ENAC alpha / SCNN1A antibody

Principal name

ENAC alpha / SCNN1A antibody

Alternative names for ENAC alpha / SCNN1A antibody

Alpha-ENaC, ENaCA, SCNN1, SCNEA, Alpha-NaCH, Amiloride-sensitive sodium channel subunit alpha, Epithelial Na(+) channel subunit alpha, Nonvoltage-gated sodium channel 1 subunit alpha

SwissProt ID

O97741 (Rabit), P37088 (Human), P37089 (Rat), P51167 (Xenla), P55270 (Bovin), Q61180 (Mouse), Q92075 (Chick), Q9R1N2 (Cavpo)

Gene ID

6337 (SCNN1A), 25122 (Scnn1a)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of ENAC alpha / SCNN1A antibody

The DEG/EC family consists of + selective channels. They are characterized by 2 transmembrane domains with a large extracellular loop, important for channel activity and intracellular N-and C-termini which are important for channel gating and for interacting with regulatory proteins respectively. EC is localized to the apical side of polarized epithelial cells like those in the kidney, lung, and distal colon and is responsible for maintaining proper + balance. This channel is formed by oligomerization of three subunits, α, β, and γ usually with the α2β1γ1 combition. In addition, the a subunit which is essential for channel activity undergoes phosphorylation in its C-termil by SGK1 (serum and glucocorticoid-induced kise 1) which is known to activate the channel at the plasma membrane. Pseudohypoaldosteronism type 1 (PHA-1) has an early onset and is depicted by severe dehydration, hypotremia and hyperkalemia. One form of the pathology is characterized by mutations in α, β, and γ subunits. The severity of the diseases depends on the loss of activity of the channel.

11 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ENAC alpha / SCNN1A antibody

ENAC alpha / SCNN1A Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ENAC alpha / SCNN1A (Center) antibody

Western blot analysis of SCNN1A Antibody (Center) (Cat. #TA325073) in WiDr cell line lysates (35ug/lane). SCNN1A (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

ENAC alpha / SCNN1A antibody

Western blot analysis of ENaC-Alpha in rat kidney tissue using a 1:1000 dilution of the antibody Rabbit Purified Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ENAC alpha / SCNN1A antibody

Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) kidney lysate:1, 2. Anti-ENaCa (extracellular) antibody , (1:200).3, 4. Anti-ENaCa (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

ENAC alpha / SCNN1A antibody

ENAC alpha / SCNN1A Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

ENAC alpha / SCNN1A antibody

ENAC alpha / SCNN1A Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €400.00
  Novus Biologicals Inc.

ENAC alpha / SCNN1A antibody

ENAC alpha / SCNN1A Rabbit Purified Rt P
0.1 ml / €400.00
  Novus Biologicals Inc.

ENAC alpha / SCNN1A antibody

ENAC alpha / SCNN1A Rabbit Purified Hu P
0.5 mg / €400.00
  Novus Biologicals Inc.

ENAC alpha / SCNN1A antibody

Immunohistochemistry-Paraffin: epithelial Sodium Channel alpha Antibody [NBP1-84845] - Immunohistochemical staining of human kidney shows membranous positivity in cells in tubules. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

SCNN1A overexpression lysate

SCNN1A overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

SCNN1A overexpression lysate

SCNN1A overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

11 Item(s)

per page
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