ERAP2 / LRAP antibody

Principal name

ERAP2 / LRAP antibody

Alternative names for ERAP2 / LRAP antibody

L-RAP, Endoplasmic reticulum aminopeptidase 2, Leukocyte-derived arginine aminopeptidase

SwissProt ID

A6QPT7 (Bovin), Q6P179 (Human)

Gene ID

64167 (ERAP2)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of ERAP2 / LRAP antibody

The endoplasmic reticulum (ER) aminopeptidase 2 (ERAP2), a member of the peptidase M1 family, like the related protein ERAP1, plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides (1,2). Like ERAP1, ERAP2 is localized to the lumen of the ER and is thought to associate with ERAP1 as a heterodimer (1). Both ERAP1 and ERAP2 have been linked to several human diseases ranging from infections to autoimmunity and cancer, and may play a role in the inte immune response (reviewed in 3).

General readings

Saveanu L, Carroll O, Lindo V, Del Val M, Lopez D, Lepelletier Y, Greer F, Schomburg L, Fruci D, Niedermann G, van Endert PM.
Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.
Nat Immunol. 2005 Jul;6(7):689-97
PMID: 15908954

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ERAP2 / LRAP antibody

TA305860 (0.5ug/ml) staining of Spleen lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ERAP2 / LRAP antibody

Western blot analysis of ERAP2 in rat small intestine tissue lysate with ERAP2 antibody at 1 ug/ml. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ERAP2 / LRAP antibody

LRAP MaxPab polyclonal antibody. Western Blot analysis of LRAP expression in human kidney. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

ERAP2 / LRAP antibody

ERAP2 polyclonal antibody ( Cat # PAB11523 ) ( 0.5 µg/ml ) staining of human spleen lysate ( 35 µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

ERAP2 / LRAP antibody

Western Blot: ERAP2 Antibody  [NBP1-20913]-(0.5ug/ml) staining of Spleen lysate (35ug protein in RIPA buffer) Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ERAP2 / LRAP

ERAP2 / LRAP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

ERAP2 / LRAP

ERAP2 / LRAP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

LRAP 293T Cell Transient Overexpression Lysate(Denatured)

LRAP 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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