ERAP1 / ARTS1 antibody

Principal name

ERAP1 / ARTS1 antibody

Alternative names for ERAP1 / ARTS1 antibody

APPILS, KIAA0525, Aminopeptidase PILS, ARTS-1, Endoplasmic reticulum aminopeptidase 1, Adipocyte-derived leucine aminopeptidase, Puromycin-insensitive leucyl-specific aminopeptidase, Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator

SwissProt ID

Q9EQH2 (Mouse), Q9JJ22 (Rat), Q9NZ08 (Human)

Gene ID

51752 (ERAP1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bt (Bat), Can (Canine), Mky (Monkey), Por (Porcine), Rb (Rabbit), Bov (Bovine), Eq (Equine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP)

Background of ERAP1 / ARTS1 antibody

The endoplasmic reticulum (ER) aminopeptidase 1 (ERAP1) is a 120 kDa protein localized to the lumen of the ER, which removes NH2-terminal residues from many antigenic precursors for MHC class I peptide presentation. Peptides that are presented by MHC class I on the surface of a cell must be 8-11 residues long, and ERAP1 specifically trims peptides of 9 amino acids or more. ERAP1 is also induced by interferon-gamma. The gene encoding human ERAP1 maps to chromosome 5q15. ERAP1 has previously been characterized as adipocyte-derived leucine aminopeptidase (A-LAP), puromycin-insensitive leucine-specific aminopeptidase (PILS-AP) and aminopeptidase regulator of TNFR1 shedding (ARTS-1). A-LAP is thought to inactivate several bioactive peptides, including angiotensin II and, subsequently, may be involved in the regulation of blood pressure. PILS-AP is described as playing a role in angiogenesis by regulating the proliferation and migration of endothelial cells, and ARTS-1 is characterized as a TNFR1 binding protein that promotes TNFR1 shedding. Further research will be necessary to fully elucidate the functions of this protein.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ERAP1 / ARTS1 antibody

Western blot analysis of extracts from HepG2 cells, Jurkat cells and HUVEC cells, using ARTS-1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ERAP1 / ARTS1 antibody

Western blot analysis of ERAP1 in SK-N-SH cell lysate with ERAP1 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Purified Hu, Ms ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ERAP1 / ARTS1 antibody

Anti-ERAP1 / ARTS1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu
50 µg / €379.00
  OriGene Technologies, Inc.

ERAP1 / ARTS1 antibody

Anti-ERAP1 / ARTS1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Bt, Can, Hu, Mky, Por, Rb
50 µg / €379.00
  OriGene Technologies, Inc.

ERAP1 / ARTS1 antibody

Anti-ERAP1 / ARTS1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Aff - Purified Hu P
50 µg / €379.00
  OriGene Technologies, Inc.

ERAP1 / ARTS1 antibody

Anti-ERAP1 / ARTS1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu P
50 µg / €379.00
  OriGene Technologies, Inc.

ERAP1 / ARTS1 antibody

Immunohistochemistry (IHC) analysis of ERAP1 antibody (Cat.-No.: AP06756PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

ERAP1 / ARTS1 antibody

Western blot analysis of anti-ARTS1 Antibody (Center) in Ramos cell line lysates (35ug/lane). ARTS1 (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ERAP1 / ARTS1 antibody

ARTS-1 monoclonal antibody (M01), clone 4H8 Western Blot analysis of ARTS-1 expression in A-431 ( Cat # L015V1 ). Mouse IgG1 4H8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ERAP1 / ARTS1 antibody

Western blot analysis of extracts from HepG2/Jurkat/HuvEc cells, using ARTS-1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

ERAP1 / ARTS1 antibody

Western blot analysis of extracts from HepG2/Jurkat/HuvEc cells, using ARTS-1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

ERAP1 / ARTS1 antibody

Immunohistochemical analysis of ERAP1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, IP, P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

ERAP1 / ARTS1 antibody

Immunohistochemical analysis of ERAP1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, IP, P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

ERAP1 / ARTS1 antibody

Immunohistochemical analysis of ERAP1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, IP, P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

ERAP1 / ARTS1 antibody

ERAP1 / ARTS1 Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

ERAP1 / ARTS1 antibody

ERAP1 / ARTS1 Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

ERAP1 / ARTS1 antibody

ERAP1 / ARTS1 Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
50 µg / €290.00
  Novus Biologicals Inc.

ERAP1 / ARTS1 antibody

Immunohistochemistry-Paraffin: ARTS1 Antibody (EPR6069) [NBP1-95861] human uterus tissue using anti-ERAP1. Rabbit EPR6069 Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ERAP1 / ARTS1 (transcript variant 2)

ERAP1 / ARTS1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

ERAP1 / ARTS1 (transcript variant 1)

ERAP1 / ARTS1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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