EphA6 antibody

Principal name

EphA6 antibody

Alternative names for EphA6 antibody

Ephrin type-A receptor 6, EPH homology kinase 2, Ehk-2, Ehk2, Tyrosine-protein kinase receptor EHK-2

SwissProt ID

P54758 (Rat), Q62413 (Mouse), Q9UF33 (Human)

Gene ID

285220 (EPHA6)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Rabbit, Rat

Available applications

Enzyme Immunoassay (E), Frozen Sections (C), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Flow Cytometry (F)

Background of EphA6 antibody

EphA6, also known as Ehk2 and Hek12, is a member of the Eph receptor family, which binds members of the Ephrin ligand family. Two classes of receptors exist, designated A and B, that have an extracellular domain made up of a globular domain, a cysteine-rich domain, and two fibronectin type III domains, followed by the transmembrane region and cytoplasmic region. The cytoplasmic region is a juxtamembrane region with two tyrosines, the major autophosphorylation sites, along with a kinase domain, and a conserved sterile alpha motif (SAM) in the C-terminus, the latter including one conserved tyrosine.The extracellular domains of mouse and rat EphA6 share approximately 99% amino acid identity. The calculated molecular mass of the reduced mouse EphA6/Fc monomer is approximately 86 kDa, but as a result of glycosylation, recombinant EphA6/Fc migrates as an approximately 100 kDa protein under reducing conditions in SDS-PAGE. Ligand recognition and binding leads to kinase activation of the intrinsic kinase activity. EphA6 binds to Ephrin A1, Ephrin A2, Ephrin A3, Ephrin A4 and Ephrin A5. Only membrane-bound or Fc-clustered ligands have been shown to activate the receptor in vitro. Soluble monomeric ligands bind the receptor, but do not induce receptor autophosphorylation and activation. The ephrin ligands and Eph receptors display reciprocal expression in vivo. Developing and adult neural tissue express nearly all of the Eph receptors and ephrin ligands. Ephs and ephrins play a significant role in angiogenesis.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EphA6 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using EPHA6 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

EphA6 antibody

WB Suggested Anti-EPHA6 Antibody; Titration: 1.0 ug/ml; Positive Control: 721_B Whole Cell Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

EphA6 antibody

Western blot analysis using EphA6 antibody Cat.-No AM06292SU-N against truncated MBP-EphA6 recombinant protein (Lane1) and truncated GST-EphA6(aa695-795) recombinant protein (Lane 2). Mouse IgG1 3D5B10 Ascites Hu WB
0.1 ml / €400.00
  Acris Antibodies GmbH

EphA6 (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu, Ms P
0.4 ml / €370.00
  Acris Antibodies GmbH

EphA6 antibody

Western blot analysis of EphA6 (arrow) using rabbit polyclonal EphA6 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the EPHA6 gene (Lane 2) Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

EphA6 (C-term) antibody

Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Hu, Ms, Rt E, ICC/IF, P
50 µg / €470.00
  Acris Antibodies GmbH

EphA6 antibody

EphA6 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

EphA6 antibody

EphA6 Mouse IgG1 2H2 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

EphA6 antibody

EphA6 Rabbit Hu, Ms C, E
0.4 ml / €390.00
  Abnova Taiwan Corp.

EphA6 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using EPHA6 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P
50 µg / €205.00
  Assay Biotech

EphA6 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using EPHA6 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P
0.1 mg / €310.00
  Assay Biotech

EphA6 antibody

Immunohistochemistry: Eph receptor A6 Antibody (9J12) [NB110-93605] - Paraffin pancreas and kidney sections from LPS treated mice were subjected to IHC using anti EphA6 antibody RM0054-9J12. Rat IgG1 9J12 Purified Ms WB
0.1 mg / €450.00
  Novus Biologicals Inc.

EphA6 antibody

Western Blot: Eph receptor A6 Antibody (3D5B10) [NBP1-51559] - Western blot analysis using EphA6 mouse mAb against truncated MBP-EphA6 recombinant protein (1) and truncated GST-EphA6(aa695-795) recombinant protein (2). Mouse IgG1 3D5B10 Purified Hu E, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

EphA6 antibody

EphA6 Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P
0.1 mg / €360.00
  Novus Biologicals Inc.

EphA6 antibody

EphA6 Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P
50 µg / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

EphA6

EphA6 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

EphA6

EphA6 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

EphA6

EphA6 Human
5 µg / €530.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

EPHA6 overexpression lysate

EPHA6 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

EPHA6 overexpression lysate

EPHA6 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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