EBI3 / IL27B antibody

Principal name

EBI3 / IL27B antibody

Alternative names for EBI3 / IL27B antibody

IL-27 subunit beta, IL-27B, Interleukin-27 subunit beta, Epstein-Barr virus-induced gene 3 protein, EBV-induced gene 3 protein

SwissProt ID

O35228 (Mouse), Q14213 (Human)

Gene ID

50498 (Ebi3), 10148 (EBI3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rat, Rabbit, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of EBI3 / IL27B antibody

EBI3 (Epstein-Barr virus Induced-3) is a secreted glycoprotein of the hematopoietin receptor family. It plays a critical regulatory role in the induction of Th2-type immune responses and the development of Th2-mediated tissue inflammation in vivo, which may be mediated through the control of iNKT cell function. EBI3 dimerizes with p28 and p35 subunits of IL-12 to form new proteins IL-27 and IL-35, respectively (Honglian Tong et al, 2010). IL-27 is an early product of activated antigen presenting cell that is produced upon TLR ligation. It negatively regulates Th17 cell differentiation. EBI3 is widely expressed and its expression in dendritic cell is transcriptiolly regulated by TLR sigling via MyD88 and NF-kappaB during inte immune responses preceding cytokine driven Th cell development. EBI3 sigl inhibits delayed-type hypersensitivity responses by suppressing IL-17 production and inducing IL-10 hyperproduction. EBI3 may play a novel role in controlling tumor metastasis via lung CD8+ T cells, and its deficiency is associated with a diminished production of Th2 cytokines which are known to regulate allergic airway inflammation in asthma. Targeted deletion of EBI3 protects mice from lung metastasis (Kerstin A et al, 2008).

Items 1 to 20 of 34 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EBI3 / IL27B (C-term) antibody

  Rabbit Polyclonal EBI3 Antibody  
Western blot analysis of EBI3 in K562 lysate with EBI3 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EBI3 / IL27B antibody

  Rabbit Polyclonal EBI3 Antibody  
Western blot analysis of EBI3 in rat spleen tissue lysate with EBI3 antibody at 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EBI3 / IL27B antibody

  Rat Anti-Mouse EBI3 (IL-27 subunit) Purified (25 ug)  
Mouse IL-27 Recombinant Protein (lane 1) and mouse bone marrow-derived dendritic cells stimulated with LPS (lane 2) or left untreated (lane 3) were analyzed by SDS-PAGE followed by immunoblotting with 5 ug/ml of Anti-Mouse EBI3 (IL-27 subunit) Purified.  Bands were visualized with Anti-Rat IgG HRP . Rat DNT27 Purified Ms WB
25 µg / €120.00
  OriGene Technologies, Inc.

EBI3 / IL27B antibody

  Rabbit Polyclonal IL-27/IL-35 EBI3 Subunit Antibody  
Western Blot: EBI3 Antibody [TA336876] - Analysis of EBI3 using TA336876 in 1) Daudi cell lysate using 2.0 ug/ml, 2) Ramos cell lysate at 2.0 ug/ml in the absence of immunizing peptide 3) Ramos cell lysate at 2.0 ug/ml in the presence of immunizing peptid Rabbit Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EBI3 / IL27B antibody

  Rat Monoclonal IL-27/IL-35 EBI3 Subunit Antibody (10J706)  
Western Blot: EBI3 Antibody (10J706) [TA336877] - Western blot testing of mouse EBI3 monoclonal antibody at 0.1 ug/ml on recombinant protein. Goat anti-rat Ig HRP secondary antibody  and ECL substrate solution were used for this test. Rat IgG2b 10J706 Purified Ms F, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EBI3 / IL27B antibody

  Rat Monoclonal IL-27/IL-35 EBI3 Subunit Antibody (10J763)  
Western Blot: EBI3 Antibody (10J763) [TA336878] - Western blot analysis of mouse thymus tissue using EBI3 antibody at a concentration of 1 ug/ml. Rat IgG2a 10J763 Purified Ms F, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EBI3 / IL27B antibody

  Rat Monoclonal IL-27/IL-35 EBI3 Subunit Antibody (10J803)  
Western Blot: EBI3 Antibody (10J803) [TA336879] - Western blot analysis of mouse thymus tissue using EBI3 antibody at a concentration of 1 ug/ml. Rat IgG2a 10J803 Purified Ms F, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EBI3 / IL27B antibody

  Rat Monoclonal IL-27/IL-35 EBI3 Subunit Antibody (10J811)  
Western Blot: EBI3 Antibody (10J811) [TA336880] - Western blot testing of mouse EBI3 monoclonal antibody at A) 0.1 ug/ml on recombinant protein and B) 3 ug/ml on recombinant mouse IL-35 protein Goat anti-rat Ig HRP secondary antibody  and PicoTect ECL sub Rat IgG2a 10J811 Purified Ms F, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EBI3 / IL27B antibody

  Rat Monoclonal IL-27/IL-35 EBI3 Subunit Antibody (5P6G8)  
Western Blot: EBI3 Antibody (5P6G8) [TA336881] - Analysis using EBI3 antibody. Mouse EBI recombinant protein (A) and lysate from mouse kidney (B) probed with EBI3 antibody at 0.5 and 5 ug/ml, respectively. Goat anti-rat Ig HRP secondary antibody and PicoT Rat IgG2b 5P6G8 Purified Ms F, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EBI3 / IL27B antibody

  Rat Monoclonal IL-27/IL-35 EBI3 Subunit Antibody (5P10D3)  
Western Blot: EBI3 Antibody (5P10D3) [TA336882] - Analysis using EBI3 antibody. Mouse EBI recombinant protein (A) and lysate from mouse kidney (B) probed with EBI3 antibody at 0.5 and 5 ug/ml, respectively. Goat anti-rat Ig HRP secondary antibody and Pico Rat IgG2b 5P10D3 Purified Ms F, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EBI3 / IL27B antibody

  Mouse Monoclonal IL-27/IL-35 EBI3 Subunit Antibody (42N1G4)  
Western Blot: EBI3 Antibody (42N1G4) [TA337164] - analysis using EBI3 antibody. Human EBI3 recombinant protein (A) and human IL-35 recombinant protein (B) probed with EBI3 antibody at 5 ug/ml. Goat anti-mouse Ig HRP secondary antibody and PicoTect ECL sub Mouse IgG2b 42N1G4 Purified Hu F, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EBI3 / IL27B antibody

  Mouse Monoclonal IL-27/IL-35 EBI3 Subunit Antibody (42N12F7)  
Western Blot: EBI3 Antibody (42N12F7) [TA337165] - Analysis using EBI3 antibody. Human EBI3 recombinant protein (A) and human IL-35 recombinant protein (B) probed with EBI3 antibody at 5 ug/ml. Goat anti-mouse Ig HRP secondary antibody and PicoTect ECL su Mouse 42N12F7 Purified Hu F, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EBI3 / IL27B antibody

  Mouse Monoclonal IL-27/IL-35 EBI3 Subunit Antibody (15k8D10)  
Western Blot: EBI3 Antibody (15k8D10) [TA337166] - analysis of IL-35-Fc protein (A) and human Fc (B) using EBI3 antibody at 4 ug/ml. Mouse IgG1 15K8D10 Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EBI3 / IL27B antibody

  Rat Monoclonal anti-IL-27/IL-35 EBI3 (monomer, dimer, heterodimer) Antibody  
Western blot analysis of 50 ng of recombinant human IL-27 (lane 1), 50 ng of recombinant mouse IL-27 (lane 2), and 50 ng of recombinant human IL-35 (lane 3) using anti-EBI3 antibody (clone J053B5). Rat IgG2a J053B5 Purified Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EBI3 / IL27B antibody

Human Lyphoid-Dendritic Cells: Formalin-Fixed, Paraffin-Embedded (FFPE). Rat IgG2a DNT27 Aff - Purified Hu, Ms P, WB
50 µg / €470.00
  Acris Antibodies GmbH

EBI3 / IL27B antibody

EBI3 / IL27B Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

EBI3 / IL27B antibody

EBI3 polyclonal antibody (A02), Lot # 051011JC01 Western Blot analysis of EBI3 expression in HepG2 ( Cat # L019V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

EBI3 / IL27B antibody

Detection limit for recombinant GST tagged EBI3 is approximately 0.3ng/ml as a capture antibody. Mouse IgG2a 1D3 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

EBI3 / IL27B antibody

EBI3 / IL27B Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CRISPR

Catalog No. Species Donor Vector  

EBI3 - human gene knockout kit via CRISPR

EBI3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Items 1 to 20 of 34 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn