ERCC3 antibody

Principal name

ERCC3 antibody

Alternative names for ERCC3 antibody

ERCC-3, XPB, XPBC, BTF2-p89, TFIIH basal transcription factor complex helicase XPB subunit, Basic transcription factor 2 89 kDa subunit, TFIIH 89 kDa subunit, DNA repair protein complementing XP-B cells, Xeroderma pigmentosum group B-complementing protein, DNA excision repair protein ERCC-3

SwissProt ID

P19447 (Human), P49135 (Mouse), Q1RMT1 (Bovin), Q4G005 (Rat), Q5ZKK7 (Chick)

Gene ID

2071 (ERCC3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Bov (Bovine), Can (Canine), Por (Porcine), Rb (Rabbit), Ye (Yeast), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of ERCC3 antibody

XPB and XPD are ATPase/helicase subunits of the TFIIH complex that are involved in nucleotide excision repair (NER) to remove lesions and photoproducts generated by UV light . XPB and XPD are 3’-5’ and 5’-3’ D helicases, respectively, that play a role in opening of the D damage site to facilitate repair . XPB and XPD both play an important role in maintaining genomic stability, and researchers have linked mutations of these proteins to Xeroderma Pigmentosum (XP) and Trichothiodystrophy (TTD). XP patients have abnormalities in skin pigmentation and are highly susceptible to skin cancers, while TTD patients exhibit symptoms such as brittle hair, neurological abnormalities, and mild photosensitivity . In addition to their role in NER, XPB and XPD are involved in transcription initiation as part of the TFIIH core complex . The helicase activity of XPB unwinds D around the transcription start site to facilitate R polymerase II promoter clearance and initiation of transcription . XPD plays a structural role linking core TFIIH components with the cdk-activating kise (CAK) complex that phosphorylates the C-terminus of the largest subunit of R polymerase II, leading to transcription initiation .

15 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ERCC3 antibody

Sample (30 ug of whole cell lysate). A: 293T. B: A431 . C: H1299. 7.5% SDS PAGE. TA308754 diluted at 1:1000. Rabbit IgG Aff - Purified Hu, Ms ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ERCC3 (242-261) antibody

Anti-ERCC3 / XPB antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. Mouse IgG2b 3G4 Purified Hu E, IP, P, WB
50 µg / €345.00
  OriGene Technologies, Inc.

ERCC3 antibody

Predicted band size: 89 kDa . Positive control: COLO320 cell lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ERCC3 antibody

Western blot analysis of extracts of various cell lines, using ERCC3 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ERCC3 antibody

WB Suggested Anti-ERCC3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: HCT15 cell lysateERCC3 is supported by BioGPS gene expression data to be expressed in HCT15 Rabbit IgG Purified Bov, Can, Hu, Por, Rb, Ye, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

ERCC3 antibody

ERCC3 polyclonal antibody (A01), Lot # 050722JC01 Western Blot analysis of ERCC3 expression in HL-60 ( Cat # L014V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

ERCC3 antibody

ERCC3 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

ERCC3 antibody

Immunohistochemistry-Paraffin: XPB Antibody [NB100-61059] - FFPE section of human prostate carcinoma.  Affinity purified rabbit anti-ERCC3 used at a dilution of 1:500. Detection: DAB staining using Immunohistochemistry Accessory Kit Rabbit IgG Aff - Purified Hu IP, P
0.1 mg / €440.00
  Novus Biologicals Inc.

ERCC3 antibody

Western Blot and Immunoprecipitation: ERCC3 Antibody [NB100-61060] - Detection of Human and Mouse ERCC3 on HeLa whole cell lysate using NB100-61060. ERCC3 was also immunoprecipitated by rabbit anti-ERCC3 antibody NB100-61059. Rabbit IgG Aff - Purified Hu, Ms IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

ERCC3 antibody

Immunofluorescence: XPB Antibody [NBP1-31389] - Immunofluorescence analysis of HeLa, using NBP1-31389 at 1:200 dilution. Rabbit IgG Hu ICC/IF, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ERCC3

ERCC3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

ERCC3

ERCC3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

ERCC3

ERCC3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

ERCC3

ERCC3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ERCC3 overexpression lysate

ERCC3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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