Ephrin-B2 antibody

Principal name

Ephrin-B2 antibody

Alternative names for Ephrin-B2 antibody

EFNB2, EPLG5, HTKL, LERK5, HTK-L, LERK-5, HTK ligand, EPH-related receptor tyrosine kinase ligand 5

SwissProt ID

O73874 (Danre), P52799 (Human), P52800 (Mouse)

Gene ID

13642 (Efnb2), 1948 (EFNB2)

Available reactivities

Ms (Mouse), Rt (Rat), Hu (Human), Bov (Bovine), Can (Canine), Por (Porcine)

Available hosts

Goat, Mouse, Rabbit

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of Ephrin-B2 antibody

The membrane bound Ephrins are ligands for Ephrin receptor tyrosine kinases that regulate several physiological functions including long-term potentiation, cell positioning, CNS development and axonal path finding and mitogenesis etc. Ephrins molecules exhibit the ability to send bidirectional signals following ligand-receptor interactions resulting from cell-cell contacts. Activation of Eph receptors are also shown to regulate transduction pathways important in cell cycle control as well as cell death. There are at least 4 different kinds of Ephrin B receptors are cloned (Ephrin B1R-Ephrin B4R). EphB receptor tyrosine kinases and ephrin-B ligands also regulate several types of cell-cell interactions during brain development, generally by modulating the cytoskeleton. EphB/ephrinB genes are expressed in the developing neural tube of early mouse embryos with distinct overlapping expression in the ventral midbrain. The positioning of cells within the stem cell niche in the intestinal epithelium is controlled by B subclass ephrins through their interaction with EphB receptors. Ephrin 3 ligands are also known as guidance molecule as they are mainly responsible for positioning and directing the cell migration along the villus-crypt axis in intestine. Ephrin 3 by interacting with ephrin B3 receptors in conjunction with Wnt proteins signals and promotes cell cycle re-entry of proginator cells and accounts for 50% of the mitogenic activity. The Ephrin B receptors are the key coordinators of the intestinal stem cell niche (1).
Ephrin B3 ligands are highly expressed in the mossy fibers axons and terminals and the Ephrins B3 receptors are expressed on post-synaptic neurons. Ephrin-B3 promotes adhesion of hippocampal neurons to the ligand-expressing substrates in vitro, and the loss of the receptor or EphB2 abrogates the effects of ephrin-B3 (2). The function of Ephrins in the immune system has not been well studied, although some Ephrins and Ephrin receptors are expressed at high levels on certain leukocytes. EFNB3 and its cognate receptors are expressed in peripheral T cells and monocytes/macrophages. The role of EphR2 and EphR4 in angiogenesis and formation of arteries and veins come form findings that EphR2 marks arteries but not veins and conversely, the EphR4 labels exclusively the veins (3).

General readings

Zhang, R., et al. Psychiatry Res 180(1):5-9(2010)
Bochenek, M.L., et al. J. Cell. Sci. 123 (PT 8), 1235-1246 (2010)
Nakada, M., et al. Int. J. Cancer 126(5):1155-1165(2010)
Qin, H., et al. J. Biol. Chem. 285(1):644-654(2010)
Kwan Tat, S., et al. Arthritis Res. Ther. 11 (4), R119 (2009).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Ephrin-B2 antibody

Western blot analysis of extracts from HUVEC cells untreated or treated with insulin or EGF, using Ephrin-B2 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Ephrin-B2 antibody

(0.1ug/ml) staining of Rat Lung lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Ephrin-B2 antibody

Predicted cell location: Cytoplasm. Positive control: Human esophagus and colon cancer tissue. Recommended dilution: 1/100-300  The image on the left is immunohistochemistry of paraffin-embedded Human esophagus and colon cancer tissue using EFNB2 antibody at dilution 1/80, on the right is treated with the fusion protein. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Ephrin-B2 (Center) antibody

EFNB2 Antibody (Center) (Cat. #TA324420) western blot analysis in Hela,293 cell line lysates (35ug/lane).This demonstrates the EFNB2 antibody detected the EFNB2 protein (arrow). Rabbit Ig Aff - Purified Hu ICC/IF, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Ephrin-B2 antibody

Western blot analysis of extracts of various cell lines, using EFNB2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Ephrin-B2 antibody

Figure 1. Western blot analysis of extract from HUVEC cells, untreated or treated with Insulin or EGF, using Ephrin-B2 antibody AP02707PU. Rabbit Aff - Purified Hu, Ms WB
0.1 ml / €270.00
  Acris Antibodies GmbH

Ephrin-B2 antibody

Figure 1. Western blot analysis of extract from HUVEC cells, untreated or treated with Insulin or EGF, using Ephrin-B2 antibody AP02707PU. Rabbit Aff - Purified Hu, Ms WB
50 µl / €230.00
  Acris Antibodies GmbH

Ephrin-B2 antibody

Immunofluorescence staining of methanol-fixed HeLa cells using Ephrin-B2 antibody AP02708PU (Red) Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 ml / €270.00
  Acris Antibodies GmbH

Ephrin-B2 antibody

Immunofluorescence staining of methanol-fixed HeLa cells using Ephrin-B2 antibody AP02708PU (Red) Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
50 µl / €230.00
  Acris Antibodies GmbH

Ephrin-B2 Control Peptide

Ephrin-B2
0.25 mg / €250.00
  Acris Antibodies GmbH

Ephrin-B2 (204-225) antibody

Ephrin-B2 Rabbit Aff - Purified Hu E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Ephrin-B2 pTyr316 antibody

Western blot analysis of extracts from HT29 cells, untreated or treated with UV using Ephrin-B2 (Phospho-Tyr316) Antibody AP26036PU-N. Rabbit Aff - Purified Hu, Ms WB
0.1 ml / €320.00
  Acris Antibodies GmbH

Ephrin-B2 pTyr316 antibody

Western blot analysis of extracts from HT29 cells, untreated or treated with UV using Ephrin-B2 (Phospho-Tyr316) Antibody AP26036PU-N. Rabbit Aff - Purified Hu, Ms WB
50 µl / €240.00
  Acris Antibodies GmbH

Ephrin-B2 pTyr330 antibody

Western blot analysis of extracts from HT29 cells, untreated or treated with UV using Ephrin-B2 (Phospho-Tyr330) Antibody AP26037PU-N. Rabbit Aff - Purified Hu, Ms WB
0.1 ml / €320.00
  Acris Antibodies GmbH

Ephrin-B2 pTyr330 antibody

Western blot analysis of extracts from HT29 cells, untreated or treated with UV using Ephrin-B2 (Phospho-Tyr330) Antibody AP26037PU-N. Rabbit Aff - Purified Hu, Ms WB
50 µl / €240.00
  Acris Antibodies GmbH

Ephrin-B2 antibody

EFNB2 polyclonal antibody (A01), Lot # 050912JC01 Western Blot analysis of EFNB2 expression in 293 ( Cat # L026V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Ephrin-B2 antibody

Western blot analysis of extract from HUVEC cells , untreated or treated with Insulin or EGF , using EFNB2 polyclonal antibody ( Cat # PAB5347 ) . Rabbit Hu, Ms, Rt WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Ephrin-B2 pTyr330 antibody

Western blot analysis of extracts from 293 cells treated with TNF-a 20ng/ml 30', using EFNB1/2 (Phospho-Tyr330) Antibody. The lane on the left is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

Ephrin-B2 pTyr330 antibody

Western blot analysis of extracts from 293 cells treated with TNF-a 20ng/ml 30', using EFNB1/2 (Phospho-Tyr330) Antibody. The lane on the left is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

Ephrin-B2 antibody

Ephrin-B2 Goat Aff - Purified Ms, Rt C, E, WB
0.1 mg / €450.00
  Neuromics Antibodies

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