ELP1 / IKBKAP antibody

Principal name

ELP1 / IKBKAP antibody

Alternative names for ELP1 / IKBKAP antibody

Elongator complex protein 1, IKAP, p150, IkappaB kinase complex-associated protein, IKK complex-associated protein

SwissProt ID

O95163 (Human), Q2TAQ1 (Xenla), Q7TT37 (Mouse), Q8VHU4 (Rat), Q8WND5 (Rabit), Q9CT81 (Mouse)

Gene ID

8518 (IKBKAP)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of ELP1 / IKBKAP antibody

IKAP was initially identified as a scaffold protein of the IkappaB kinase complex that could bind to IKKalpha, IKKbeta, NF-kappaB, and the NF-kappaB-inducing kinase (NIK), although later evidence has cast doubt on this. More recent reports show that mutations in IKAP such as a frameshift leading to a truncated protein or a missense mutation that leads to defective phosphorylation are responsible for the autosomal recessive genetic disease familial dysautonomia (FD). Reports indicating that it forms part of the RNA polymerase II transcription elongation complex suggest that this disease may be due to compromised transcription elongation. More recently, it was shown that IKAP associates with c-Jun N-terminal kinase (JNK) and could specifically enhance JNK activation induced by the upstream JNK activators MEKK1 and ASK1, indicating another possible cause for FD. At least two isoforms of IKAP are known two exist.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ELP1 / IKBKAP antibody

Western blot analysis of IKAP in A-20 cell lysate with IKAP antibody at in (A) 0.5, and (B) 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ELP1 / IKBKAP antibody

Western Blot: IKBKAP Antibody [TA336679] - Analysis of IKBKAP in Interleukin-1-stimulated 293 cells using this antibody at 1:500 dilution. Rabbit Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ELP1 / IKBKAP antibody

Western Blot: IKBKAP Antibody [TA336680] - Analysis of IKBKAP in Interleukin-1-stimulated 293 cells using TA336680 at 1:500 dilution Rabbit Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ELP1 / IKBKAP (148-161) antibody

Lung, nerve: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Bear, Bov, Bt, Can, Chk, Elephant, Eq, Fi, Hst, Hu, Mky, Ms, Op, Platypus, Por, Prim, Rb, Rt, Tr E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

ELP1 / IKBKAP (C-term) antibody

Figure 2. Formalin-Fixed Paraffin-Embedded (FFPE) on Testis. Rabbit Purified Hu, Ms ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

ELP1 / IKBKAP Control Peptide

ELP1 / IKBKAP
50 µg / €160.00
  Acris Antibodies GmbH

ELP1 / IKBKAP antibody

Immunoperoxidase of monoclonal antibody to IKBKAP on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml] Mouse IgG1 6G9 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ELP1 / IKBKAP (C-term) antibody

Western blot of  IKAP (1:500) in HEK293 cells stimulated with interleukin-1 Rabbit Purified Hu WB
0.1 ml / €270.00
  Neuromics Antibodies

ELP1 / IKBKAP antibody

Western Blot: IKBKAP Antibody [NBP1-71918]- Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells.   Affinity purified rabbit anti-IKAP antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate.  IKAP was also immunoprecipitated by rabbit anti-IKAP antibody NBP1-71919, which recognizes a downstream epitope. Rabbit Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

ELP1 / IKBKAP antibody

Western Blot: IKBKAP Antibody [NBP1-71919]-Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells.    Affinity purified rabbit anti-IKAP antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate.  IKAP was also immunoprecipitated by rabbit anti-IKAP antibody NBP1-71918_x000d_
, which recognizes an upstream epitope. Rabbit Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

ELP1 / IKBKAP antibody

Immunohistochemistry-Paraffin: IKBKAP Antibody [NBP1-76788] - A-20 cells with IKAP antibody at 1 u/mL. _x000d_ Rabbit Aff - Purified Hu, Ms E, ICC/IF, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ELP1 / IKBKAP

ELP1 / IKBKAP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

ELP1 / IKBKAP

ELP1 / IKBKAP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

ELP1 / IKBKAP

ELP1 / IKBKAP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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