DUX4 expression is epigenetically suppressed in differentiated tissues and the residual DUX4 transcripts are spliced to remove the carboxyterminal domain that has been associated with cell toxicity. In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle, and possibly other differentiated tissues, and results in a small percentage of cells expressing relatively abundant amounts of the full-length DUX4 mRNA and protein. [Snider et al. (2010) PLoS Genetics.6(10): e1001181]

General readings

Dixit M, Ansseau E, Tassin A, Winokur S, Shi R, Qian H, Sauvage S, Matt

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

DUX4 / DUX10 antibody

Western blot using anti-DUX4 N-terminus mouse monoclonal on C2C12 cells transfected with pCS2+DUX4, which contains an additional upstream start site. Mouse IgG1 P2B1 Purified Hu ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

DUX4 / DUX10 antibody

Host: Rabbit; Target Name: DUX4; Sample Tissue: HCT15 Whole Cell lysates; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Can, Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

DUX4 / DUX10 antibody

Western Blot: DUX4 Antibody (P4H2) [TA336793] - Analysis of DUX4 expression in 1) human testis and 2) DUX4 protein lysates. Mouse IgG1 P4H2 Purified Hu C, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

DUX4 / DUX10 antibody

Host: Rabbit; Target Name: DUX4; Sample Tissue: THP-1 Whole cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

DUX4 / DUX10 (Center) antibody

Western blot analysis of DUX4 / DUX10 Antibody Cat.- AP51342PU-N in HL-60 cell line lysates (35ug/lane). This demonstrates the DUX4 antibody detected the DUX4 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DUX4 / DUX10 (C-term) antibody

Western blot analysis of DUX4 / DUX10 Antibody (C-term) Cat.-No AP51343PU-N in A549 cell line lysates (35ug/lane). This demonstrates the DUX4 antibody detected the DUX4 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

DUX4 / DUX10 antibody

DUX4 / DUX10 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

DUX4 / DUX10 antibody

DUX4 / DUX10 Mouse IgG1 P4H2 Purified Hu C, ICC/IF, P, WB
25 µl / €170.00
  Novus Biologicals Inc.

8 Item(s)

per page
  • LinkedIn