Endomucin antibody

Principal name

Endomucin antibody

Alternative names for Endomucin antibody

EMCN, EMCN2, MUC14, Endomucin-2, Mucin-14, Gastric cancer antigen Ga34

SwissProt ID

Q6AY82 (Rat), Q9R0H2 (Mouse), Q9ULC0 (Human)

Gene ID

51705 (EMCN), 59308 (Emcn)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Rat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP), Frozen Sections (C), Flow Cytometry (F)

Background of Endomucin antibody

As a typical mucin-like glycoprotein, endomucin has a high content of serine and threonine residues, suggesting strong O-glycosylation; the sensitivity to O-sialoglycoprotein endopeptidase indicates that endomucin is also a sialomucin.
Endomucin is an endothelial-specific sialomucin. It is a constitutively expressed endothelial cell surface protein that is found on all venules but is absent from high endothelial venule cells (HEV) of peripheral and mesenteric lymph nodes as well as Peyer's patches, the specialized site for most efficient lymphocyte trafficking. This could indicate an anti-adhesive function of endomucin, as demonstrated for other sialomucins.
Mucosal addressin cell adhesion molecule 1 (MAdCAM-1) is another cell adhesion molecule that contains a mucin-like domain and is expressed on HEV in Peyer's patches, mesenteric lymph nodes and on venules in intestinal lamina propria. In the HEV of mesenteric lymph nodes, the mucin-like domain of a subpopulation of MAdCAM-1 molecules contains sulfated carbohydrate side chains that interact with L-selectin.
The presence of three putative protein kinase C phosphorylation sites in the cytoplasmic tail of endomucin indicates that endomucin has the capacity to be a signaling molecule.

General readings

Kinoshita M, et al. (2001) FEBS Lett 499 (1-2): 121-6.
Kuhn A., et al. (2002) J. Invest. Dermatol. 119:1388-1393

18 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Endomucin antibody

Sample (30 ug of whole cell lysate). A: A431 . 12% SDS PAGE. TA308287 diluted at 1:1000. Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Endomucin antibody

Immunofluorescence analysis of HepG2 cells, using Mucin-14 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

Endomucin antibody

Host: Rabbit; Target Name: EMCN; Sample Tissue: 293T Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Endomucin antibody

Endomucin Rat IgG2a V.7C7.1 Purified Ms C, IP, P, WB
0.1 mg / €300.00
  Acris Antibodies GmbH

Endomucin antibody

Western analysis using anti-mouse Endomucin antibody Cat.-No. AP60010PU. Sample was loaded in 15% SDS-polyacrylamide gel under reducing conditions. Lane 1: MWM (kDa); Lane 2: rm sEndomucin (250ng). Rabbit IgG Purified Ms F, WB
0.2 mg / €370.00
  Acris Antibodies GmbH

Endomucin antibody

Western analysis using anti-mouse Endomucin antibody Cat.-No. AP60010PU. Sample was loaded in 15% SDS-polyacrylamide gel under reducing conditions. Lane 1: MWM (kDa); Lane 2: rm sEndomucin (250ng). Rabbit IgG Purified Ms F, WB
0.1 mg / €270.00
  Acris Antibodies GmbH

Endomucin antibody

Immunofluorescence staining (green) of cryo-sections of adult mouse kidney (fixed 15 min in 4% PFA) with anti-mouse Endomucin antibody Cat.-No. AP60010PU-S (5?g/ml) and counter staining of nuclei with DAPI (blue). <i>Performed by the research group of Prof. Dr. J. Wilting and Dr. K. Buttler, University Göttingen, Germany.</i> Rabbit IgG Aff - Purified Ms C, ICC/IF, WB
50 µg / €280.00
  Acris Antibodies GmbH

Endomucin antibody

Immunofluorescence staining (green) of cryo-sections of Human foreskin (fixed 15 min in 4% PFA) with anti-Human Endomucin antibody Cat.-No AP60011PU (5 μg/ml) and counter staining of nuclei with DAPI (blue) and double staining wit anti-CD31 (right panel).Performed by the research group of Prof. Dr. J. Wilting and Dr. K. Buttler, University Göttingen, Germany. Rabbit IgG Purified Hu C, ICC/IF, WB
0.2 mg / €370.00
  Acris Antibodies GmbH

Endomucin antibody

Immunofluorescence staining (green) of cryo-sections of Human foreskin (fixed 15 min in 4% PFA) with anti-Human Endomucin antibody Cat.-No AP60011PU (5 μg/ml) and counter staining of nuclei with DAPI (blue) and double staining wit anti-CD31 (right panel).Performed by the research group of Prof. Dr. J. Wilting and Dr. K. Buttler, University Göttingen, Germany. Rabbit IgG Purified Hu C, ICC/IF, WB
0.1 mg / €270.00
  Acris Antibodies GmbH

Endomucin antibody

Immunofluorescence analysis of HepG2 cells, using Mucin-14 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
50 µg / €205.00
  Assay Biotech

Endomucin antibody

Immunofluorescence analysis of HepG2 cells, using Mucin-14 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
0.1 mg / €310.00
  Assay Biotech

Endomucin antibody

Immunohistochemistry-Paraffin: Mucin 14 Antibody [NBP1-92150] Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Endomucin (His-tag)

SDS-PAGE analysis of recombinant human soluble Endomucin produced in E. coli. Sample was loaded in 15% SDS-polyacrylamide gel under reducing condition and stained with Coomassie blue. Human Purified > 95 % by SDS-PAGE & Silver staining E. coli
20 µg / €460.00
  Acris Antibodies GmbH

Endomucin (19-190, His-tag)

Endomucin Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €730.00
  Acris Antibodies GmbH

Endomucin (19-190, His-tag)

Endomucin Human Purified > 90 % by SDS - PAGE E. coli
20 µg / €300.00
  Acris Antibodies GmbH

Endomucin (His-tag)

SDS-PAGE analysis of recombinant mouse soluble Endomucin produced in E. coli Cat.-No. AR60010PU-N. Sample was loaded in 15% SDS-polyacrylamide gel under reducing condition and stained with Silver staining. Mouse Purified > 95 % by SDS-PAGE & Silver staining E. coli
20 µg / €460.00
  Acris Antibodies GmbH

Endomucin

Endomucin Human
20 µg / €380.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

EMCN overexpression lysate

EMCN overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

per page
  • LinkedIn