EIF2B / EIF2S2 antibody

Principal name

EIF2B / EIF2S2 antibody

Alternative names for EIF2B / EIF2S2 antibody

Eukaryotic translation initiation factor 2 subunit 2, eIF-2-beta, eIF2-beta, Eukaryotic translation initiation factor 2 subunit beta

SwissProt ID

P20042 (Human), P41035 (Rabit), Q5E9D0 (Bovin), Q99L45 (Mouse)

Gene ID

8894 (EIF2S2), 67204 (Eif2s2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken), Rb (Rabbit), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of EIF2B / EIF2S2 antibody

Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Olsen,J.V., (2006) Cell 127 (3), 635-648

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CRISPR

Catalog No. Species Donor Vector  

Eif2s2 - mouse gene knockout kit via CRISPR

Eif2s2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

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