EDC4 antibody

Principal name

EDC4 antibody

Alternative names for EDC4 antibody

HEDLS, Ge-1, RCD-8, Enhancer of mRNA-decapping protein 4, Human enhancer of decapping large subunit

SwissProt ID

Q3UJB9 (Mouse), Q3ZAV8 (Rat), Q6P2E9 (Human)

Gene ID

23644 (EDC4)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Immunoprecipitation (IP), PLA/Proximity ligation assay (PLA), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of EDC4 antibody

The major eukaryotic mRNA decay pathway occurs through deadenylation, decapping, and 5' to 3' degradation of the mRNA. Decapping is a critical control point in this decay pathway. Edc4 (enhancer of mRNA decapping 4), also known as human enhancer of decapping large subunit (HEDLS), RCD-8 or Ge-1, is a 1,401 amino acid protein belonging to the WD repeat EDC4 family that is involved in mRNA decapping during mRNA degradation. As part of the mRNA degradation process, Edc4 becomes part of a complex that also contains hDcp1a, hDcp2a, RCK and Edc3. Localizing to P-body and cytoplasm, Edc4 contains a nuclear localization sequence (NLS) which enables it to selectively enter the nucleus as well. Edc4 becomes phosphorylated upon DNA damage and exists as two alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 16q22.1.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EDC4 antibody

WB Suggested Anti-EDC4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 12500; Positive Control: Human Liver Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

EDC4 antibody

Western Blot analysis of EDC4 expression in transfected 293T cell line (H00023644-T01) by EDC4 MaxPab polyclonal antibody.

Lane 1: EDC4 transfected lysate(151.70 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

EDC4 antibody

Immunoperoxidase of monoclonal antibody to EDC4 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml] Mouse IgG2a 2E2 Purified Hu E, P
0.1 mg / €370.00
  Abnova Taiwan Corp.

EDC4 antibody

Human Liver; WB Suggested Anti-EDC4 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:12500. Positive Control: Human Liver; EDC4 antibody - N-terminal region (ARP55023_P050) in Human Liver cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

EDC4 antibody

Western Blot and Immunoprecipitation: RCD8 Antibody [NB100-2273] - Detection of Human and Mouse RCD8 on HeLa whole cell lysate using NB100-2273. RCD8 was  also immunoprecipitated by another rabbit anti-RCD8 antibody. Rabbit Aff - Purified Hu, Ms IP, PLA, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

EDC4

EDC4 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

EDC4

EDC4 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

EDC4 293T Cell Transient Overexpression Lysate(Denatured)

EDC4 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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