Dynactin subunit 2 antibody

Principal name

Dynactin subunit 2 antibody

Alternative names for Dynactin subunit 2 antibody

DCTN2, DCTN50, Dynactin 2, p50 dynamitin, RBP50, 50 kDa dynein-associated polypeptide, Dynactin complex 50 kDa subunit

SwissProt ID

Q13561 (Human), Q3ZCF0 (Bovin), Q6AYH5 (Rat), Q99KJ8 (Mouse), Q9PTG6 (Chick)

Gene ID

10540 (DCTN2), 69654 (Dctn2), 299850

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), Ze (Zebrafish), African clawed frog, Mky (Monkey), Rb (Rabbit), Eq (Equine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), EPair for Elisa (EPair), Immunoprecipitation (IP)

Background of Dynactin subunit 2 antibody

DCTN2 is a 50-kD subunit of dyctin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dyctin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dyctin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dyctin subunits. It may interact directly with the largest subunit (p150) of dyctin and may affix p150 in place.This gene encodes a 50-kD subunit of dyctin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dyctin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dyctin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dyctin subunits. It may interact directly with the largest subunit (p150) of dyctin and may affix p150 in place. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications.

General readings

Echeverri C.J., et al. (1996) J. Cell Biol. 132:617-633
Gevaert K., et al. (2003) Nat. Biotechnol. 21:566-569

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Dynactin subunit 2 antibody

  Rabbit polyclonal p50 Dynamitin antibody  
Western blot analysis of extracts from A549 cells, using p50 dynamitin antibody (#TA315072).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Dynactin subunit 2 antibody

  Rabbit anti-DCTN2 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using DCTN2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Dynactin subunit 2 antibody

  Rabbit Polyclonal Anti-DCTN2 Antibody - N-terminal region  
WB Suggested Anti-DCTN2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Dynactin subunit 2 antibody

  Rabbit Polyclonal Anti-p50 Dynamitin Antibody  
Western blot analysis on A549 cell lysate using p50 Dynamitin Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Dynactin subunit 2 antibody

Western blot (WB) analysis of p50 Dynamitin antibody (Cat.-No.: AP06265PU-N) in extracts from A549 cells. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Dynactin subunit 2 (Center) antibody

Formalin fixed and paraffin embedded human stomach tissue stained with  Dynactin subunit 2 Antibody Cat.-No AP51207PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Dynactin subunit 2 antibody

Western blot analysis of extracts from A549 cells, using p50 Dynamitin Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

Dynactin subunit 2 antibody

Western blot analysis of extracts from A549 cells, using p50 Dynamitin Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

DCTN2 - human gene knockout kit via CRISPR

DCTN2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

DCTN2 - human gene knockout kit via CRISPR

DCTN2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

DCTN2 - human gene knockout kit via CRISPR

DCTN2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

DCTN2 - human gene knockout kit via CRISPR

DCTN2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dctn2 - mouse gene knockout kit via CRISPR

Dctn2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Dctn2 - mouse gene knockout kit via CRISPR

Dctn2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dctn2 - mouse gene knockout kit via CRISPR

Dctn2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Dctn2 - mouse gene knockout kit via CRISPR

Dctn2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Dynactin subunit 2

  Recombinant protein of human dynactin 2 (p50) (DCTN2)  
Dynactin subunit 2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Dynactin subunit 2 (1-401, His-tag)

Dynactin subunit 2 Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

Dynactin subunit 2 (1-401, His-tag)

Dynactin subunit 2 Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

Dynactin subunit 2 (1-403, His-tag)

Dynactin subunit 2 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

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