EDG2 / LPAR1 antibody

Principal name

EDG2 / LPAR1 antibody

Alternative names for EDG2 / LPAR1 antibody

LPAR1, EDG2, LPA1, LPA receptor 1, LPA-1, Lysophosphatidic acid receptor 1, Lysophosphatidic acid receptor Edg-2

SwissProt ID

P46628 (Sheep), P61793 (Mouse), P61794 (Rat), Q28031 (Bovin), Q92633 (Human)

Gene ID

1902 (LPAR1), 116744 (Lpar1), 14745

Available reactivities

Hu (Human), Rt (Rat), Bov (Bovine), Chk (Chicken), Ms (Mouse), Sh (Sheep), Bt (Bat), Can (Canine), Eq (Equine), Fi (Fish), Hst (Hamster), Mky (Monkey), Op (Opossum), Por (Porcine), Prim (Primate), Rb (Rabbit), Xen (Xenopus), Tr (Turkey), Bear

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB), Flow Cytometry (F), Frozen Sections (C)

Background of EDG2 / LPAR1 antibody

The EDG (endothelial differentiation gene) family of G protein-coupled receptors consists of eight family members that bind lysophospholipid (LPL) mediators, including sphingosine-1-phosphate (SPP) and lysophosphatidic acid (LPA). EDG-1, EDG-3, EDG-5 (also designated H218 and AGR16) and EDG-8 bind SPP with high affinity. EDG-6 is a low affinity receptor for SPP. LPA preferentially binds to EDG-2, EDG-4 and EDG-7. The EDG receptors couple to multiple G proteins to signal through Ras, MAP kinase, Rho, Phospholipase C or other tyrosine kinases, which lead to cell survival, growth, migration and differentiation. EDG-1 signals through Gi proteins to activate Akt and is expressed in glioma cells. EDG-2 is expressed in brain, especially in white matter tract regions, while EDG-3 is expressed in cardiovascular tissue and in cerebellum. EDG-4 is highly expressed on leukocytes and brain, and EDG-5 has wide tissue distribution, including cardiovascular tissue and brain. Expressed in lymphoid and hematopoietic tissues and in lung, EDG-6 signals through Gi/o proteins, which activate growth related pathways.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EDG2 / LPAR1 antibody

  LPAR1 (EDG2) mouse monoclonal antibody, clone OTI1G6 (formerly 1G6)  
Anti-LPAR1 mouse monoclonal antibody (TA503737) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LPAR1(RC206065). Mouse IgG2b OTI1G6 Purified Hu F, ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

EDG2 / LPAR1 antibody

  Rabbit Polyclonal EDG2 Antibody  
Detection of EDG2 in A549 whole cell extracts using anti-EDG2. Rabbit Purified Bov, Chk, Hu, Ms, Rt, Sh C, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

EDG2 / LPAR1 antibody

  Rabbit anti-LPAR1 polyclonal antibody  
Western blot analysis of Jurkat cell, SGC-7901 cell and ECL cell lysates with anti-LPAR1 antibody (1:500). Rabbit IgG Purified Bov, Hu, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

EDG2 / LPAR1 antibody

  Rabbit polyclonal anti-EDG2 / LPAR1 antibody  
Western blot analysis of extracts from Jurkat cells, using EDG2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Rt E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

EDG2 / LPAR1 (3rd cytopl. dom.) antibody

  Rabbit Polyclonal Anti-LPAR1 Antibody (Cytoplasmic Domain)  
Anti-EDG2 antibody IHC of human brain, neuron and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Can, Chk, Elephant, Eq, Fi, Hst, Hu, Mky, Ms, Op, Platypus, Por, Prim, Rb, Rt, Sh, Tr, Xen P
50 µg / €379.00
  OriGene Technologies, Inc.

EDG2 / LPAR1 (N-term extracel. dom.) antibody

  Rabbit Polyclonal Anti-LPAR1 Antibody (N-Terminus)  
Anti-EDG2 antibody IHC of human brain, glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Fi, Hst, Hu, Mky, Ms, Op, Por, Prim, Rb, Rt, Sh, Tr P
50 µg / €379.00
  OriGene Technologies, Inc.

EDG2 / LPAR1 antibody

  Rabbit Polyclonal Anti-LPAR1 Antibody  
EDG2 / LPAR1 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

EDG2 / LPAR1 antibody

Immunohistochemistry (IHC) analysis of EDG-2 antibody (Cat.-No.: AP01253PU-N) in paraffin-embedded mouse brain tissue. Rabbit Aff - Purified Hu, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

EDG2 / LPAR1 (N-term) antibody

The anti-EDG2 N-term Antibody is used in Western blot to detect EDG2 in A375 lysate. Rabbit Ig Purified Hu WB

Regular Price: 0.4 ml / €370.00

Special Price: 0.4 ml / €231.00

  Acris Antibodies GmbH

EDG2 / LPAR1 (N-term) antibody

Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE). Rabbit IgG Purified Hu, Rt E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

EDG2 / LPAR1 antibody

EDG2 / LPAR1 Mouse IgG2a 2E2 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

EDG2 / LPAR1 antibody

The LPAR1 polyclonal antibody ( Cat # PAB4719 ) is used in Western blot to detect LPAR1 in A-375 cell lysate. Rabbit Hu E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

EDG2 / LPAR1 antibody

Western blot analysis using LPAR1 polyclonal antibody ( Cat # PAB10126 ) on McA-RH7777 cells transfected with LPAR1 protein at 5 µg/ml. Rabbit Hu WB
0.1 mg / €640.00
  Abnova Taiwan Corp.

EDG2 / LPAR1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using EDG2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Rt E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

EDG2 / LPAR1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using EDG2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Rt E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

Lpar1 - mouse gene knockout kit via CRISPR

Lpar1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Lpar1 - mouse gene knockout kit via CRISPR

Lpar1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lpar1 - mouse gene knockout kit via CRISPR

Lpar1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lpar1 - mouse gene knockout kit via CRISPR

Lpar1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

EDG2 / LPAR1

EDG2 / LPAR1 Human
2 µg / €300.00
  Abnova Taiwan Corp.

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