EMAP4 / EML4 antibody

Principal name

EMAP4 / EML4 antibody

Alternative names for EMAP4 / EML4 antibody

Ropp 120, EMAP-4, C2orf2, EMAPL4, Echinoderm microtubule-associated protein-like 4, Restrictedly overexpressed proliferation-associated protein

SwissProt ID

Q2TAF3 (Xenla), Q3UMY5 (Mouse), Q9HC35 (Human)

Gene ID

27436 (EML4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of EMAP4 / EML4 antibody

Microtubules are components of the Actin cytoskeleton that play crucial roles in cell morphogenesis, cell motility, spindle formation and chromosome movements. Echinoderm microtubule-associated (EML) proteins function to modify the assembly dynamics of microtubules. EML4 (Echinoderm microtubule-associated protein-like 4), also known as EMAPL4, ELP120, C2orf2 or ROPP120, is a 981 amino acid cytoplasmic protein that contains nine WD repeats. Expressed at high levels during mitosis, EML4 is thought to modify the assembly dynamics of microtubules, specifically altering microtubules to become longer and more flexible. Due to a chromosomal inversion with chromosome 2p, EML4 may exist as a fusion protein with ALK (anaplastic lymphoma receptor tyrosine kinase), producing an EML4-ALK fusion complex that plays a role in the pathogenesis of lung cancer.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EMAP4 / EML4 antibody

Immunoperoxidase of monoclonal antibody to EML4 on formalin-fixed paraffin-embedded human prostate cancer. [antibody concentration 10 ug/ml] Mouse IgG1 3C10 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

EMAP4 / EML4 antibody

EMAP4 / EML4 Mouse IgG1 2F2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

EMAP4 / EML4 antibody

Immunohistochemistry-Paraffin: EML4 Antibody [NBP1-05973] - FFPE section of human lung adenocarcinoma.   Affinity purified rabbit anti-EML4 used at a dilution of 1:250.  Detection: DAB staining using Immunohistochemistry Accessory Kit Rabbit IgG Aff - Purified Hu IP, P, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

EMAP4 / EML4 antibody

Western Blot and Immunoprecipitation: EML4 Antibody [NBP1-05974]-  Whole cell lysate from HeLa cells. EML4 was also immunoprecipitated by rabbit anti-EML4 antibody NBP1-05973. Rabbit IgG Aff - Purified Hu IP, P, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

EMAP4 / EML4 antibody

Immunohistochemistry-Paraffin: EML4 Antibody [NBP1-86805] - Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

EMAP4 / EML4 (transcript variant 1)

EMAP4 / EML4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

EMAP4 / EML4

EMAP4 / EML4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

EMAP4 / EML4

EMAP4 / EML4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

EML4 overexpression lysate

EML4 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

9 Item(s)

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