EGFL7 antibody

Principal name

EGFL7 antibody

Alternative names for EGFL7 antibody

EGF-like protein 7, EGF like protein 7, VE-statin, NOTCH4-like protein, Zneu1, MEGF7, UNQ187, PRO1449, Epidermal growth factor-like protein 7, Multiple epidermal growth factor-like domains protein 7, Multiple EGF-like domains protein 7, Vascular endothelial statin

SwissProt ID

Q6AZ60 (Rat), Q9QXT5 (Mouse), Q9UHF1 (Human)

Gene ID

51162 (EGFL7), 353156 (Egfl7)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Immunoprecipitation (IP)

Background of EGFL7 antibody

EGFL7 (epidermal growth factor-like domain 7) is a secreted angiogenic factor that is highly conserved in vertebrates. Most secreted angiogenic signaling molecules, including VEGF and FGF-2, are mainly expressed by non-endothelial cell types such as fibroblasts. In contrast, EGFL7 is unique because it is almost exclusively expressed by and acts on endothelial cells. EGFL7 expression is highest when the endothelium is in an active, proliferating state. This factor acts as a chemo-attractant for endothelial cells and binds to components of the extracellular matrix. In vivo, EGFL7 is important for regulating tubulogenesis in Zebrafish and for controlling vascular patterning and integrity in mice. Its function in blood vessel development is mediated, at least in part, through modulation of Notch signaling. There is evidence that support a role for EGFL7 in developmental and postnatal angiogenesis as well as a potential role for EGFL7 in vascular repair.
EGFL7, also known as VE-Statin (Vascular endothelial Statin), is a endothelial-specific protein that is a marker for progenitor, embryonic and adult endothelial cells. Mature soluble EGFL7/VE-Statin is a 41 kDa protein containing an N-terminal cysteine rich EMI domain, followed by two EGF-like domains and a coiled-coil region. EGFL7/VE-Statin inhibits PDGF-BB-induced smooth muscle cell migration. The amino acid sequence of human EGFL7/VE-Statin is 80% identical to that of mouse EGFL7/VE-Statin.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EGFL7 antibody

Immunohistochemical staining (ICC) of Human and Mouse EGFL7 constructs overexpressed in HEK293T cell with anti-human VE-Statin/EGFL-7 Antibody Cat.-No DP3521.The experiment was performed by Dr. Mirko HH Schmidt, Institute of Neurology (Edinger Institute), Neuroscience Center, J.W. Goethe University Scholl of Medicine, Heinrich-Hoffmann-Str. 7, D-60528 Frankfurt, Germany. Rabbit IgG Purified Hu C, ICC/IF, WB
0.2 mg / €370.00
  Acris Antibodies GmbH

EGFL7 antibody

Immunohistochemical staining (ICC) of Human and Mouse EGFL7 constructs overexpressed in HEK293T cell with anti-human VE-Statin/EGFL-7 Antibody Cat.-No DP3521.The experiment was performed by Dr. Mirko HH Schmidt, Institute of Neurology (Edinger Institute), Neuroscience Center, J.W. Goethe University Scholl of Medicine, Heinrich-Hoffmann-Str. 7, D-60528 Frankfurt, Germany. Rabbit IgG Purified Hu C, ICC/IF, WB
0.1 mg / €270.00
  Acris Antibodies GmbH

EGFL7 antibody

EGFL7 MaxPab rabbit polyclonal antibody. Western Blot analysis of EGFL7 expression in human placenta. Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

EGFL7 antibody

AP23785PU EGFL7 antibody staining of Human placenta. Rabbit IgG Purified Hu P
0.5 ml / €360.00
  Acris Antibodies GmbH

EGFL7 antibody

AP23785PU EGFL7 antibody staining of Human placenta. Rabbit IgG Purified Hu P
1 ml / €520.00
  Acris Antibodies GmbH

EGFL7 antibody

AP23785PU EGFL7 antibody staining of Human placenta. Rabbit IgG Purified Hu P
0.1 ml / €190.00
  Acris Antibodies GmbH

EGFL7 antibody

Predicted cell location: Cytoplasm. Positive control: Human thyroid cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human thyroid cancer tissue using EGFL7 antibody at dilution 1/20, on the right is treated with the fusion protein. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

EGFL7 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY EGFL7 (RC218849, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-EGFL7.(1:2000) Mouse IgG1 OTI2B5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

EGFL7 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY EGFL7 (RC218849, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-EGFL7.(1:2000) Mouse IgG1 OTI4A5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

EGFL7 antibody

AP33497PU-N (1µg/ml) staining of Heart (A), Kidney (B) and Lung (C) lysates (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €340.00
  Acris Antibodies GmbH

EGFL7 (C-term) antibody

Immunocytochemical staining (ICC) of human and mouse EGFL7: Left column: DAPI; Middle column:  Staining with anti-mouse EGFL7 antibody Cat.-No. AP60004PU-N; Right column: Merge. Performed by Dr. Frank Bicker, Research group „Molecular Signal Transduction“ (Prof. Dr. Mirko HH Schmidt), Institute of Microscopic Anatomy and Neurobiology, University Mainz, Germany. Rabbit IgG Purified Ms ICC/IF, IP, WB
0.2 mg / €370.00
  Acris Antibodies GmbH

EGFL7 (C-term) antibody

Immunocytochemical staining (ICC) of human and mouse EGFL7: Left column: DAPI; Middle column:  Staining with anti-mouse EGFL7 antibody Cat.-No. AP60004PU-N; Right column: Merge. Performed by Dr. Frank Bicker, Research group „Molecular Signal Transduction“ (Prof. Dr. Mirko HH Schmidt), Institute of Microscopic Anatomy and Neurobiology, University Mainz, Germany. Rabbit IgG Purified Ms ICC/IF, IP, WB
0.1 mg / €270.00
  Acris Antibodies GmbH

EGFL7 (C-term) antibody

Immunocytochemical staining (ICC) of human and mouse EGFL7: Left column: DAPI; Middle column: Staining with anti-human EGFL7 antibody Cat.-No. AP60007PU; Right column: Merge. Performed by Dr. Frank Bicker, Research group „Molecular Signal Transduction“ (Prof. Dr. Mirko HH Schmidt), Institute of Microscopic Anatomy and Neurobiology, University Mainz, Germany. Rabbit IgG Purified Hu C, ICC/IF, IP, WB
0.2 mg / €370.00
  Acris Antibodies GmbH

EGFL7 (C-term) antibody

Immunocytochemical staining (ICC) of human and mouse EGFL7: Left column: DAPI; Middle column: Staining with anti-human EGFL7 antibody Cat.-No. AP60007PU; Right column: Merge. Performed by Dr. Frank Bicker, Research group „Molecular Signal Transduction“ (Prof. Dr. Mirko HH Schmidt), Institute of Microscopic Anatomy and Neurobiology, University Mainz, Germany. Rabbit IgG Purified Hu C, ICC/IF, IP, WB
0.1 mg / €270.00
  Acris Antibodies GmbH

EGFL7 (C-term) antibody

Immunocytochemical staining (ICC) of human and mouse EGFL7: Left column: DAPI; Middle column: Staining with antihuman EGFL7 antibody Cat.-No. AP60008PU; Right column: Merge. Performed by Dr. Frank Bicker, Research group „Molecular Signal Transduction“ (Prof. Dr. Mirko HH Schmidt), Institute of Microscopic Anatomy and Neurobiology, University Mainz, Germany. Rabbit IgG Purified Hu C, ICC/IF, IP, WB
0.2 mg / €370.00
  Acris Antibodies GmbH

EGFL7 (C-term) antibody

Immunocytochemical staining (ICC) of human and mouse EGFL7: Left column: DAPI; Middle column: Staining with antihuman EGFL7 antibody Cat.-No. AP60008PU; Right column: Merge. Performed by Dr. Frank Bicker, Research group „Molecular Signal Transduction“ (Prof. Dr. Mirko HH Schmidt), Institute of Microscopic Anatomy and Neurobiology, University Mainz, Germany. Rabbit IgG Purified Hu C, ICC/IF, IP, WB
0.1 mg / €270.00
  Acris Antibodies GmbH

EGFL7 antibody

EGFL7 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

EGFL7 antibody

EGFL7 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

EGFL7 antibody

EGFL7 MaxPab rabbit polyclonal antibody. Western Blot analysis of EGFL7 expression in human placenta. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

EGFL7 antibody

Detection limit for recombinant GST tagged EGFL7 is approximately 0.03ng/ml as a capture antibody. Mouse IgG 2H6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

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