Epsin-2 antibody

Principal name

Epsin-2 antibody

Alternative names for Epsin-2 antibody

EPN2, KIAA1065, EPS-15-interacting protein 2

SwissProt ID

O95208 (Human), Q8CHU3 (Mouse), Q9Z1Z3 (Rat)

Gene ID

22905 (EPN2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken), African clawed frog, Mky (Monkey), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of Epsin-2 antibody

Elucidation of the mechanism by which receptor tyrosine kinases (RTKs) modulate cellular physiology in response to stimuli is critical to the understanding of growth regulation. Miscues in RTK signaling pathways can result in cellular transformation and ultimately in cancer. Two novel EGF receptor substrates have been described, designated EGF-receptor pathway substrates 8 and 15, or Eps8 and Eps15. Epsin is a binding partner to Eps15. Both epsin and Eps15 have an ubiquitous tissue distribution but are concentrated in presynaptic nerve terminals specialized for the Clathrin-mediated endocytosis of synaptic vesicles. Disruption of epsin function blocks Clathrin-mediated endocytosis. Epsin, along with its binding partner Eps15, is proposed to be involved in the assistance of Clathrin coat rearrangement during Clathrin coated pit invagination. Epsin 2a, and 2b are splicing variants of epsin 2, which is associated with Clathrin-mediated endocytosis and are enriched in the brain in the peri-Golgi region.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Epsin-2 antibody

Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-EPN2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504295) Mouse IgG1 OTI1H3 Purified Hu, Mky ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Epsin-2 antibody

Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-EPN2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504296) Mouse IgG1 OTI1G3 Purified Hu, Mky F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Epsin-2 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-EPN2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504297) Mouse IgG1 OTI1C2 Purified Hu, Mky, Rt F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Epsin-2 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-EPN2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504298) Mouse IgG1 OTI1F1 Purified Hu, Mky ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Epsin-2 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-EPN2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504299) Mouse IgG1 OTI1B4 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Epsin-2 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-EPN2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504300) Mouse IgG1 OTI1C5 Purified Hu, Mky ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Epsin-2 antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-EPN2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504301) Mouse IgG1 OTI1F5 Purified Hu, Mky P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Epsin-2 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-EPN2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504302) Mouse IgG1 OTI1E4 Purified Hu, Mky P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Epsin-2 antibody

Western blot analysis of extracts from HepG2 cells and HUVEC cells, using EPN2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Epsin-2 antibody

WB Suggested Anti-EPN2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: 293T cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Epsin-2 antibody

WB Suggested Anti-EPN2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human Fetal brain Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Epsin-2 antibody

Western blot analysis on HepG2 cell lysate using EPN2 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Epsin-2 antibody

Western blot (WB) analysis of Epsin 2 antibody (Cat.-No.: AP01400PU-N) in extracts from HepG2 cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Epsin-2 (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Epsin-2 antibody

Epsin-2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Epsin-2 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with EPN2 polyclonal antibody ( Cat # PAB1710 ) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu, Ms E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

Epsin-2 antibody

Western blot analysis of extracts from HepG2/HuvEc cells, using EPN2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

Epsin-2 antibody

Western blot analysis of extracts from HepG2/HuvEc cells, using EPN2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

Epsin-2 antibody

Human 293T; WB Suggested Anti-EPN2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: 293T cell lysate. EPN2 is supported by BioGPS gene expression data to be expressed in HEK293T.; EPN2 antibody - middle region (ARP55479_P050) in Human 293T cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Epsin-2 antibody

Human Brain; WB Suggested Anti-EPN2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human brain; EPN2 antibody - middle region (ARP55480_P050) in Human Brain cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

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