Eotaxin-2 / CCL24 antibody

Principal name

Eotaxin-2 / CCL24 antibody

Alternative names for Eotaxin-2 / CCL24 antibody

C-C motif chemokine 24, Small-inducible cytokine A24, MPIF2, MPIF-2, SCYA24, CK-beta-6, Myeloid progenitor inhibitory factor 2, Eosinophil chemotactic protein 2

SwissProt ID

O00175 (Human), Q68Y86 (Canfa), Q9JKC0 (Mouse)

Gene ID

6369 (CCL24), 56221 (Ccl24)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Goat, Rabbit, Rat

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Functional assay (FN), ELISA (detection) (E(detection)), Neutralisation (NEUT)

Background of Eotaxin-2 / CCL24 antibody

Eotaxin 2, also named MPIF2, Ckbeta6, and SCYA24, is a member of the CC chemokine family, based on the presence of the CC motif and homology with other known CC chemokines. Eotaxin 2 cDNA encodes a 119 amino acid residue precursor protein with a 26 amino acid residue signal peptide that is cleaved to generate a mature protein predicted to contain 93 amino acid residues with an N glycosylation site. Mature human eotaxin 2 has a predicted molecular mass of approximately 10.6 kDa. Compared to other CC chemokines, eotaxin 2 exhibits 40 %, 42 %, and 39 % amino acid identity to MCP3, MIP1 alpha, and eotaxin, respectively. Human CC chemokine eotaxin 2 maps to chromosome 7q11.23. Both eotaxin and eotaxin 2 activate and attract eosinophils and basophils. A receptor for human eotaxin has been identified and found to be the third numbered receptor in the C-C chemokine subfamily of receptors (CCR3. On eosinophils, the effects of eotaxin 2 is inhibited by an CCR3 antibody and cross-desensitized by eotaxin and MCP4, suggesting that all three CC chemokines act through CCR3. Eotaxin 2 mRNA is weakly expressed in activated monocytes and T lymphocytes. Recombinant eotaxin 2 induces chemotaxis of eosinophils, basophils, and resting T lymphocytes but not monocytes and activated T lymphocytes. Eotaxin 2 inhibits colony formation in myleloid progenitor cells.

General readings

General / background references:Nomiyama H et al. Assignment of the human CC chemokine MPIF-2/eotaxin-2 (SCYA24) to chromosome 7q11.23. Genomics 49:339-40 (1998). PubMed PMID: 9598329
Patel VP et al. Molecular and functional characterization of two novel human C-C chemokines as inhibitors of two distinct classes of myeloid progenitors. J Exp Med 185:1163-72 (1997). PubMed PMID: 9104803
Forssmann U et al. Eotaxin-2, a novel CC chemokine that is selective for the chemokine receptor CCR3, and acts like eotaxin on human eosinophil and basophil leukocytes. J Exp Med 185:2171-6 (1997). PubMed PMID: 9182688
White JR et al. Cloning and functional characterization of a novel human CC chemokine that binds to the CCR3 receptor and activates human eosinophils. J Leukoc Biol 62:667-75 (1997). PubMed PMID: 9365122
Kitaura M et al. Molecular cloning of human eotaxin, an eosinophil-selective CC chemokine, and identification of a specific eosinophil eotaxin receptor, CC chemokine receptor 3. J Biol Chem 271:7725-30 (1996). PubMed PMID: 8631813

Items 1 to 20 of 30 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Eotaxin-2 / CCL24 antibody

Predicted band size: 13 kDa . Positive control: Human lymphoma tissue lysate. Recommended dilution: 1/200-1000. (Gel: 12%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/400dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Eotaxin-2 / CCL24 antibody

Eotaxin-2 / CCL24 Goat Biotin Hu E, WB
50 µg / €340.00
  Acris Antibodies GmbH

Eotaxin-2 / CCL24 antibody

Eotaxin-2 / CCL24 Goat Biotin Hu E, WB
25 µg / €230.00
  Acris Antibodies GmbH

Eotaxin-2 / CCL24 antibody

Eotaxin-2 / CCL24 Goat Aff - Purified Hu E, FN, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Eotaxin-2 / CCL24 antibody

Eotaxin-2 / CCL24 Goat Aff - Purified Hu E, FN, WB
50 µg / €230.00
  Acris Antibodies GmbH

Eotaxin-2 / CCL24 antibody

Formalin-fixed, paraffin-embedded sections of human tonsil stained with Eotaxin-2 / CCL24 Antibody Cat.-No PM1323. Heat induced antigen retrieval with a pH 8.0 EDTA buffer is recommended. Mouse IgG1 Azide Free Hu E, P, WB
0.5 mg / €220.00
  Acris Antibodies GmbH

Eotaxin-2 / CCL24 antibody

Eotaxin-2 / CCL24 Goat IgG Biotin Ms E, WB
25 µg / €230.00
  Acris Antibodies GmbH

Eotaxin-2 / CCL24 antibody

Eotaxin-2 / CCL24 Goat Aff - Purified Ms E, FN, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Eotaxin-2 / CCL24 antibody

Eotaxin-2 / CCL24 Goat IgG Aff - Purified Ms E, FN, WB
50 µg / €230.00
  Acris Antibodies GmbH

Eotaxin-2 / CCL24 antibody

Western Blot analysis of CCL24 expression in transfected 293T cell line (H00006369-T01) by CCL24 MaxPab polyclonal antibody.

Lane 1: CCL24 transfected lysate(13.09 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Eotaxin-2 / CCL24 antibody

Western Blot analysis of CCL24 expression in transfected 293T cell line (H00006369-T01) by CCL24 MaxPab polyclonal antibody.

Lane 1: CCL24 transfected lysate(13.10 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Eotaxin-2 / CCL24 antibody

Eotaxin-2 / CCL24 Mouse IgG1 61016,11 Purified Hu E, WB
0.1 mg / €340.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Eotaxin-2 / CCL24

Eotaxin-2 / CCL24 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

Eotaxin-2 / CCL24

Eotaxin-2 / CCL24 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 20 µg / €199.00

Special Price: 20 µg / €139.00

  OriGene Technologies, Inc.

Eotaxin-2 / CCL24

Eotaxin-2 / CCL24 Mouse > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 20 µg / €199.00

Special Price: 20 µg / €139.00

  OriGene Technologies, Inc.

Eotaxin-2 / CCL24

Eotaxin-2 / CCL24 Human > 98 %
Preparation: .
Purity Detail: >98%, as determined by Coomassie stained SDS-PAGE.

Regular Price: 10 µg / €119.00

Special Price: 10 µg / €99.00

  OriGene Technologies, Inc.

Eotaxin-2 / CCL24

Eotaxin-2 / CCL24 Mouse > 98 %
Preparation: .
Purity Detail: >98%, as determined by Coomassie stained SDS-PAGE.

Regular Price: 10 µg / €119.00

Special Price: 10 µg / €99.00

  OriGene Technologies, Inc.

Eotaxin-2 / CCL24

Eotaxin-2 / CCL24 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Eotaxin-2 / CCL24

Eotaxin-2 / CCL24 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Eotaxin-2 / CCL24

Eotaxin-2 / CCL24 Human
20 µg / €290.00
  Abnova Taiwan Corp.

Items 1 to 20 of 30 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn