Endothelin-1 antibody

Principal name

Endothelin-1 antibody

Alternative names for Endothelin-1 antibody

PPET1, EDN1, ET1, HDLCQ7, EDN1, Preproendothelin-1

SwissProt ID

P05305 (Human), P09558 (Pig), P17322 (Bovin), P22387 (Mouse), P22388 (Rat), P29560 (Rabit), Q9BG76 (Sheep)

Gene ID

1906 (EDN1), 1466987 (acpP), 24323 (Edn1), 13614

Available reactivities

Hu (Human), Rt (Rat), Sh (Sheep), Bov (Bovine), Por (Porcine), Ms (Mouse)

Available hosts

Mouse, Rat, Sheep, Rabbit

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Radioimmunoassay (R), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), EPair for Elisa (EPair), ELISA (capture) (E(capture)), Flow Cytometry (F)

Background of Endothelin-1 antibody

The endothelins is a family of structurally and pharmacologically distinct peptides, which has been identified and sequenced in humans. Three isoforms of human endothelin have been identified: endothelin-1, -2, and -3. Endothelin-1 is a potent, 21-amino acid vasoconstrictor peptide produced by vascular endothelial cells. Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium having a key role in vascular homeostasis. Endothelins are implicated in vascular diseases of several organ systems, including the heart, general circulation and brain. Endothelins are proteins that constrict blood vessels and raise blood pressure. They are normally kept in balance by other mechanisms, but when they are over-expressed, they contribute to high blood pressure (hypertension) and heart disease.

General readings

This product has been used in:Nelson JB et al. Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancer. Cancer Res 56:663-8 (1996). PubMed PMID: 8630991
Traish AM et al. Monoclonal antibodies to human endothelin-1: characterization and utilization in radioimmunoassay and immunocytochemistry. Hybridoma 11:147-63 (1992). PubMed PMID: 1607212
Saenz de Tejada I et al. Endothelin: localization, synthesis, activity, and receptor types in human penile corpus cavernosum. Am J Physiol 261:H1078-85 (1991). PubMed PMID: 1656784
Rubanyi GM & Botelho LH Endothelins. FASEB J 5:2713-20 (1991). PubMed PMID: 1916094

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Endothelin 1+2+3 antibody

Endothelin 1+2+3 Rat IgG2b 3G10 Purified Hu C, R
0.1 mg / €340.00
  Acris Antibodies GmbH

Endothelin 1+2 antibody

Immunohistochemistry: Endothelin staining of paraffin human testis sections. The section was incubated with AP02091PU-S (1/700) for 24h and detected using a combination of the peroxidase-anti peroxidase (PAP) technique with the avidin-biotin-peroxidase complex method in its single variation. DAB was used as the chromogen. The section was counterstained with hematoxylin eosin. This antibody stains Leydig cells (LC). Sertoli cells (arrow) as well as mature spermatids (arrowheads). Original magnification: x450.
Ergun S et al, Anat Embryol, 1999, 199(3): 207-214. Sheep Purified Hu C, E, P, R
10 µg / €660.00
  Acris Antibodies GmbH

Endothelin-1 (Center) antibody

Formalin fixed and paraffin embedded human placenta tissue reacted with Endothelin-1 Antibody Cat.-No AP51364PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu F, ICC/IF, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Endothelin-1 antibody

Sample (30 ug of whole cell lysate). A: 293T. B: Hep G2 . 12% SDS PAGE. TA308770 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Endothelin-1 (C-term) antibody

Endothelin-1 Mouse IgG1 1C4 Purified Hu C, E, E(capture), R
0.1 mg / €320.00
  Acris Antibodies GmbH

Endothelin-1 antibody

Endothelin-1 Sheep Purified Hu C, E, P
20 µg / €660.00
  Acris Antibodies GmbH

Endothelin-1 antibody

Endothelin-1 Rabbit Serum Bov, Hu, Por E, P, R, WB
0.1 ml / €530.00
  Acris Antibodies GmbH

Endothelin-1 antibody

Endothelin-1 Rabbit Serum Bov, Hu, Por E, P, R, WB
20 µl / €180.00
  Acris Antibodies GmbH

Endothelin-1 (C-term) antibody

Formalin fixed and paraffin embedded human liver tissue reacted with Endothelin-1 Antibody (C-term) Cat.-No AP51365PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu ICC/IF, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Endothelin-1 antibody

EDN1 MaxPab polyclonal antibody. Western Blot analysis of EDN1 expression in human placenta. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Endothelin-1 antibody

Western Blot analysis of EDN1 expression in transfected 293T cell line (H00001906-T01) by EDN1 MaxPab polyclonal antibody.

Lane 1: EDN1 transfected lysate(24.40 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Endothelin-1 antibody

Western Blot analysis of EDN1 expression in transfected 293T cell line by EDN1 monoclonal antibody (M01), clone 3D6.

Lane 1: EDN1 transfected lysate(24 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 3D6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Endothelin-1 antibody

Endothelin-1 Mouse IgG1 403 Hu E, R
0.1 mg / €730.00
  Abnova Taiwan Corp.

Endothelin-1 antibody

Endothelin-1 Rabbit Hu E, R
0.1 mg / €390.00
  Abnova Taiwan Corp.

Endothelin-1 antibody

Endothelin-1 Mouse IgG2b 3B8C9 Ascites Hu E
0.1 ml / €400.00
  Novus Biologicals Inc.

Endothelin-1 antibody

Endothelin-1 Rat IgG2b 3G10 Ascites Hu C, P, R
0.1 mg / €290.00
  Novus Biologicals Inc.

Endothelin-1 antibody

Endothelin-1 Mouse IgG1 IC4 Hu ICC/IF, R
0.1 mg / €250.00
  Novus Biologicals Inc.

Endothelin-1 antibody

Figure 1 and Figure 2 show immunolocalization of ET-1 in human bowel using NB 300-526. Mouse IgG1 TR.ET.48.5 Ascites Hu, Rt, Sh C, ICC/IF, P, R, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Endothelin-1 antibody

Western  Blot:  Endothelin 1 Antibody [NBP1-33613] – Western blot analysis of Endothelin 1 on 293T (Lane A) and Hep G2 (Lane B) lysates using NBP1-33613 at a dilution of 1:1000. 30ug whole cell lysate loaded on 12% SDS PAGE gel. Rabbit IgG Hu ICC/IF, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Endothelin-1 antibody

Immunohistochemistry-Paraffin: Endothelin 1 Antibody [NBP1-84779] - Immunohistochemical staining of human smooth muscle shows distinct positivity in endothelial cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

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