EIF5A2 antibody

Principal name

EIF5A2 antibody

Alternative names for EIF5A2 antibody

eIF-5A-2, eIF-5A2, Eukaryotic translation initiation factor 5A-2, Eukaryotic translation initiation factor 5A-2

SwissProt ID

P23301 (Yeast), Q07460 (Chick), Q20751 (Caeel), Q8BGY2 (Mouse), Q93VP3 (Arath), Q9GZV4 (Human), Q9UST4 (Schpo)

Gene ID

56648 (EIF5A2), 208691 (Eif5a2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), GP (Guinea Pig), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), EPair for Elisa (EPair), Immunoprecipitation (IP), Flow Cytometry (F), Paraffin Sections (P), Frozen Sections (C)

Background of EIF5A2 antibody

Eukaryotic translation initiation factor 5A2 (eIF5A-2), a recently discovered oncogene member of the eIF5A family, is an mR-binding protein implicated in the translation elongation process and it exerts a critical role at the level of mR turnover, probably acting downstream of decapping. eIF5A-2 involves in actin dymics, progression of cell cycle, mR decay, stress response sigling as well as in the preservation of cellular wall's integrity. eIF5A-2 mediates the effects of polyamines on neurol process extension/survival, and has been suggested to play a role in CNS development/functions as well as differentiation of skeletal muscle stem cells. eIF5A-2 has been reported to localize in nucleus, cytoplasm and ER membranes of cells, and hypusine modification, a posttranslatiol modification of at least one lysine residue to form hypusine [N-epsilon-(4-aminobutyl)lysine], as well as apoptosis impacts eIF5A-2 localization in various cellular compartments. eIF5A-2 exhibits weak expression levels in lungs, testis and brain cells, however, its elevated expression has been shown to be associated with the presence of cancer metastases in colon, ovarian, lung and bladder cancers. In vitro and in vivo studies have revealed that overexpression of eIF5A-2 could significantly enhance the malignt tumor cell motility/invasiveness, whereas, its intracellular depletion leads to inhibition of cell growth as well as induction of apoptosis.

General readings

Guan XY., et al. (2010) Hepatology. 51(4):1255-63.
Luk JM., et al. (2009) Int J Cancer. 127(4):968-76.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EIF5A2 antibody

  EIF5A2 mouse monoclonal antibody, clone OTI6G7 (formerly 6G7)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-EIF5A2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA505100) Mouse IgG1 OTI6G7 Purified Hu F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

EIF5A2 antibody

  Rabbit Polyclonal antibody to EIF5A2 (eukaryotic translation initiation factor 5A2)  
Sample(30ug of whole cell lysate). A: 293T. B: A431 . C: H1299. D: HeLa S3 . E: Hep G2 . F: MOLT4 . G: Raji . 15% SDS PAGE. TA308787 diluted at 1:1000 Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

EIF5A2 antibody

  Rabbit Polyclonal eIF5A2 Antibody  
Western Blot: eIF5A2 Antibody [TA336587] - Detection of endogenous and FLAG-tagged eIF5A1 in HeLa cells using NB 200-133 at a 1:1000 dilution Rabbit Purified Hu C, E, IP, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EIF5A2 antibody

  Rabbit Polyclonal Anti-EIF5A2 Antibody - N-terminal region  
WB Suggested Anti-EIF5A2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Liver Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

EIF5A2 antibody

  EIF5A2 mouse monoclonal antibody, clone OTI2E9 (formerly 2E9)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY EIF5A2 (RC206249, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-EIF5A2. Mouse IgG1 OTI2E9 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

EIF5A2 antibody

  EIF5A2 mouse monoclonal antibody, clone OTI6F7 (formerly 6F7)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-EIF5A2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA505147) Mouse IgG1 OTI6F7 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CRISPR

Catalog No. Species Donor Vector  

EIF5A2 - human gene knockout kit via CRISPR

EIF5A2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

EIF5A2 - human gene knockout kit via CRISPR

EIF5A2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

EIF5A2 - human gene knockout kit via CRISPR

EIF5A2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

EIF5A2 - human gene knockout kit via CRISPR

EIF5A2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Eif5a2 - mouse gene knockout kit via CRISPR

Eif5a2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Eif5a2 - mouse gene knockout kit via CRISPR

Eif5a2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Eif5a2 - mouse gene knockout kit via CRISPR

Eif5a2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Eif5a2 - mouse gene knockout kit via CRISPR

Eif5a2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

EIF5A2

  Recombinant protein of human eukaryotic translation initiation factor 5A2 (EIF5A2)  
EIF5A2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

EIF5A2 (1-153, His-tag)

EIF5A2 Human Purified > 85 % by SDS - PAGE E. coli
0.25 mg / €1,000.00
  Acris Antibodies GmbH

EIF5A2 (1-153, His-tag)

EIF5A2 Human Purified > 85 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

EIF5A2 overexpression lysate

EIF5A2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Eif5a2 (GFP-tagged) - Mouse eukaryotic translation initiation factor 5A2 (Eif5a2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Eif5a2 (GFP-tagged) - Mouse eukaryotic translation initiation factor 5A2 (Eif5a2), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Eif5a2 (Myc-DDK-tagged) - Mouse eukaryotic translation initiation factor 5A2 (Eif5a2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Eif5a2 (Myc-DDK-tagged) - Mouse eukaryotic translation initiation factor 5A2 (Eif5a2), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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