EP400 / P400 antibody

Principal name

EP400 / P400 antibody

Alternative names for EP400 / P400 antibody

Domino homolog, CAGH32, KIAA1498, KIAA1818, TNRC12, E1A-binding protein p400, CAG repeat protein 32, Trinucleotide repeat-containing gene 12 protein, p400 kDa SWI2/SNF2-related protein

SwissProt ID

Q8CHI8 (Mouse), Q8VDF4 (Mouse), Q96L91 (Human)

Gene ID

57634 (EP400)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Immunoprecipitation (IP), PLA/Proximity ligation assay (PLA), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of EP400 / P400 antibody

NuAR is a multi-protein histone acetyltransferase complex that functions to acetylate the nucleosomal Histones H4 and H2A, thereby activating transcription of select target genes. p400, also known as EP400 (E1A binding protein p400) or mDomino, localizes to the nucleus and is a component of the NuAR complex. Expressed in brain, liver, thymus, lung, spleen, colon and kidney, p400 regulates the transcriptional activity of proteins such as MZF-1 and contributes to the ATPase and helicase activities of NuA4. p400 is a SWI2/ SNF2-related protein that can interact with the adenovirus oncoprotein E1A, thus activating the proapoptotic activity of E1A. The ability of p400 to regulate transcriptional and apoptotic activity suggests that the NuAR complex may be a crucial component of cell proliferation, transformation and, possibly, carcinogenesis. Five isoforms of p400 exist due to alternative splicing events.

7 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EP400 / P400 antibody

Immunofluorescence of purified MaxPab antibody to EP400 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

EP400 / P400 antibody

Western Blot analysis of EP400 expression in transfected 293T cell line by EP400 monoclonal antibody (M01), clone 2A7.

Lane 1: EP400 transfected lysate(105.7 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 2A7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

EP400 / P400 antibody

Western Blot and IP: p400 Antibody [NB200-210] - Detection of Human p400 on HeLa whole cell lysate using NB200-210. Immunoprecipitation of  p400 was also accomplished, albeit less efficiently, using another rabbit  anti-p400 antibody. Rabbit Aff - Purified Hu IP, PLA, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

EP400 / P400 antibody

Immunohistochemistry-Paraffin: p400 Antibody [NBP1-88230] Immunohistochemical staining of human gall bladder shows strong nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

EP400 / P400

EP400 / P400 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

EP400 / P400

EP400 / P400 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

EP400 293T Cell Transient Overexpression Lysate(Denatured)

EP400 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

7 Item(s)

per page
  • LinkedIn