eIF4G2 / DAP5 antibody

Principal name

eIF4G2 / DAP5 antibody

Alternative names for eIF4G2 / DAP5 antibody

eIF-4-gamma 2, p97, AAG1, NAT1, FLJ41344, Death-associated protein 5, Eukaryotic translation initiation factor 4 gamma 2

SwissProt ID

O73777 (Chick), P78344 (Human), P79398 (Rabit), Q58EZ2 (Human), Q62448 (Mouse), Q95L46 (Bovin)

Gene ID

1982 (EIF4G2), 13690 (Eif4g2)

Available reactivities

Hu (Human), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rb (Rabbit), African clawed frog, Ze (Zebrafish), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of eIF4G2 / DAP5 antibody

Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. EIF4G2 shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, EIF4G2 functions as a general repressor of translation by forming translationally inactive complexes. Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

General readings

NIH MGC Project, (2001) Direct Submission

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

eIF4G2 / DAP5 antibody

  Rabbit Polyclonal antibody to DAP5 (eukaryotic translation initiation factor 4 gamma, 2)  
Sample (50 ug of whole cell lysate). A: Mouse brain. 5% SDS PAGE. TA308779 diluted at 1:500. Rabbit IgG Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

eIF4G2 / DAP5 antibody

  Rabbit polyclonal anti-EIF4G2 antibody  
Western blot analysis of extracts from A549 cells, using EIF4G2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

eIF4G2 / DAP5 antibody

  Anti-EIF4G2 Rabbit Polyclonal Antibody  
Western blot analysis of Hela and HepG2 cell using TA321342(EIF4G2 Antibody) at dilution 1/500 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

eIF4G2 / DAP5 antibody

  Anti-EIF4G2 Rabbit Polyclonal Antibody  
Western blot analysis of Hela, HepG2 and NIH/3T3 cell using TA321343(EIF4G2 Antibody) at dilution 1/300 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

eIF4G2 / DAP5 antibody

  Mouse Monoclonal DAP5 Antibody (39C534.1)  
Western Blot: DAP5 Antibody (39C534.1) [TA336576] - Analysis of TA336576 (1ug) on 15 ug of total cell lysate from Jurkat cells. Mouse IgG1 39C534.1 Purified Hu, Ms F, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

eIF4G2 / DAP5 antibody

  Rabbit Polyclonal Anti-EIF4G2 Antibody  
WB Suggested Anti-EIF4G2 Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

eIF4G2 / DAP5 antibody

  Rabbit Polyclonal Anti-EIF4G2 Antibody  
WB Suggested Anti-EIF4G2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: 721_B cell lysate; EIF4G2 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

eIF4G2 / DAP5 (796-812) antibody

AM08365PU-N eIF4G2 / DAP5 antibody staining of Formalin-Fixed Paraffin-Embedded Human Brain, cortex at 10 µg/ml followed by biotinylated anti-Mouse IgG secondary antibody, Alkaline Phosphatase-Streptavidin and Chromogen. Mouse IgG1 39C534.1 Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

eIF4G2 / DAP5 antibody

Western blot (WB) analysis of DAP-5 antibody (Cat.-No.: AP20486PU-N) in extracts from A549 cells. Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

eIF4G2 / DAP5 (1-204) antibody

IHC Image of AP23160PU-N
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Bov, Hu, Ms, Rb, Rt, Ze P, WB
50 µl / €470.00
  Acris Antibodies GmbH

eIF4G2 / DAP5 antibody

Western blot analysis of extracts from A549 cells, using EIF4G2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €230.00
  Assay Biotech

eIF4G2 / DAP5 antibody

Western blot analysis of extracts from A549 cells, using EIF4G2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

EIF4G2 - human gene knockout kit via CRISPR

EIF4G2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

EIF4G2 - human gene knockout kit via CRISPR

EIF4G2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

EIF4G2 - human gene knockout kit via CRISPR

EIF4G2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

EIF4G2 - human gene knockout kit via CRISPR

EIF4G2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Eif4g2 - mouse gene knockout kit via CRISPR

Eif4g2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Eif4g2 - mouse gene knockout kit via CRISPR

Eif4g2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Eif4g2 - mouse gene knockout kit via CRISPR

Eif4g2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Eif4g2 - mouse gene knockout kit via CRISPR

Eif4g2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

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