EPHA2 / ECK antibody

Principal name

EPHA2 / ECK antibody

Alternative names for EPHA2 / ECK antibody

Ephrin type-A receptor 2, Epithelial cell kinase, Eph receptor A2, Tyrosine-protein kinase receptor ECK

SwissProt ID

P29317 (Human), Q03145 (Mouse)

Gene ID

1969 (EPHA2), 13836 (Epha2)

Available reactivities

Hu (Human), Hst (Hamster), Ms (Mouse), Bov (Bovine), Can (Canine), Chimp (Chimpanzee), Eq (Equine), Mky (Monkey), Rt (Rat), Chk (Chicken)

Available hosts

Mouse, Rabbit, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), EPair for Elisa (EPair), Flow Cytometry (F), Frozen Sections (C), Immunoprecipitation (IP)

Background of EPHA2 / ECK antibody

Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration. During development, may function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. Involved for instance in angiogenesis, in early hindbrain development and epithelial proliferation and branching morphogenesis during mammary gland development. Engaged by the ligand ephrin-A5/EFNA5 may regulate lens fiber cells shape and interactions and be important for lens transparency development and maintenance. With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EPHA2 pTyr588/pTyr596 antibody

Western blot analysis of EPHA2 (pY588/596) expression in A431 (A); mouse brain (B) whole cell lysates. Rabbit Aff - Purified Chk, Hu, Mky, Ms, Rt ICC/IF, WB
30 µl / €210.00
  Cohesion Biosciences Ltd.

EPHA2 pTyr588/pTyr596 antibody

Western blot analysis of EPHA2 (pY588/596) expression in A431 (A); mouse brain (B) whole cell lysates. Rabbit Aff - Purified Chk, Hu, Mky, Ms, Rt ICC/IF, WB
0.1 ml / €330.00
  Cohesion Biosciences Ltd.

EPHA2 pTyr588/pTyr596 antibody

Western blot analysis of EPHA2 (pY588/596) expression in A431 (A); mouse brain (B) whole cell lysates. Rabbit Aff - Purified Chk, Hu, Mky, Ms, Rt ICC/IF, WB
0.2 ml / €530.00
  Cohesion Biosciences Ltd.

EPHA2 antibody

Western blot analysis of EPHA2 expression in HeLa (A); Jurkat (B); NIH3T3 (C) whole cell lysates. Rabbit Aff - Purified Chk, Hu, Mky, Ms, Rt ICC/IF, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

EPHA2 antibody

Western blot analysis of EPHA2 expression in HeLa (A); Jurkat (B); NIH3T3 (C) whole cell lysates. Rabbit Aff - Purified Chk, Hu, Mky, Ms, Rt ICC/IF, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

EPHA2 antibody

Western blot analysis of EPHA2 expression in HeLa (A); Jurkat (B); NIH3T3 (C) whole cell lysates. Rabbit Aff - Purified Chk, Hu, Mky, Ms, Rt ICC/IF, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

EPHA2/3/4 pTyr588/596 antibody

Western blot analysis of extracts from HepG2 cells using EPHA2/3/4 (Phospho-Tyr588/596) Antibody AP55721PU-N.The lane on the right is treated with the antigen-specific peptide. Rabbit Aff - Purified Hu, Ms ICC/IF, WB
0.1 ml / €340.00
  Acris Antibodies GmbH

EPHA2/3/4 pTyr588/596 antibody

Western blot analysis of extracts from HepG2 cells using EPHA2/3/4 (Phospho-Tyr588/596) Antibody AP55721PU-N.The lane on the right is treated with the antigen-specific peptide. Rabbit Aff - Purified Hu, Ms ICC/IF, WB
50 µl / €270.00
  Acris Antibodies GmbH

EPHA2 / ECK antibody

Immunohistochemistry: Formalin-Fixed, Paraffin-Embedded Human Thyroid stained with EPHA2 antibody at 5 µg/ml followed by biotinylated anti-mouse IgG secondary antibody  alkaline phosphatase-streptavidin and chromogen. Mouse IgG2b 3D7 Purified Hu, Ms E, P, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

EPHA2 / ECK antibody

Immunohistochemistry: Formalin-Fixed, Paraffin-Embedded Human Thyroid stained with EPHA2 antibody at 5 µg/ml followed by biotinylated anti-mouse IgG secondary antibody  alkaline phosphatase-streptavidin and chromogen. Mouse IgG2b 3D7 Purified Hu, Ms E, P, WB
50 µl / €230.00
  Acris Antibodies GmbH

EPHA2 / ECK antibody

Immunofluorescence of monoclonal antibody to EPHA2 on A-431 cell. [antibody concentration 10 ug/ml] Mouse IgG3 1E3 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

EPHA2 / ECK antibody

Human breast carcinoma stained with anti-EPHA2 / ECK Antibody Cat.-No AM32431PU (Clone SP169). Rabbit IgG SP169 Purified Hu F, P
0.5 ml / €520.00
  Acris Antibodies GmbH

EPHA2 / ECK antibody

Human breast carcinoma stained with anti-EPHA2 / ECK Antibody Cat.-No AM32431PU (Clone SP169). Rabbit IgG SP169 Purified Hu F, P
1 ml / €730.00
  Acris Antibodies GmbH

EPHA2 / ECK antibody

Human breast carcinoma stained with anti-EPHA2 / ECK Antibody Cat.-No AM32431PU (Clone SP169). Rabbit IgG SP169 Purified Hu F, P
0.1 ml / €360.00
  Acris Antibodies GmbH

EPHA2 / ECK antibody

Western blot analysis of extracts from NIH/3T3 cells, using EPHA2/3/4 (Ab-588/596) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

EPHA2 / ECK antibody

Western blot analysis of extracts from COLO205 and Jurkat cells, using EPHA2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

EPHA2 / ECK antibody

Western blot analysis of extracts from JK cells, using EPHA2/5 (Ab-594) Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

EPHA2 / ECK antibody

Western blot analysis on HepG2 cell lysate using EPHA2/3/4 Antibody Rabbit IgG Purified Hu, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EPHA2 / ECK antibody

Western blot analysis of EPHA2 expression in Jurkat cells Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EPHA2 / ECK antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY EPHA2 (RC205725, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-EPHA2. Rabbit IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

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