EDG6 / S1P4 antibody

Principal name

EDG6 / S1P4 antibody

Alternative names for EDG6 / S1P4 antibody

EDG-6, Sphingosine 1-phosphate receptor 4, Endothelial differentiation G-protein coupled receptor 6, Sphingosine 1-phosphate receptor Edg-6, S1P receptor Edg-6

SwissProt ID

O95977 (Human), Q9Z0L1 (Mouse)

Gene ID

8698 (S1PR4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Mky (Monkey), Por (Porcine), Gorilla, Hst (Hamster)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Enzyme Immunoassay (E), ELISA (detection) (E(detection))

Background of EDG6 / S1P4 antibody

The EDG (endothelial differentiation gene) family of G protein coupled receptors consists of eight family members that bind lysophospholipid (LPL) mediators, including sphingosine-1-phosphate (SPP) and lysophosphatidic acid (LPA). EDG-1, EDG-3, EDG-5 (also designated H218 and AGR16) and EDG-8 bind SPP with high affinity. EDG-6 is a low affinity receptor for SPP. LPA preferentially binds to EDG-2, EDG-4 and EDG-7. The EDG receptors couple to multiple G proteins to signal through Ras, MAP kinase, Rho, Phospholipase C or other tyrosine kinases, which lead to cell survival, growth, migration and differentiation. EDG-1 signals through Gi proteins to activate Akt and is expressed in glioma cells. EDG-2 is expressed in brain, especially in white matter tract regions, while EDG-3 is expressed in cardiovascular tissue and in cerebellum. EDG-4 is highly expressed on leukocytes and brain, and EDG-5 has wide tissue distribution, including cardiovascular tissue and brain.
EDG6 is a Lysophospholipid/Lysosphingolipid Receptor, may regulate lymphocyte cell signaling. EDG6 is activated by sphingosine-1-phosphate.

General readings

Matsuyuki, H.,et al.(2006).Cell Mol Immunol.3(6):429-437.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EDG6 / S1P4 antibody

Anti-EDG6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. Rabbit Purified Hu E, P
50 µg / €345.00
  OriGene Technologies, Inc.

EDG6 / S1P4 antibody

Western blot analysis using EDG-6 antibody on EDG-6 control lysate at 5 µg/ml without (-) and with (+) specific blocking peptide. Rabbit Purified Hu WB
0.1 mg / €570.00
  Acris Antibodies GmbH

EDG6 / S1P4 antibody

EDG6 / S1P4 Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

EDG6 / S1P4 (C-term) antibody

Anti-S1PR4 / EDG6 antibody IHC of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Ms P
50 µg / €345.00
  OriGene Technologies, Inc.

EDG6 / S1P4 antibody

Anti-S1PR4 / EDG6 antibody IHC of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €345.00
  OriGene Technologies, Inc.

EDG6 / S1P4 antibody

Anti-S1PR4 / EDG6 antibody IHC of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 9.6 ug/ml. Rabbit IgG Purified Hst, Hu, Mky, Ms, Rt
50 µg / €345.00
  OriGene Technologies, Inc.

EDG6 / S1P4 antibody

Predicted band size: 42 kDa. Positive control: Rat kidney tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 50 ug per lane Primary antibody: 1/800 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 20 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

EDG6 / S1P4 antibody

Predicted band size: 42 kDa. Positive control: Rat kidney tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 50 ug per lane Primary antibody: 1/250 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 20 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

EDG6 / S1P4 antibody

Western Blot: EDG6 Antibody [TA336987] - Analysis of EDG6 in Jurkat cell lysate in the 1) absence and 2) presence of immunizing peptide and 3) RAW using TA336987 at 4.0 ug/ml. Rabbit Purified Hu, Ms ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EDG6 / S1P4 antibody

EDG6 / S1P4 Mouse IgG1 1 FITC Hu F, WB
0.1 mg / €570.00
  Acris Antibodies GmbH

EDG6 / S1P4 antibody

Figure 2. AM05330PU-N EDG6 antibody  staining of transiently transfected CHO cells by Immunofluorescence. Developed with Cy5 anti-Mouse, nuclei are stained with DAPI. Mouse IgG1 1 Purified Hu F, ICC/IF, WB
0.1 mg / €570.00
  Acris Antibodies GmbH

EDG6 / S1P4 antibody

Western blot (WB) analysis of EDG-6 antibody (Cat.-No.: AP01255PU-N) in extracts from K562 cells. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

EDG6 / S1P4 antibody

EDG6 / S1P4 Rabbit IgG Purified Hu WB
0.1 mg / €570.00
  Acris Antibodies GmbH

EDG6 / S1P4 antibody

EDG6 / S1P4 Rabbit IgG Purified Hu WB
0.1 mg / €570.00
  Acris Antibodies GmbH

EDG6 / S1P4 antibody

Western Blot analysis of S1PR4 expression in transfected 293T cell line (H00008698-T02) by S1PR4 MaxPab polyclonal antibody.

Lane 1: EDG6 transfected lysate(42.24 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

EDG6 / S1P4 antibody

IF on transiently transfected CHO cells. Developed with S1PR4 monoclonal antibody, clone 1 ( Cat # MAB2018 ), nucleiare stained with DAPI. Hu
0.1 mg / €640.00
  Abnova Taiwan Corp.

EDG6 / S1P4 antibody

Western blot analysis using S1PR4 polyclonal antibody ( Cat # PAB10364 ) on McA-RH7777 cells transfected with S1PR4 protein in the presence (lane 1) and absence (lane 2) of specific blocking peptide. Rabbit Hu WB
0.1 mg / €640.00
  Abnova Taiwan Corp.

EDG6 / S1P4 antibody

Immunofluorescence analysis of HepG2 cells, using EDG6 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

EDG6 / S1P4 antibody

Immunofluorescence analysis of HepG2 cells, using EDG6 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

EDG6 / S1P4 antibody

Immunofluorescence analysis of A549 cells, using EDG6 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF
50 µg / €205.00
  Assay Biotech

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