Dynactin subunit 3 antibody

Principal name

Dynactin subunit 3 antibody

Alternative names for Dynactin subunit 3 antibody

DCTN3, DCTN22

SwissProt ID

O75935 (Human)

Gene ID

11258 (DCTN3)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Goat

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of Dynactin subunit 3 antibody

This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants. Transcript Variant: This variant contains an additional 97 nt within the 3' coding region, as compared to variant 1 resulting in a frame-shift. Isoform 2 encoded by this variant has a different, and 10 aa shorter C-terminus than isoform 1.

General readings

1. Abba MC, Sun H, Hawkins KA, Drake JA, Hu Y, Nunez MI, Gaddis S, Shi T, Horvath S, Sahin A, Aldaz CM. Breast cancer molecular signatures as determined by SAGE: correlation with lymph node status. Mol Cancer Res. 2007 Sep;5(9):881-90.
PMID: 17855657

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Dynactin subunit 3 antibody

  Goat Anti-DCTN3 Antibody  
(0.03ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

DCTN3 - human gene knockout kit via CRISPR

DCTN3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

DCTN3 - human gene knockout kit via CRISPR

DCTN3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

DCTN3 - human gene knockout kit via CRISPR

DCTN3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

DCTN3 - human gene knockout kit via CRISPR

DCTN3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Dynactin subunit 3 (transcript variant 1)

  Recombinant protein of human dynactin 3 (p22) (DCTN3), transcript variant 1  
Dynactin subunit 3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

DCTN3 overexpression lysate

DCTN3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

DCTN3 overexpression lysate

DCTN3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, DCTN3 (mGFP-tagged) - Human dynactin 3 (p22) (DCTN3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, DCTN3 (mGFP-tagged) - Human dynactin 3 (p22) (DCTN3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, DCTN3 (Myc-DDK tagged) - Human dynactin 3 (p22) (DCTN3), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, DCTN3 (Myc-DDK tagged) - Human dynactin 3 (p22) (DCTN3), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

10 Item(s)

per page
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