EIF6 / ITGB4BP antibody

Principal name

EIF6 / ITGB4BP antibody

Alternative names for EIF6 / ITGB4BP antibody

eIF-6, EIF3A, B4 integrin interactor, CAB, p27(BBP), B(2)GCN homolog, Eukaryotic translation initiation factor 6

SwissProt ID

P56537 (Human), Q9TU47 (Bovin)

Gene ID

3692 (EIF6), 3692581 (Q3JJ17)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Frozen Sections (C)

Background of EIF6 / ITGB4BP antibody

EIF6 (Eukaryotic Translation Initiation Factor 6), also called EIF3A or ITGB4BP, is a human gene. By fluorescence in situ hybridization, Sanvito et al. (1998) mapped the ITGB4BP gene to 20q11.2. Ceci et al. (2003) demonstrated that the ribosomal 60S subunit is activated by release of EIF6. In the cytoplasm, EIF6 is bound to free 60S but not to 80S subunits. Furthermore, EIF6 interacts in the cytoplasm with RACK1, a receptor for activated protein kinase C. Gandin et al. (2008) demonstrated that mammalian eIF6 is required for efficient initiation of translation in vivo. Eif6-null mouse embryos were lethal at preimplantation. Heterozygous mice had 50% reduction of eIF6 levels in all tissues, and showed reduced mass of hepatic and adipose tissues due to a lower number of cells and to impaired G1/S cell cycle progression.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EIF6 / ITGB4BP antibody

Predicted band size: 27 kDa . Positive control: COLO320 cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

EIF6 / ITGB4BP antibody

Western blot analysis of extracts of various cell lines, using EIF6 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

EIF6 / ITGB4BP antibody

ITGB4BP polyclonal antibody (A01), Lot # 051122JC01 Western Blot analysis of ITGB4BP expression in HL-60 ( Cat # L014V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

EIF6 / ITGB4BP (C-term) antibody

Human Fetal liver; WB Suggested Anti-EIF6 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Fetal Liver; EIF6 antibody - C-terminal region (ARP61387_P050) in Human Fetal liver cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

EIF6 / ITGB4BP (N-term) antibody

Human HeLa; WB Suggested Anti-EIF6 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Hela Whole Cell. EIF6 is supported by BioGPS gene expression data to be expressed in HeLa.; EIF6 antibody - N-terminal region (ARP61388_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

EIF6 / ITGB4BP antibody

EIF6 / ITGB4BP Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

EIF6 / ITGB4BP antibody

Western Blot: integrin beta 4 binding protein Antibody [NBP1-52640] - Affinity purified rabbit anti-eIF6 antibody  used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate. eIF6 was also immunoprecipitated by rabbit anti-eIF6 antibody NBP1-52641, which recognizes a downstream epitope. Rabbit Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

EIF6 / ITGB4BP antibody

Western Blot: integrin beta 4 binding protein Antibody [NBP1-52641] - Affinity purified rabbit anti-eIF6 antibody  used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate.  eIF6 was also immunoprecipitated by rabbit anti-eIF6 antibody NBP1-52640, which recognizes an upstream epitope. Rabbit Aff - Purified Hu, Ms IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

EIF6 / ITGB4BP (transcript variant 2)

EIF6 / ITGB4BP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

EIF6 / ITGB4BP

EIF6 / ITGB4BP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

EIF6 / ITGB4BP

EIF6 / ITGB4BP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

EIF6 / ITGB4BP

EIF6 / ITGB4BP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

EIF6 / ITGB4BP

EIF6 / ITGB4BP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

EIF6 overexpression lysate

EIF6 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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