ERCC3 antibody

Principal name

ERCC3 antibody

Alternative names for ERCC3 antibody

ERCC-3, XPB, XPBC, BTF2-p89, TFIIH basal transcription factor complex helicase XPB subunit, Basic transcription factor 2 89 kDa subunit, TFIIH 89 kDa subunit, DNA repair protein complementing XP-B cells, Xeroderma pigmentosum group B-complementing protein, DNA excision repair protein ERCC-3

SwissProt ID

P19447 (Human), P49135 (Mouse), Q1RMT1 (Bovin), Q4G005 (Rat), Q5ZKK7 (Chick)

Gene ID

2071 (ERCC3), 13872 (Ercc3), 291703

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine), Rb (Rabbit), Ye (Yeast), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P)

Background of ERCC3 antibody

XPB and XPD are ATPase/helicase subunits of the TFIIH complex that are involved in nucleotide excision repair (NER) to remove lesions and photoproducts generated by UV light . XPB and XPD are 3’-5’ and 5’-3’ D helicases, respectively, that play a role in opening of the D damage site to facilitate repair . XPB and XPD both play an important role in maintaining genomic stability, and researchers have linked mutations of these proteins to Xeroderma Pigmentosum (XP) and Trichothiodystrophy (TTD). XP patients have abnormalities in skin pigmentation and are highly susceptible to skin cancers, while TTD patients exhibit symptoms such as brittle hair, neurological abnormalities, and mild photosensitivity . In addition to their role in NER, XPB and XPD are involved in transcription initiation as part of the TFIIH core complex . The helicase activity of XPB unwinds D around the transcription start site to facilitate R polymerase II promoter clearance and initiation of transcription . XPD plays a structural role linking core TFIIH components with the cdk-activating kise (CAK) complex that phosphorylates the C-terminus of the largest subunit of R polymerase II, leading to transcription initiation .

16 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ERCC3 antibody

  Rabbit polyclonal antibody to XPB (excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing))  
Sample (30 ug of whole cell lysate). A: 293T. B: A431 . C: H1299. 7.5% SDS PAGE. TA308754 diluted at 1:1000. Rabbit IgG Aff - Purified Hu, Ms ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ERCC3 (242-261) antibody

  ERCC3 / XPB Mouse Monoclonal (aa242-261) (3G4) Antibody  
Anti-ERCC3 / XPB antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. Mouse IgG2b 3G4 Purified Hu E, IP, P, WB
50 µg / €400.00
  OriGene Technologies, Inc.

ERCC3 antibody

  Anti-ERCC3 Rabbit Polyclonal Antibody  
Predicted band size: 89 kDa . Positive control: COLO320 cell lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ERCC3 antibody

  ERCC3 Rabbit Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using ERCC3 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ERCC3 antibody

  Rabbit Polyclonal Anti-ERCC3 Antibody  
WB Suggested Anti-ERCC3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: HCT15 cell lysateERCC3 is supported by BioGPS gene expression data to be expressed in HCT15 Rabbit IgG Purified Bov, Can, Hu, Por, Rb, Ye, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

ERCC3 - human gene knockout kit via CRISPR

ERCC3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ERCC3 - human gene knockout kit via CRISPR

ERCC3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ERCC3 - human gene knockout kit via CRISPR

ERCC3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ERCC3 - human gene knockout kit via CRISPR

ERCC3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

ERCC3 overexpression lysate

ERCC3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ERCC3 (mGFP-tagged) - Human excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) (ERCC3), 200 uL, >10^7 TU/mL

Lenti ORF particles, ERCC3 (mGFP-tagged) - Human excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) (ERCC3), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, ERCC3 (Myc-DDK tagged) - Human excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) (ERCC3) , 200 uL, >10^7 TU/mL

Lenti ORF particles, ERCC3 (Myc-DDK tagged) - Human excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) (ERCC3) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ercc3 (GFP-tagged) - Mouse excision repair cross-complementing rodent repair deficiency, complementation group 3 (Ercc3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ercc3 (GFP-tagged) - Mouse excision repair cross-complementing rodent repair deficiency, complementation group 3 (Ercc3), 200 uL, >10^7 TU/mL  
200 µl / €1,490.00
  OriGene Technologies, Inc.

Lenti ORF particles, Ercc3 (Myc-DDK-tagged) - Mouse excision repair cross-complementing rodent repair deficiency, complementation group 3 (Ercc3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ercc3 (Myc-DDK-tagged) - Mouse excision repair cross-complementing rodent repair deficiency, complementation group 3 (Ercc3), 200 uL, >10^7 TU/mL  
200 µl / €1,340.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ercc3 (GFP-tagged ORF) - Rat excision repair cross-complementing rodent repair deficiency, complementation group 3 (Ercc3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ercc3 (GFP-tagged ORF) - Rat excision repair cross-complementing rodent repair deficiency, complementation group 3 (Ercc3), 200 uL, >10^7 TU/mL  
200 µl / €1,490.00
  OriGene Technologies, Inc.

Lenti ORF particles, Ercc3 (Myc-DDK-tagged ORF) - Rat excision repair cross-complementing rodent repair deficiency, complementation group 3 (Ercc3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ercc3 (Myc-DDK-tagged ORF) - Rat excision repair cross-complementing rodent repair deficiency, complementation group 3 (Ercc3), 200 uL, >10^7 TU/mL  
200 µl / €1,340.00
  OriGene Technologies, Inc.

16 Item(s)

per page
  • LinkedIn