Endothelin B receptor antibody

Principal name

Endothelin B receptor antibody

Alternative names for Endothelin B receptor antibody

ET-BR, ET-B, EDNRB, ETRB, ETB, ETBR, HSCR, WS4A, ABCDS, HSCR2, Endothelin receptor non-selective type, endothelin receptor type B

SwissProt ID

O62709 (Horse), P21451 (Rat), P24530 (Human), P28088 (Bovin), P35463 (Pig), P48302 (Mouse), P56497 (Canfa), Q8NHM8 (Human), Q9N0W7 (Rabit)

Gene ID

1910 (EDNRB), 50672 (Ednrb), 13618

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Mky (Monkey), Prim (Primate), Rt (Rat), Eq (Equine)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of Endothelin B receptor antibody

Endothelins (ET-1, 2, and 3) are considered to be very powerful vasoconstrictive substances. In humans, endothelins mediate their actions via two specific G-Protein coupled receptors, ETAR and ETBR. Both ETAR and ETBR are present in the heart and in human myocardium at similar levels. The endothelin receptors differ in their ligand specificity. While ETAR has varying affinities for the endothelin isoforms (ET-1 >ET-2>ET-3), ETBR shows no selective affinity. Subsequent studies have demonstrated the presence of endothelins in vascular as well as in non-vascular cells and tissues, having multiple biological activities. Currently there is increasing evidence that ET-1 may modulate mitogenesis, apoptosis, angiogenesis tumor invasion and the development of metastases. Until recently, it was thought that all cellular activities of the endothelins were mediated through their interactions with their cell surface receptors. However, a recent study demonstrated that cardiac nuclei also possess both ETAR and ETBR subtypes, which are functiol and coupled to sigling mechanisms within the nuclear membrane. Hypermethylation of the ETBR correlated with transcriptiol down-regulation and reduced expression of ETB receptor was observed in several prostate, bladder and colon cancer cell lines.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Endothelin B receptor (N-term, Extracel. Dom.) antibody

Figure 1. Immunohistochemical staining of Adrenal (Medulla) using anti-Endothelin B Receptor antibody SP4124P. Rabbit Aff - Purified Can, Hu, Mky, Prim ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Endothelin B receptor (N-term) antibody

  Rabbit Polyclonal Anti-EDNRB Antibody (N-Terminus)  
Anti-EDNRB / Endothelin B Receptor antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

Endothelin B receptor antibody

  Rabbit Polyclonal Endothelin B Receptor Antibody  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-EDNRB rabbit polyclonal antibody. (TA590006) Rabbit IgG Purified Hu E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Endothelin B receptor antibody

  Anti-EDNRB Rabbit Polyclonal Antibody  
Predicted band size: 50 kDa.Positive control: Hela cell, human lung, fetal intestine and fetal lung tissue lysate. Recommended dilution: 1/500-2000 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Endothelin B receptor antibody

  Rabbit anti-EDNRB Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using EDNRB antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Endothelin B receptor antibody

  Rabbit Polyclonal Anti-ET-B  
Western blot analysis of rat brain membranes: 1. Anti-Endothelin Receptor B antibody, (1:200). 2. Anti-Endothelin Receptor B antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Endothelin B receptor antibody

  Rabbit Polyclonal Anti-EDNRB Antibody (N-Terminus)  
Anti-EDNRB antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

Endothelin B receptor antibody

  Rabbit Polyclonal Anti-EDNRB Antibody (C-Terminus)  
Anti-EDNRB antibody IHC of human vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Eq, Hu
50 µg / €400.00
  OriGene Technologies, Inc.

Endothelin B receptor (C-term) antibody

Western blot analysis of EDNRB Antibody (C-term) (AP17303PU-N) in mouse cerebellum tissue lysates (35 µg/lane). EDNRB (arrow) was detected using the purified Pab. Rabbit Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Endothelin B receptor antibody

Endothelin B receptor Rabbit IgG Aff - Purified Hu WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

EDNRB - human gene knockout kit via CRISPR

EDNRB - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

EDNRB - human gene knockout kit via CRISPR

EDNRB - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

EDNRB - human gene knockout kit via CRISPR

EDNRB - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

EDNRB - human gene knockout kit via CRISPR

EDNRB - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ednrb - mouse gene knockout kit via CRISPR

Ednrb - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Ednrb - mouse gene knockout kit via CRISPR

Ednrb - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ednrb - mouse gene knockout kit via CRISPR

Ednrb - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ednrb - mouse gene knockout kit via CRISPR

Ednrb - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Endothelin B receptor (transcript variant 1)

  Recombinant protein of human endothelin receptor type B (EDNRB), transcript variant 1  
Endothelin B receptor Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

EDNRB overexpression lysate

EDNRB overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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