Dystrophin / DMD antibody

Principal name

Dystrophin / DMD antibody

SwissProt ID

O97592 (Canfa), P11530 (Rat), P11531 (Mouse), P11532 (Human), P11533 (Chick), Q5GN48 (Pig)

Gene ID

1756 (DMD)

Available reactivities

Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Fi (Fish)

Available hosts

Mouse, Rabbit

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Enzyme Immunoassay (E), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoelectron Microscopy (EM)

Background of Dystrophin / DMD antibody

Dystrophin(DMD) gene has 79 exons spanning at least 2,300 kb (2.3 Mb). The C terminus of the dystrophin protein is encoded by a highly conserved, alternatively spliced region of the gene. beta-dystroglycan binding activity is expressed by the dystrophin fragment spanning amino acids 3026-3345 containing the ZZ domain. DMD transcript is formed by at least 60 exons; the first half of the transcript is formed by a minimum of 33 exons spanning nearly 1000 kb, and the remaining portion has at least 27 exons that may spread over a similar distance. Dystrophin gene is expressed at a higher level in primary cultures of neuronal cells than in astro-glial cells derived from adult mouse brain.over expression of dystrophin prevents the development of the abnormal mechanical properties associated with dystrophic muscle without causing deleterious side effects.

General readings

1 Chelly, J.; Hamard, G.; Koulakoff, A.; Kaplan, J.-C.; Kahn, A.; Berwald-Netter, Y. : Dystrophin gene transcribed from different promoters in neuronal and glial cells. Nature 344: 64-65, 1990.
2 Cox, G. A.; Cole, N. M.; Matsumura, K.; Phelps, S. F.; Hauschka, S. D.; Campbell, K. P.; Faulkner, J. A.; Chamberlain, J. S. : Overexpression of dystrophin in transgenic mdx mice eliminates dystrophic symptoms without toxicity. Nature 364: 725-729, 1993.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Dystrophin / DMD antibody

AP15529PU Dystrophin antibody staining of Human Skeletal Muscle. Rabbit Purified Hu, Rt P, WB
0.5 ml / €360.00
  Acris Antibodies GmbH

Dystrophin / DMD antibody

AP15529PU Dystrophin antibody staining of Human Skeletal Muscle. Rabbit Purified Hu, Rt P, WB
1 ml / €450.00
  Acris Antibodies GmbH

Dystrophin / DMD antibody

AP15529PU Dystrophin antibody staining of Human Skeletal Muscle. Rabbit Purified Hu, Rt P, WB
0.1 ml / €180.00
  Acris Antibodies GmbH

Dystrophin / DMD antibody

Western blot analysis of Dystrophin expression in 3T3 cell lysate (Lane 1) and rat kidney tissue lysate (Lane 2). Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Dystrophin / DMD antibody

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using (DMD Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Dystrophin / DMD antibody

Dystrophin / DMD Rabbit IgG Purified Hu, Ms P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Dystrophin / DMD antibody

Dystrophin / DMD Mouse IgG2b DYS-48 Purified Chk, Hu, Ms, Rt P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Dystrophin / DMD antibody

Western Blot analysis of DMD expression in transfected 293T cell line (H00001756-T01) by DMD MaxPab polyclonal antibody.

Lane 1: DMD transfected lysate(72.20 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Dystrophin / DMD antibody

Dystrophin / DMD Mouse IgG1 3A11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Dystrophin / DMD antibody

Dystrophin / DMD Mouse IgG2b DYS-48 Chk, Hu, Ms, Rt C, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Dystrophin / DMD antibody

Dystrophin / DMD Mouse IgG1 1808 Chk, Fi, Hu, Ms, Rt EM, ICC/IF, P
0.1 mg / €730.00
  Abnova Taiwan Corp.

Dystrophin / DMD antibody

Western blot analysis of DMD expression in NIH/3T3 cell lysate ( Lane 1 ) and rat kidney tissue lysate ( Lane 2 ) . Rabbit Hu, Ms, Rt WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Dystrophin / DMD antibody

Dystrophin / DMD Rabbit Hu, Ms P, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

Dystrophin / DMD antibody

Dystrophin / DMD Mouse IgG2b DYS-48 Ascites Chk, Hu, Ms, Rt C, WB
0.1 mg / €290.00
  Boster Immunoleader

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Dystrophin / DMD (transcript variant Dp140b)

Dystrophin / DMD Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Dystrophin / DMD (transcript variant Dp71ab)

Dystrophin / DMD Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Dystrophin / DMD

Dystrophin / DMD Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Dystrophin / DMD

Dystrophin / DMD Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

DMD (Human) IP-WB Antibody Pair

DMD (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

DMD overexpression lysate

DMD overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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