EDG4 / LPAR2 antibody

Principal name

EDG4 / LPAR2 antibody

Alternative names for EDG4 / LPAR2 antibody

EDG4, LPAR2, Ipa-2, Lysophosphatidic acid receptor 2, Lysophosphatidic acid receptor Edg-4, endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 4

SwissProt ID

Q95KH4 (Macfa), Q9HBW0 (Human), Q9JL06 (Mouse)

Gene ID

9170 (LPAR2)

Available reactivities

Bt (Bat), Bov (Bovine), Can (Canine), Eq (Equine), Hu (Human), Mky (Monkey), Ms (Mouse), Por (Porcine), Prim (Primate), Rb (Rabbit), Rt (Rat), Bear

Available hosts

Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of EDG4 / LPAR2 antibody

The EDG (endothelial differentiation gene) family of G protein coupled receptors consists of eight family members that bind lysophospholipid (LPL) mediators, including sphingosine-1-phosphate (SPP) and lysophosphatidic acid (LPA). EDG-1, EDG-3, EDG-5 (also designated H218 and AGR16) and EDG-8 bind SPP with high-affinity. EDG-6 is a low-affinity receptor for SPP. LPA preferentially binds to EDG-2, EDG-4 and EDG-7. The EDG receptors couple to multiple G proteins to signal through Ras, MAP kinase, Rho, Phospholipase C or other tyrosine kinases, which lead to cell survival, growth, migration and differentiation. EDG-1 signals through Gi proteins to activate Akt and is expressed in glioma cells. EDG-2 is expressed in brain, especially in white matter tract regions, while EDG-3 is expressed in cardiovascular tissue and in cerebellum. EDG-4 is highly expressed on leukocytes and brain, and EDG-5 has wide tissue distribution, including cardiovascular tissue and brain. Expressed in lymphoid and hematopoietic tissues and in lung, EDG-6 signals through Gi/o proteins, which activate growth related pathways.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EDG4 / LPAR2 antibody

Western blot analysis using EDG4/LPA2 (NT) antibody at 5 µg/ml on RH7777 cells transfected with EDG4/LPA2 protein in the absense (1) and presense (2) of blocking peptide. Rabbit IgG Purified Hu WB
0.1 mg / €570.00
  Acris Antibodies GmbH

EDG4 / LPAR2 antibody

Western blot analysis of extracts from COLO205 cells, using EDG4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

EDG4 / LPAR2 antibody

Western blot analysis of extracts from COS-7 cells, using EDG4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

EDG4 / LPAR2 antibody

Predicted cell location: Cytoplasm. Positive control: Human gastric cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human gastric cancer tissue using LPAR2 antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

EDG4 / LPAR2 antibody

Western blot analysis in extracts from COLO205 cells using  EDG-4 / LPAR2 antibody Cat.-No. AP01254PU-N. Rabbit Aff - Purified Hu E, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

EDG4 / LPAR2 antibody

Western blot (WB) analysis of EDG-4 antibody (Cat.-No.: AP01310PU-N) in extracts from COS-7 cells. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

EDG4 / LPAR2 control peptide

EDG4 / LPAR2 Purified
50 µg / €210.00
  Acris Antibodies GmbH

EDG4 / LPAR2 (18-32) antibody

AP07706PU-N EDG4 antibody staining of Formalin-Fixed Paraffin-Embedded Human Prostate at 5-10 µg/ml followed by biotinylated Goat anti-Rabbit IgG secondary antibody, Alkaline Phosphatase-Streptavidin and Chromogen. Rabbit Purified Hu E, P
50 µg / €470.00
  Acris Antibodies GmbH

EDG4 / LPAR2 (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

EDG4 / LPAR2 (3rd Cytopl. Dom) antibody

Cells expressing vector only - immunostained with target antibody Rabbit Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Hu, Mky, Ms, Por, Prim, Rb, Rt ICC/IF, P
50 µg / €470.00
  Acris Antibodies GmbH

EDG4 / LPAR2 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with LPAR2 polyclonal antibody ( Cat # PAB4721 ) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

EDG4 / LPAR2 antibody

Western blot analysis using LPAR2 polyclonal antibody ( Cat # PAB10124 ) at 5 µg/ml on McA-RH7777 cells transfected with LPAR2 protein in the absense (lane 1) and presense (lane 2) of blocking peptide. Hu
0.1 mg / €640.00
  Abnova Taiwan Corp.

EDG4 / LPAR2 antibody

Immunofluorescence analysis of LOVO cells, using EDG4 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

EDG4 / LPAR2 antibody

Immunofluorescence analysis of LOVO cells, using EDG4 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

EDG4 / LPAR2 antibody

Immunofluorescence analysis of MCF7 cells, using EDG4 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

EDG4 / LPAR2 antibody

Immunofluorescence analysis of MCF7 cells, using EDG4 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

EDG4 / LPAR2 antibody

Western Blot: EDG-4 Antibody [NBP1-00791] - Western blot (WB) analysis of EDG-4 (L310) antibody in extracts from COS-7 cells. Rabbit Aff - Purified Hu, Ms WB
0.1 mg / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

EDG4 / LPAR2

EDG4 / LPAR2 Human
2 µg / €450.00
  Abnova Taiwan Corp.

EDG4 / LPAR2

EDG4 / LPAR2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
2 µg / €300.00
  Abnova Taiwan Corp.

EDG4 / LPAR2

EDG4 / LPAR2 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

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