EPHA7 antibody

Principal name

EPHA7 antibody

Alternative names for EPHA7 antibody

EHK3, HEK11, Ephrin type-A receptor 7, Tyrosine-protein kinase receptor EHK-3, EPH homology kinase 3, Receptor protein-tyrosine kinase HEK11

SwissProt ID

O42422 (Chick), P54759 (Rat), Q15375 (Human), Q61772 (Mouse)

Gene ID

2045 (EPHA7), 4204515 (accD)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Chk (Chicken), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Goat, Rabbit, Mouse, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Frozen Sections (C), Flow Cytometry (F)

Background of EPHA7 antibody

EphA7, also known as Mdk1, Hek11, Ehk3, Ebk, and Cek11, is a member of the Eph receptor family, which binds members of the ephrin ligand family. Two classes of receptors exist, designated A and B, that have an extracellular domain made up of a globular domain, a cysteine-rich domain, and two fibronectin type III domains, followed by the transmembrane region and cytoplasmic region. The cytoplasmic region is a juxtamembrane region with two tyrosines, the major autophosphorylation sites, along with a kinase domain, and a conserved sterile alpha motif (SAM) in the C-terminus, the latter including one conserved tyrosine. The extracellular domains of human and mouse EphA7 share 97% amino acid identity. The calculated molecular mass of the reduced mouse EphA7/Fc monomer is 85.7 kDa, but as a result of glycosylation, recombinant EphA7/Fc migrates as an approximately 110 kDa protein under reducing conditions in SDS-PAGE.Ligand recognition and binding leads to activation of the intrinsic kinase activity. EphA7 binds to ephrin A1, ephrin A2, ephrin A3, ephrin A4, and ephrin A5. Only membrane-bound or Fc-clustered ligands have been shown to activate the receptor in vitro. Soluble monomeric ligands can bind the receptor, but do not induce receptor autophosphorylation and activation. The ephrin ligands and eph receptors display reciprocal expression in vivo. Developing and adult neural tissue express nearly all of the Eph receptors and ephrin ligands. Ephs and ephrins play a significant role in angiogenesis.

General readings

General / background references:Flanagan JG & Vanderhaeghen P The ephrins and Eph receptors in neural development. Annu Rev Neurosci 21:309-45 (1998). PubMed PMID: 9530499
Pasquale EB The Eph family of receptors. Curr Opin Cell Biol 9:608-15 (1997). PubMed PMID: 9330863

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

EPHA7 antibody

Western blot analysis of extracts from JK cells, using EPHA7 (Ab-791)antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

EPHA7 antibody

Western blot analysis of extracts from Jurkat cells and COLO205 cells, using EPHA7 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

EPHA7 antibody

Host:Rabbit; Target Name:EPHA7; Sample Tissue:Human Fetal Liver; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

EPHA7 antibody

Western blot analysis on JK cell lysate using EPHA7 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

EPHA7 antibody

Immunohistochemical analysis of paraffin-embedded Human Breast tissues using EPHA7 antibody Cat.-No AM06281SU-N Mouse IgG2b 6C8G7 Ascites Hu P, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

EPHA7 antibody

Western blot (WB) analysis of EphA7 antibody (Cat.-No.: AP06735PU-N) in extracts from Jurkat cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

EPHA7 (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

EPHA7 antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with EphA7 antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

EPHA7 pTyr791 antibody

Western blot analysis of extracts from JK cells (Lane 2), using EPHA7 (Phospho-Tyr791) Antibody AP55849PU-N. The lane on the left is treated with antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €340.00
  Acris Antibodies GmbH

EPHA7 pTyr791 antibody

Western blot analysis of extracts from JK cells (Lane 2), using EPHA7 (Phospho-Tyr791) Antibody AP55849PU-N. The lane on the left is treated with antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µl / €270.00
  Acris Antibodies GmbH

EPHA7 antibody

Western Blot analysis of EPHA7 expression in transfected 293T cell line (H00002045-T01) by EPHA7 MaxPab polyclonal antibody.

Lane 1: EPHA7 transfected lysate(30.69 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

EPHA7 antibody

Immunoprecipitation of EPHA7 transfected lysate using anti-EPHA7 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with EPHA7 MaxPab mouse polyclonal antibody (B01) (H00002045-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

EPHA7 antibody

EPHA7 Mouse IgM 1G11 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

EPHA7 antibody

EPHA7 Mouse IgM 3D11 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

EPHA7 antibody

EPHA7 Mouse IgM 3C3 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

EPHA7 antibody

Western blot analysis of extracts from Jurkat cells/COLO205 cells, using EPHA7 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

EPHA7 antibody

Western blot analysis of extracts from Jurkat cells/COLO205 cells, using EPHA7 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

EPHA7 antibody

Western blot analysis of EPHA7 expression in HEK293T (A); Jurkat (B) whole cell lysates. Rabbit Aff - Purified Chk, Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

EPHA7 antibody

Western blot analysis of EPHA7 expression in HEK293T (A); Jurkat (B) whole cell lysates. Rabbit Aff - Purified Chk, Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

EPHA7 antibody

Western blot analysis of EPHA7 expression in HEK293T (A); Jurkat (B) whole cell lysates. Rabbit Aff - Purified Chk, Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

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