Endonuclease G antibody

Principal name

Endonuclease G antibody

Alternative names for Endonuclease G antibody

ENDOG

SwissProt ID

O08600 (Mouse), P38447 (Bovin), Q14249 (Human)

Gene ID

2021 (ENDOG), 13804 (Endog)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of Endonuclease G antibody

The fragmentation of nuclear DNA is a hallmark of apoptotic cell death. The activities of caspase and nuclease are involved in the DNA fragmentation. Caspase-activated deoxyribonuclease (CAD), also termed DNA fragmentation factor (DFF40), is one such nuclease, and is capable of inducing DNA fragmentation and chromatin condensation after cleavage by caspase-3 of its inhibitor ICAD/DFF45. Caspase and CAD independent DNA fragmentation also exists. Recent studies demonstrated that another nuclease, endonuclease G (EndoG), is specifically activated by apoptotic stimuli and is able to induce nucleosomal fragmentation of DNA independently of caspase and DFF/CAD. EndoG is a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis.
The homologue of mammalian EndoG is the first mitochondrial protein identified to be involved in apoptosis in C. elegans.
EndoG also cleaves DNA in vitro.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Endonuclease G antibody

  ENDOG (Endonuclease G) mouse monoclonal antibody, clone OTI5F1 (formerly 5F1)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-ENDOG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504189) Mouse IgG1 OTI5F1 Purified Hu F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Endonuclease G antibody

  Rabbit Polyclonal EndoG Antibody  
Western blot analysis of EndoG in mouse (M) 3T3 and human (H) HepG2 cell lysates with EndoG antibody at 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €371.00
  OriGene Technologies, Inc.

Endonuclease G (51-140) antibody

  Mouse EndoG Monoclonal Antibody  
Western blot analysis of EndoG expression in HepG2 cell lysate with EndoG antibody at (A) 2.5 and (B) 5 ug/mL. Mouse IgG 7G1C10 Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €371.00
  OriGene Technologies, Inc.

Endonuclease G (51-140) antibody

  Mouse EndoG Monoclonal Antibody  
Western blot analysis of EndoG expression in HepG2 cell lysate with EndoG antibody at (A) 5 and (B) 10 ug/mL. Mouse IgG 7G1G10 Aff - Purified Hu, Ms E, WB
0.1 mg / €371.00
  OriGene Technologies, Inc.

Endonuclease G (51-140) antibody

  Mouse EndoG Monoclonal Antibody  
Western blot analysis of EndoG expression in HepG2 cell lysate with EndoG antibody at (A) 5 and (B) 10 ug/mL. Mouse IgG 7F2D7 Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €371.00
  OriGene Technologies, Inc.

Endonuclease G (51-140) antibody

  Mouse EndoG Monoclonal Antibody  
Western blot analysis of EndoG expression in HepG2 cell lysate with EndoG antibody at (A) 5 and (B) 10 ug/mL. Mouse IgG 7F2G10 Aff - Purified Hu, Rt E, WB
0.1 mg / €371.00
  OriGene Technologies, Inc.

Endonuclease G antibody

  Rabbit Polyclonal Anti-ENDOG Antibody  
WB Suggested Anti-ENDOG Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human Intestine Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rt, Ze WB
50 µg / €360.00
  OriGene Technologies, Inc.

Endonuclease G antibody

  Rabbit Polyclonal Anti-ENDOG Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using (ENDOG Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu E, P
0.1 ml / €335.00
  OriGene Technologies, Inc.

Endonuclease G (C-term) antibody

Western blot analysis of ENDOG Antibody (C-term) (AP17329PU-N) in 293, K562, Jurkat, NCI-H460 cell line lysates and mouse kidney tissues lysates(35 µg/lane). ENDOG (arrow) was detected using the purified Pab. Rabbit Hu, Ms WB
0.4 ml / €370.00
  OriGene Technologies GmbH

Endonuclease G antibody

AP26343PU-N: Western blot analysis of EndoG expression in rat kidney issue lysate. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €330.00
  OriGene Technologies GmbH

Endonuclease G antibody

EndoG - SP1412P staining of human pancreas with anti-EndoG at 15 µg/ml. Formalin fixed paraffin processed tissue. Rabbit Purified Hu, Ms, Rt P, WB
0.1 mg / €330.00
  OriGene Technologies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ENDOG (mGFP-tagged) - Human endonuclease G (ENDOG), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL

Lenti ORF particles, ENDOG (mGFP-tagged) - Human endonuclease G (ENDOG), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL  
200 µl / €989.00
  OriGene Technologies, Inc.

Lenti ORF particles, ENDOG (Myc-DDK tagged) - Human endonuclease G (ENDOG), nuclear gene encoding mitochondrial protein , 200 uL, >10^7 TU/mL

Lenti ORF particles, ENDOG (Myc-DDK tagged) - Human endonuclease G (ENDOG), nuclear gene encoding mitochondrial protein , 200 uL, >10^7 TU/mL  
200 µl / €886.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Endog (GFP-tagged) - Mouse endonuclease G (Endog), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL

Lenti ORF particles, Endog (GFP-tagged) - Mouse endonuclease G (Endog), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL  
200 µl / €907.00
  OriGene Technologies, Inc.

Lenti ORF particles, Endog (Myc-DDK-tagged) - Mouse endonuclease G (Endog), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL

Lenti ORF particles, Endog (Myc-DDK-tagged) - Mouse endonuclease G (Endog), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL  
200 µl / €804.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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